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Journal Articles

Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN)

Monika M Kutyna, MSc, Amilia Wee, BSc (Hons), Sharon Paton, BSc, Dimitrios Cakouros, PhD, Agnes Arthur, PhD, Rakchha Chhetri, MBBS, Deepak Singhal, MBBS, MD FRACP, FRCPA, Stan Gronthos, PhD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD

Blood (2019) 134 (Supplement_1): 1694.

https://doi.org/10.1182/blood-2019-126457

Published: 2019

Journal Articles

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Yuqi Zhu, Ye Yang, PhD, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2019) 134 (Supplement_1): 3102.

https://doi.org/10.1182/blood-2019-123815

Published: 2019

Journal Articles

Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma

Marita Westhrin, Vlado Kovcic, Albert Bondt, Stephanie Holst, Zejian Zhang, Anders Sundan, PhD, Tobias S. Slørdahl, Anders Waage, MD PhD, Manfred Wuhrer, Therese Standal

Blood (2019) 134 (Supplement_1): 4324.

https://doi.org/10.1182/blood-2019-122542

Published: 2019

Journal Articles

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

Balkrishan Sharma, PhD, Duaa Mureb, BS, Sumit Murab, PhD, Leah A. Rosenfeldt, BS, Brenton J Francisco, MD, Alexander A Boucher, MD, Rachel Cantrell, BS, Jacob Mast, Matthew J. Flick, PhD, Patrick W Whitlock, MD, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 1111.

https://doi.org/10.1182/blood-2019-130497

Published: 2019

Journal Articles

Genetic Dissection of p53 Driven Senescence of Bone Marrow Mesenchymal Cells in Acute Myeloid Leukemia

Rasoul Pourebrahim, MD PhD, Peter P. Ruvolo, PhD, Steven M. Kornblau, MD, Carlos E. Bueso-Ramos, MD PhD, Michael Andreeff, MD PhD

Blood (2018) 132 (Supplement 1): 2625.

https://doi.org/10.1182/blood-2018-99-117585

Published: 2018

Journal Articles

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

Charlotte Hellmich, MBBChir, BSc, MRCP, Amina Abdul-Aziz, MSc, Yu Sun, BSc, MSc, Christopher Richard Marlein, BSc, Eoghan Forde, Rachel E Piddock, BSc, Manar Shafat, MSc, Adam Morfakis, BSc, Mehta Tarang, Federica Di Palma, Christopher Ingham, Angela Collins, MBBS, Anna Haestier, Bsc, PgD MBBS, MRCOG, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2018) 132 (Supplement 1): 2770.

https://doi.org/10.1182/blood-2018-99-115274

Published: 2018

Journal Articles

Efficacy Evaluation of Liver-Directed Gene Therapy in Fabry Mice

Azadeh Kia, PhD, Jenny McIntosh, PhD, Cecilia Rosales, PhD, Paniz Hosseini, Rose Sheridan, Justyna Spiewak, Kevin Mills, Romuald Corbau, PhD, Amit C Nathwani, MD PhD

Blood (2018) 132 (Supplement 1): 2209.

https://doi.org/10.1182/blood-2018-99-116632

Published: 2018

Journal Articles

Immune Clearance of Senescent Cells Via Activation of Endogenous Retroviruses and the Viral Recognition Pathway

Devi Thiagarajan, Stephen Capone, BS, Kwasi Connor, Pradeep K Aggarwal, Xin Li, Kaijin Wu, Anthony Colombo, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD

Blood (2017) 130 (Supplement 1): 3576.

https://doi.org/10.1182/blood.V130.Suppl_1.3576.3576

Published: 2017

Journal Articles

Therapy‐Induced Senescence Is a Predictor of Treatment Outcome in Acute Myeloid Leukemia

Martin Schönlein, J. Henry M. Däbritz, Dorothy Ngo-Yin Fan, Jana Ihlow, Rolf Schwarzer, Binje Vick, Karsten Spiekermann, Thomas Burmeister, Jörg Westermann, Irmela Jeremias, Clemens A. Schmitt

Blood (2017) 130 (Supplement 1): 1393.

https://doi.org/10.1182/blood.V130.Suppl_1.1393.1393

Published: 2017

Journal Articles

Acute Myeloid Leukaemia Induces p16 Driven Senescence in the Bone Marrow Microenvironment to Support Their Proliferation and Survival

Amina Abdul-Aziz, MSc, Manar Shafat, MSc, Rachel Piddock, BSc, Christopher Marlein, BSc, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc

Blood (2017) 130 (Supplement 1): 1394.

https://doi.org/10.1182/blood.V130.Suppl_1.1394.1394

Published: 2017

Journal Articles

Attenuation of CXCR4/SDF-1 Axis in Bone Marrow Mesenchymal Stromal Cells Impairs Hematopoietic Niche Activity and Promotes Stem Cell Aging

Pratibha Singh, PhD, Melissa A Kacena, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2017) 130 (Supplement 1): 92.

https://doi.org/10.1182/blood.V130.Suppl_1.92.92

Published: 2017

Journal Articles

Aurora A Kinase As a Promising Therapeutic Target in Philadelphia Chromosome Positive Leukemia Cells

Seiichi Okabe, MD PhD, Tetsuzo Tauchi, MD, Yuko Tanaka, MD PhD, Kazuma Ohyashiki, MD PhD

Blood (2017) 130 (Supplement 1): 3828.

