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Journal Articles

Triple Degradation of BTK, IKZF1 and IKZF3 in B-Cell Malignancies

Sara Morrow, BA, Dennis Dobrovolsky, PhD, Eric Wang, PhD, Radosław P. Nowak, PhD, Katherine Donovan, PhD, Tyler Faust, PhD, Guang Yang, PhD, Zhengnian Li, PhD, Eric Fischer, Steven P Treon, MD PhD FRCP, David M Weinstock, MD, Nathanael S. Gray, PhD

Blood (2018) 132 (Supplement 1): 263.

https://doi.org/10.1182/blood-2018-99-116895

Published: 2018

Journal Articles

Spatial Structure of Plasma Coagulation Factor XIII and Changes with Activation

Anna D. Protopopova, PhD, Andrea Ramirez, Rustem I. Litvinov, John W. Weisel, PhD

Blood (2018) 132 (Supplement 1): 19.

https://doi.org/10.1182/blood-2018-99-112806

Published: 2018

Journal Articles

Quantitative Structural Characterization of Fibrinogen's αC Regions in Fibrin Monomers and Oligomers

Anna D. Protopopova, PhD, Rustem I. Litvinov, MD PhD, Dmitry V. Klinov, PhD, Dennis K. Galanakis, MD, John W. Weisel, PhD

Blood (2017) 130 (Supplement 1): 1056.

https://doi.org/10.1182/blood.V130.Suppl_1.1056.1056

Published: 2017

Journal Articles

Phenotype Does Not Always Equal Function: HDAC Inhibitors and UM171, but Not SR1, Lead to Rapid Upregulation of CD90 on Non-Engrafting CD34+CD90-Negative Human Cells

Kevin A. Goncalves, PhD, Megan D. Hoban, Jennifer L. Proctor, BS, Hillary L. Adams, MS, Sharon L. Hyzy, MS, Anthony E. Boitano, PhD, Michael P. Cooke, PhD

Blood (2017) 130 (Supplement 1): 659.

https://doi.org/10.1182/blood.V130.Suppl_1.659.659

Published: 2017

Journal Articles

A Novel Megakaryocyte-Based Screening System Identifies Compounds That Promote Megakaryocyte Maturation and Platelet Production in Vitro

Si Jing Chen, PhD, Hideya Seo, Akitsu Hotta, Yohei Nishi, Akira Ohta, Koji Eto

Blood (2017) 130 (Supplement 1): 2329.

https://doi.org/10.1182/blood.V130.Suppl_1.2329.2329

Published: 2017

Journal Articles

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Melanie Gentil, MD, Patricia Hugues, Gladys Telliam, Ivan Sloma, PharmD,PhD, Seda Baykal, Jerome Artus, PhD, Agnes Guerci, MD, Hyacinthe Johnson Ansa, Adlen Foudi, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2015) 126 (23): 4013.

https://doi.org/10.1182/blood.V126.23.4013.4013

Published: 2015

Journal Articles

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

Christopher N Lewis, AB, Raghavan Chinnadurai, PhD, Jacques Galipeau, MD

Blood (2014) 124 (21): 1593.

https://doi.org/10.1182/blood.V124.21.1593.1593

Published: 2014

Journal Articles

Profiling Of Polycyclic Aromatic Hydrocarbons-Induced Genotoxicity In Peripheral Blood Stem Cells and Bone Marrow Mesenchymal Stem Cells

Hwan-Young Kim, Hye-Ran Kim, PhD, Trang Nguyen Thi Dai, Hee-Jo Baek, MD, PhD, Jae-Dong Moon, MD, PhD, Jong-Hee Shin, MD, PhD, Soon-Pal Suh, MD, PhD, Hoon Kook, MD, PhD, Dong-Wook Ryang, MD, PhD, Myung-Geun Shin, MD, PhD

Blood (2013) 122 (21): 1221.

https://doi.org/10.1182/blood.V122.21.1221.1221

Published: 2013

Journal Articles

The Bleeding Defect Exhibited by Aryl Hydrocarbon Receptor-Null Mice Is Due to Defective Collagen-Dependent Outside-in Signaling

Stephan C. Lindsey, PhD, Jinlin Jiang, Donna Woulfe, PhD, Eleftherios T. Papoutsakis, PhD

Blood (2012) 120 (21): 3294.

https://doi.org/10.1182/blood.V120.21.3294.3294

Published: 2012

Journal Articles

In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells

Qin Tang, MS, Ahn Yong-Oon, Ph.D., Peter Southern, Ph.D., Bruce R. Blazar, MD, Jeffrey S Milller, MD, Michael Verneris, MD

Blood (2010) 116 (21): 108.

https://doi.org/10.1182/blood.V116.21.108.108

Published: 2010

Journal Articles

ARNT Mediates Chemotherapy Resistance by Modulating the Response to Oxidative Stress in AML Cells.

Richard A. Wells, MD, DPhil, Chunhong Gu, PhD, Joelle dela Paz, MSc

Blood (2009) 114 (22): 2737.

https://doi.org/10.1182/blood.V114.22.2737.2737

Published: 2009

Journal Articles

Stapled Peptides: Leveraging the BH3 α-Helix to Create a New Class of Drugs to Treat Hematological Malignancies

Rosana Kapeller, Jiawen Han, Kaiming Sun, Pranoti Gangurde, Nori Kawahata, Matt Iadanza, Vincent Guerlevais, Jim Horstick, Justin Noehre, Allen Annis, Larry Licklider, Huw M. Nash, Andrew Kung, Tomi K. Sawyer

Blood (2008) 112 (11): 2929.

https://doi.org/10.1182/blood.V112.11.2929.2929

Published: 2008

Journal Articles

A Stapled BIM BH3 Helix Overcomes the MCL-1-Mediated Apoptotic Blockade of Refractory Hematologic Cancers

James L. Labelle, MD, PhD, Chelsea E. Lawrence, Gregory H. Bird, Ph.D., Loren D. Walensky, M.D., Ph.D.

