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Journal Articles

PIG-a Gene Expression Deficiency Association with Reduced DNA Damage Checkpoint Response and Activation

Jeffrey J Pu, MD PhD, Shasha Lu, MD PhD, Matthew Nemesure, Emmanuel Kwame Teye, PhD, Emily Schleicher, George-Lucian Moldovan, PhD, Robert A. Brodsky, MD, Fangyuan Chen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3875.
https://doi.org/10.1182/blood-2018-99-119177
Published: 2018
Journal Articles

LNK (SH2B3) Deficiency Ameliorates Hematopoietic Stem Cell Defects in Fanconi Anemi

Joanna Balcerek, Jing Jiang, PhD, Qinqin Jiang, Kaosheng Lyu, PhD, Roger Greenberg, MD PhD, Wei Tong, PhD
Journal: Blood
Blood (2016) 128 (22): 2670.
https://doi.org/10.1182/blood.V128.22.2670.2670
Published: 2016
Journal Articles

Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate

Matteo Marchesini, PhD, Yamini Ogoti, Irene Ganan-Gomez, PhD MSc, Yue Wei, PhD, Carlos E. Bueso-Ramos, Guillermo Garcia-Manero, MD, Ronald A. DePinho, Simona Colla, PhD
Journal: Blood
Blood (2015) 126 (23): 1156.
https://doi.org/10.1182/blood.V126.23.1156.1156
Published: 2015
Journal Articles

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

Han Liu, Shugaku Takeda, Rakesh Kumar, Todd Westergard, Tej Pandita, Emily Cheng, MD, PhD, James J.-D. Hsieh, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 450.
https://doi.org/10.1182/blood.V114.22.450.450
Published: 2009
Journal Articles

High Prevalence of TERT Mutations in Chronic Lymphocytic Leukemia

Mark Hills, Alexander Roeth, MD, Holger Nückel, MD, Doug Horsman, Jan Duerig, Randy D. Gascoyne, MD, Peter M. Lansdorp, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3126.
https://doi.org/10.1182/blood.V112.11.3126.3126
Published: 2008
Journal Articles

The Role of MLL in DNA Damage Checkpoint and Its Implication in Leukemogenesis

Han Liu, PhD, Todd D Westergard, David Y Chen, Emily H.-Y. Cheng, MD, PhD, James J.-D. Hsieh, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 5332.
https://doi.org/10.1182/blood.V112.11.5332.5332
Published: 2008
Journal Articles

BCL6 Attenuates DNA Damage Sensing in Normal and Malignant B-Cells by Directly Repressing ATR.

Stella M. Ranuncolo, MD, PhD, Jose M. Polo, MS, Jamil Dierov, PhD, Rita Shaknovich, MD, Martin Carroll, MD, Ari M. Melnick, MD
Journal: Blood
Blood (2005) 106 (11): 157.
https://doi.org/10.1182/blood.V106.11.157.157
Published: 2005
Journal Articles

A Role for NIPA in DNA Damage Response.

Christine von Klitzing, Florian Bassermann, MD, Stephan W. Morris, MD, Christian Peschel, MD, Justus Duyster, MD
Journal: Blood
Blood (2004) 104 (11): 1265.
https://doi.org/10.1182/blood.V104.11.1265.1265
Published: 2004
Journal Articles

The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21 waf-1

Brief Report
Charlie R. Mantel, Stephen E. Braun, Younghee Lee, Young-June Kim, Hal E. Broxmeyer
Journal: Blood
Blood (2001) 97 (5): 1505–1507.
https://doi.org/10.1182/blood.V97.5.1505
Published: 2001