https://doi.org/10.1182/blood.V130.Suppl_1.3828.3828

Published: 2017

Journal Articles

N-Acetyl-L-Cysteine Improves Mesenchymal Stem Cell Function in Prolonged Isolated Thrombocytopenia Post-Allotransplant

Yuan Kong, Song Yang, Fei-Fei Tang, Hong-Yan Zhao, Yu-Hong Chen, Wei Han, Chen-Hua Yan, Yu Wang, Xiaohui Zhang, MD, Xiao-Jun Huang, MD

Blood (2017) 130 (Supplement 1): 4449.

https://doi.org/10.1182/blood.V130.Suppl_1.4449.4449

Published: 2017

Journal Articles

HUWE1 Inhibition As a Therapeutic Strategy to Target MYC in MM

Lisa J Crawford, BSc, PhD, Dharminder Chauhan, PhD, Alexandra E Irvine, PhD FRCPath

Blood (2017) 130 (Supplement 1): 3077.

https://doi.org/10.1182/blood.V130.Suppl_1.3077.3077

Published: 2017

Journal Articles

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Gang Xiao, PhD, Chao Hong, PhD, Huimin Geng, PhD, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 882.

https://doi.org/10.1182/blood.V130.Suppl_1.882.882

Published: 2017

Journal Articles

Overexpression of BCL9, a Wnt/β-Catenin Transcriptional Co-Activator, in Transgenic Mice Promotes Spontaneous Development of B-Cell Malignancies

Tomasz Sewastianik, PhD, Jianjun Zhao, MD PhD, Meng Jiang, MD, Peter S. Dennis, BS, Myles Brown, MD, Kwok Wong, MD, Ruben D. Carrasco, MD PhD

Blood (2016) 128 (22): 441.

https://doi.org/10.1182/blood.V128.22.441.441

Published: 2016

Journal Articles

Acute Myeloid Leukemia Cells Resist Chemotherapy through a Reversible Senescence-like State Maintaining Repopulation Potential

Cihangir Duy, PhD, Matt Teater, M.S., Francine E. Garrett-Bakelman, MD PhD, Martin Carroll, MD, Ari Melnick, MD

Blood (2016) 128 (22): 582.

https://doi.org/10.1182/blood.V128.22.582.582

Published: 2016

Journal Articles

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Deborah Ingenhag, MSc, Franziska Auer, MSc, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2016) 128 (22): 1539.

https://doi.org/10.1182/blood.V128.22.1539.1539

Published: 2016

Journal Articles

Activity of the Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Copanlisib, As a Single Agent and in Combination with Carfilzomib in Multiple Myeloma

Sarah M Larson, MD, Mao Yu Peng, PhD, Andrae Vandross, MD, Monica Mead, MD BS, Zoe Fuchs, Dylan Conklin, PhD, Erika Von Euw, PhD BS, Dennis J. Slamon, MD PhD

Blood (2016) 128 (22): 5665.

https://doi.org/10.1182/blood.V128.22.5665.5665

Published: 2016

Journal Articles

Alisertib-Induced Polyploidy and Senescence in DH/DP-DLBCL Is Abrogated By Synthetic Lethal Interactions with Ibrutinib and Rituximab

Shariful Islam, MS, Wenqing Qi, PhD, Carla Morales, B.S., Laurence Cooke, M.S., Manjari Pandey, MD, Catherine M. Spier, MD, Daruka Mahadevan, MD PhD

Blood (2016) 128 (22): 5397.

https://doi.org/10.1182/blood.V128.22.5397.5397

Published: 2016

NARROW

Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN)

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

Genetic Dissection of p53 Driven Senescence of Bone Marrow Mesenchymal Cells in Acute Myeloid Leukemia

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

Efficacy Evaluation of Liver-Directed Gene Therapy in Fabry Mice

Immune Clearance of Senescent Cells Via Activation of Endogenous Retroviruses and the Viral Recognition Pathway

Therapy‐Induced Senescence Is a Predictor of Treatment Outcome in Acute Myeloid Leukemia

Acute Myeloid Leukaemia Induces p16 Driven Senescence in the Bone Marrow Microenvironment to Support Their Proliferation and Survival

Attenuation of CXCR4/SDF-1 Axis in Bone Marrow Mesenchymal Stromal Cells Impairs Hematopoietic Niche Activity and Promotes Stem Cell Aging

Aurora A Kinase As a Promising Therapeutic Target in Philadelphia Chromosome Positive Leukemia Cells

N-Acetyl-L-Cysteine Improves Mesenchymal Stem Cell Function in Prolonged Isolated Thrombocytopenia Post-Allotransplant

HUWE1 Inhibition As a Therapeutic Strategy to Target MYC in MM

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Overexpression of BCL9, a Wnt/β-Catenin Transcriptional Co-Activator, in Transgenic Mice Promotes Spontaneous Development of B-Cell Malignancies

Acute Myeloid Leukemia Cells Resist Chemotherapy through a Reversible Senescence-like State Maintaining Repopulation Potential

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Activity of the Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Copanlisib, As a Single Agent and in Combination with Carfilzomib in Multiple Myeloma

Alisertib-Induced Polyploidy and Senescence in DH/DP-DLBCL Is Abrogated By Synthetic Lethal Interactions with Ibrutinib and Rituximab

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American Society of Hematology

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ASH Publications

American Society of Hematology

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