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Journal Articles

Nucleolin As a Survival Predictor in Acute Lymphoblastic Leukemia and Its Promotion to Drug Resistance By ERK Pathway

Jianda Hu, Prof MDPhD, Yanxin Chen, MDPhD, Minhui Lin, PhD, Yingyu Chen, PhD, Ting Yang

Blood (2017) 130 (Supplement 1): 1291.

https://doi.org/10.1182/blood.V130.Suppl_1.1291.1291

Published: 2017

Journal Articles

Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation

Janine Schmidt, Joan Enric Ramis-Zaldivar, Ferran Nadeu, Blanca Gonzalez-Farre, Alba Navarro, Caoimhe Egan, Ivonne Aidee Montes-Mojarro, Teresa Marafioti, Jose Cabeçadas, Jon van der Walt, Stefan Dojcinov, Andreas Rosenwald, German Ott, Irina Bonzheim, Falko Fend, Elias Campo, Elaine S. Jaffe, Itziar Salaverria, Leticia Quintanilla-Martinez

Blood (2017) 130 (3): 323–327.

https://doi.org/10.1182/blood-2017-03-776278

Published: 2017

Includes: Supplemental data

Journal Articles

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Jens Lichtenberg, PhD, Elisabeth F. Heuston, PhD, Stacie M. Anderson, NIH Intramural Sequencing Center, Cheryl A. Keller, PhD, Ross C. Hardison, PhD, David M. Bodine, PhD

Blood (2016) 128 (22): 3868.

https://doi.org/10.1182/blood.V128.22.3868.3868

Published: 2016

Journal Articles

Kras Is Critical for CD8 T Cell Antiviral Function

Yuhong Chen, PhD, Yongwei Zheng, PhD, Xiaona You, PhD, Gang Xin, PhD, Mei Yu, PhD, Guoping Fu, PhD, Fen Zhou, Wen Zhu, Weiguo Cui, PhD, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD

Blood (2015) 126 (23): 284.

https://doi.org/10.1182/blood.V126.23.284.284

Published: 2015

Journal Articles

Kras Is Critical for B Cell Lymphopoiesis

Yongwei Zheng, PhD, Yuhong Chen, PhD, Xiaona You, PhD, Mei Yu, PhD, Guoping Fu, PhD, Xinlin Su, Wen Zhu, Zhihong Wu, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD

Blood (2015) 126 (23): 3588.

https://doi.org/10.1182/blood.V126.23.3588.3588

Published: 2015

Journal Articles

Cassani B, Mirolo M, Cattaneo F, et al. Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. Blood . 2008;111(8): 4209-4219 .

Blood (2014) 123 (23): 3682.

https://doi.org/10.1182/blood-2014-04-572016

Published: 2014

Journal Articles

Somatic activating ARAF mutations in Langerhans cell histiocytosis

David S. Nelson, Willemijn Quispel, Gayane Badalian-Very, Astrid G. S. van Halteren, Cor van den Bos, Judith V. M. G. Bovée, Sara Y. Tian, Paul Van Hummelen, Matthew Ducar, Laura E. MacConaill, R. Maarten Egeler, Barrett J. Rollins

Blood (2014) 123 (20): 3152–3155.

https://doi.org/10.1182/blood-2013-06-511139

Published: 2014

Includes: Supplemental data

Journal Articles

Resveratrol Inhibits Myeloid Leukemia Cell Lines With JAK2V617F Via Both Inactivation Of The JAK/STAT Pathway and Upregulation Of The ERK Pathway

Ly Quoc Trung, MD, Luis J. Espinoza, MD, PhD, Dao T. T. An, MD, Shinji Nakao, MD, PhD

Blood (2013) 122 (21): 3854.

https://doi.org/10.1182/blood.V122.21.3854.3854

Published: 2013

Journal Articles

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34 + cells through the Raf/MEK/ERK pathway

Chutima Kumkhaek, Wulin Aerbajinai, Wenli Liu, Jianqiong Zhu, Naoya Uchida, Roger Kurlander, Matthew M. Hsieh, John F. Tisdale, Griffin P. Rodgers

Blood (2013) 121 (16): 3216–3227.

https://doi.org/10.1182/blood-2011-10-385252

Published: 2013

Includes: Supplemental data

Journal Articles

The p90RSK Inhibitor BI-D1870 Induces Apoptosis in CLL Cells

Andrew J Steele, PhD, Archibald G Prentice, MBChB, FRCP, FRCPath, Victoria Last, PhD, A. Victor Hoffbrand, DM, DSc, R G Wickremasinghe

Blood (2011) 118 (21): 2492.

https://doi.org/10.1182/blood.V118.21.2492.2492

Published: 2011

Journal Articles

Endogenous Oncogenic Nras Signaling Promotes Proliferative Exhaustion of Hematopoietic Stem Cells Through a Dose-Dependent Hyperactivation of ERK,

Jinyong Wang, PhD, Yangang Liu, Juan Du, Myung-Jeom Ryu, Erik A. Ranheim, MD, PhD, Jing Zhang

Blood (2011) 118 (21): 3997.

https://doi.org/10.1182/blood.V118.21.3997.3997

Published: 2011

Journal Articles

Oroxylin A Induce Differentiation and G0/G1 Phase Arrest of Acute Myeloid Leukemia (AML)Cells Via Effects on PPARγ/RXRα Heterodimers,

Hui Hui, Bao-An Chen, MD, PhD, Qing-long Guo

Blood (2011) 118 (21): 3635.

https://doi.org/10.1182/blood.V118.21.3635.3635

Published: 2011

Journal Articles

The Transcription Factor SCL/TAL-1 Plays a Positive Role in the Erythropoietic Differentiation Via MEK/ERK Pathway in EPO-Induced K562 Cell Line

Yuping Gong, Ruiqing Zhou, Ting Niu, M.D., Ph.D.