Blood (2008) 112 (11): 862.

https://doi.org/10.1182/blood.V112.11.862.862

Published: 2008

Journal Articles

A Stapled p53 Helix Targets HDMX to Overcome Nutlin-3 Resistance and Reactivate the p53 Tumor Suppressor Pathway in Cancer

Federico Bernal, Ph.D., Mark Wade, Ph.D., Amy M. Silverstein, Gregory L. Verdine, Ph.D., Geoffrey M. Wahl, Ph.D., Loren D. Walensky, M.D., Ph.D.

Blood (2008) 112 (11): 2645.

https://doi.org/10.1182/blood.V112.11.2645.2645

Published: 2008

Journal Articles

Pharmacologic Replacement of BIM BH3 Reactivates Apoptosis in Hematologic Cancer and Lymphoproliferative Disease.

James L. LaBelle, MD, PhD, Jill K. Fisher, Samuel G. Katz, MD, PhD, Gregory H. Bird, PhD, Chelsea E. Lawrence, Amy M. Silverstein, Loren D. Walensky, MD, PhD

Blood (2007) 110 (11): 524.

https://doi.org/10.1182/blood.V110.11.524.524

Published: 2007

Journal Articles

Direct Inhibition of the Notch Transactivation Complex with Synthetic Constrained Peptides in T-Cell Acute Lymphoblastic Leukemia.

Raymond Moellering, BA, Melanie Cornejo, B.A., Jennifer Rocknik, B.A., Michael Hancock, Ph.D., Christina DelBianco, Ph.D., Stephen Blacklow, M.D., Ph.D., Gary Gilliland, M.D., Ph.D., Gregory Verdine, Ph.D., James Bradner, M.D.

Blood (2007) 110 (11): 2819.

https://doi.org/10.1182/blood.V110.11.2819.2819

Published: 2007

Journal Articles

Selective Targeting of the p53-hDM2 Interaction Using Hydrocarbon-Stapled p53 Peptides.

Federico Bernal, PhD, Loren D. Walensky, MD,PhD, Andrew F. Tyler, Stanley J. Korsmeyer, MD, Gregory L. Verdine, PhD

Blood (2006) 108 (11): 525.

https://doi.org/10.1182/blood.V108.11.525.525

Published: 2006

Journal Articles

Anti-Leukemic Potency of Stapled BH3 Helices Correlates with Their Capacity for Bifunctional Activation of Apoptotic Pathways.

Loren D. Walensky, MD, PhD, Kenneth Pitter, Joel G. Morash, Gregory L. Verdine, PhD, Stanley J. Korsmeyer, MD

Blood (2006) 108 (11): 711.

https://doi.org/10.1182/blood.V108.11.711.711

Published: 2006

Journal Articles

Fine and Ultrafine Particles Differentially Affect the PFA-100-Times and Raise Proinflammatory Cytokines in Human Blood.

Marc Forestier, PhD, Linda Buechi, Corinna Hermann, PhD, Thomas Hartung, MD, Juerg H. Beer, MD

Blood (2005) 106 (11): 2640.

https://doi.org/10.1182/blood.V106.11.2640.2640

Published: 2005

NARROW

Triple Degradation of BTK, IKZF1 and IKZF3 in B-Cell Malignancies

Spatial Structure of Plasma Coagulation Factor XIII and Changes with Activation

Quantitative Structural Characterization of Fibrinogen's αC Regions in Fibrin Monomers and Oligomers

Phenotype Does Not Always Equal Function: HDAC Inhibitors and UM171, but Not SR1, Lead to Rapid Upregulation of CD90 on Non-Engrafting CD34+CD90-Negative Human Cells

A Novel Megakaryocyte-Based Screening System Identifies Compounds That Promote Megakaryocyte Maturation and Platelet Production in Vitro

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

Profiling Of Polycyclic Aromatic Hydrocarbons-Induced Genotoxicity In Peripheral Blood Stem Cells and Bone Marrow Mesenchymal Stem Cells

The Bleeding Defect Exhibited by Aryl Hydrocarbon Receptor-Null Mice Is Due to Defective Collagen-Dependent Outside-in Signaling

In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells

ARNT Mediates Chemotherapy Resistance by Modulating the Response to Oxidative Stress in AML Cells.

Stapled Peptides: Leveraging the BH3 α-Helix to Create a New Class of Drugs to Treat Hematological Malignancies

A Stapled BIM BH3 Helix Overcomes the MCL-1-Mediated Apoptotic Blockade of Refractory Hematologic Cancers

A Stapled p53 Helix Targets HDMX to Overcome Nutlin-3 Resistance and Reactivate the p53 Tumor Suppressor Pathway in Cancer

Pharmacologic Replacement of BIM BH3 Reactivates Apoptosis in Hematologic Cancer and Lymphoproliferative Disease.

Direct Inhibition of the Notch Transactivation Complex with Synthetic Constrained Peptides in T-Cell Acute Lymphoblastic Leukemia.

Selective Targeting of the p53-hDM2 Interaction Using Hydrocarbon-Stapled p53 Peptides.

Anti-Leukemic Potency of Stapled BH3 Helices Correlates with Their Capacity for Bifunctional Activation of Apoptotic Pathways.

Fine and Ultrafine Particles Differentially Affect the PFA-100-Times and Raise Proinflammatory Cytokines in Human Blood.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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