Blood (2011) 118 (21): 4799.

https://doi.org/10.1182/blood.V118.21.4799.4799

Published: 2011

Journal Articles

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

Takashi Yokoyama, Yohei Kanno, Yukari Yamazaki, Tomoko Takahara, Satoshi Miyata, Takuro Nakamura

Blood (2010) 116 (15): 2768–2775.

https://doi.org/10.1182/blood-2009-10-246264

Published: 2010

Includes: Supplemental data

Journal Articles

Development of Mek inhibition (MEK-I)-Based Therapeutic Strategies in Acute Myeloid Leukemia (AML)

Michele Milella, MD, Maria Rosaria Ricciardi, Paola Bergamo, MS, Maria Cristina Scerpa, PhD, Jacopo Gervasoni, MS, Maria Teresa Petrucci, MD, Sabina Chiaretti, MD, Simona Tavolaro, MS, Ludovica Ciuffreda, PhD, Samantha Decandia, Francesco Libotte, Stephen Lee Abrams, Linda S Steelman, BS., MS, Marina Konopleva, MD, PhD, Francesco Cognetti, MD, Robert Foa, Michael Andreeff, MD, PhD, James McCubrey, PhD, Agostino Tafuri

Blood (2008) 112 (11): 860.

https://doi.org/10.1182/blood.V112.11.860.860

Published: 2008

Journal Articles

Genetic Screening for Myeloma Cell Susceptibility to NK Cell Mediated Lysis Using Large Lentiviral shRNA Libraries

Roberto Bellucci, Ph.D, Hong-Nam Nguyen, Allison Martin, Anna Schinzel, Ph.D, John Daley, Steen Hansen, M.D., Ph.D, William C. Hahn, M.D., Ph.D, Jerome Ritz, M.D.

Blood (2008) 112 (11): 2900.

https://doi.org/10.1182/blood.V112.11.2900.2900

Published: 2008

Journal Articles

Overexpansion of Th17 and Th1/17 Cells in Patients with Myelodysplastic Syndrome

Elena E. Solomou, MD, PhD, A. Tsanaktsi, MD, V. Fertakis, K. Dallas, S. Karambina, M. Tiniakou, A. Kourakli, I. Micheva, A. P Andonopoulos, MD, FACP, S.N C Liossis, MD, P. Matsouka, MD, Nicholas Zoumbos, MD, PhD

Blood (2008) 112 (11): 2698.

https://doi.org/10.1182/blood.V112.11.2698.2698

Published: 2008

Journal Articles

UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

Alvaro A Elorza, PhD, Brigham B Hyde, Hanna Mikkola, MD, PhD, Sheila Collins, PhD, Orian S Shirihai, MD/PhD

Blood (2008) 112 (11): 5372.

https://doi.org/10.1182/blood.V112.11.5372.5372

Published: 2008

Journal Articles

Dendritic Cells, Generated and Matured, after Elutriation, in Clinical Grade Bags, Differ in Immune Functions When Compared to Classical DCs Generated in Plates.

Redouane Rouas, Haidar Akl, Bassam Badran, Larissa Di Pietrantonio, Hugues Duvillier, Philippe Martiat, Philippe Lewalle

Blood (2008) 112 (11): 1544.

https://doi.org/10.1182/blood.V112.11.1544.1544

Published: 2008

Journal Articles

Loss of Pak1 Corrects Multiple Gain of Function Phenotypes in Nf1+/ − Mast Cells.

Andrew McDaniel, D. Wade Clapp, M.D., J. Chernoff

Blood (2007) 110 (11): 236.

https://doi.org/10.1182/blood.V110.11.236.236

Published: 2007

NARROW

Nucleolin As a Survival Predictor in Acute Lymphoblastic Leukemia and Its Promotion to Drug Resistance By ERK Pathway

Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Kras Is Critical for CD8 T Cell Antiviral Function

Kras Is Critical for B Cell Lymphopoiesis

Cassani B, Mirolo M, Cattaneo F, et al. Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. Blood . 2008;111(8): 4209-4219 .

Somatic activating ARAF mutations in Langerhans cell histiocytosis

Resveratrol Inhibits Myeloid Leukemia Cell Lines With JAK2V617F Via Both Inactivation Of The JAK/STAT Pathway and Upregulation Of The ERK Pathway

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34 + cells through the Raf/MEK/ERK pathway

The p90RSK Inhibitor BI-D1870 Induces Apoptosis in CLL Cells

Endogenous Oncogenic Nras Signaling Promotes Proliferative Exhaustion of Hematopoietic Stem Cells Through a Dose-Dependent Hyperactivation of ERK,

Oroxylin A Induce Differentiation and G0/G1 Phase Arrest of Acute Myeloid Leukemia (AML)Cells Via Effects on PPARγ/RXRα Heterodimers,

The Transcription Factor SCL/TAL-1 Plays a Positive Role in the Erythropoietic Differentiation Via MEK/ERK Pathway in EPO-Induced K562 Cell Line

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

Development of Mek inhibition (MEK-I)-Based Therapeutic Strategies in Acute Myeloid Leukemia (AML)

Genetic Screening for Myeloma Cell Susceptibility to NK Cell Mediated Lysis Using Large Lentiviral shRNA Libraries

Overexpansion of Th17 and Th1/17 Cells in Patients with Myelodysplastic Syndrome

UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

Dendritic Cells, Generated and Matured, after Elutriation, in Clinical Grade Bags, Differ in Immune Functions When Compared to Classical DCs Generated in Plates.

Loss of Pak1 Corrects Multiple Gain of Function Phenotypes in Nf1+/ − Mast Cells.

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American Society of Hematology

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American Society of Hematology

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