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Journal Articles

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Yu Sun, BSc, MSc, PhD, Jayna J Mistry, BSc, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Christopher R Marlein, PhD, Anna Haestier, Cesar A. Gomez, MD PhD FRCPath, Christopher J Morris, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 689.
https://doi.org/10.1182/blood-2019-128268
Published: 2019
Journal Articles

Phase-I Study of ETA Receptor Antagonist Ambrisentan in Sickle Cell Disease

Abdullah Kutlar, MD, Jennifer Pollock, PhD, Steffen E. Meiler, MD, Ryan Harris, PhD CEP, FACSM, Xu Hongyan, PhD, Leigh Wells, MSN, Latanya Bowman, RN, Sharon Jones, BS, David M. Pollock, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 617.
https://doi.org/10.1182/blood-2019-130036
Published: 2019
Journal Articles

Updated Results from the German Mpnsg-0212 Combination Trial: Ruxolitinib Plus Pomalidomide in Myelofibrosis with Anemia

Frank Stegelmann, MD, Steffen Koschmieder, Susanne Isfort, Andreas Hochhaus, MD, Florian H. Heidel, Holger Hebart, Markus Bangerter, Denise Wolleschak, Christoph Scheid, MD, Joachim R Göthert, PD, MD, Philippe Schafhausen, Thomas Kindler, MD, Markus P. Radsak, MD, Robert Möhle, MD, Cornelius Waller, Nikolas von Bubnoff, Andreas Reiter, Hartmut Döhner, MD, Martin Griesshammer, MD, Konstanze Döhner
Journal: Blood
Blood (2019) 134 (Supplement_1): 672.
https://doi.org/10.1182/blood-2019-127859
Published: 2019
Journal Articles

Correcting Rare Blood Disorders Using Coagulation Factors Produced In Vivo By Shielded Living Therapeutics TM Products

Guillaume Carmona, PhD, Lauren Barney, PhD, Jared Sewell, PhD, Ryan Newman, Christine Carroll, Michael Beauregard, Janet Huang, MSc, Richard W Heidebrecht, Jr., PhD, Deya Corzo, MD, David Moller, MD, Devyn Smith, PhD, David Peritt, PhD, Rogerio Vivaldi, MD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 2065.
https://doi.org/10.1182/blood-2019-127050
Published: 2019
Journal Articles

A Biophysically Defined MSC Subpopulation for Enhanced Homing and Immunosuppression

Zhiyong Poon, Xiubo Fan, PhD, Alice Cheung, PhD, Sudipto Bari, PhD, William YK Hwang, MBBS, FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 2078.
https://doi.org/10.1182/blood-2019-126683
Published: 2019
Journal Articles

Economic Burden of Bronchiolitis Obliterans Syndrome (BOS) Following Allogeneic Hematopoietic Stem Cell Transplant (alloHSCT) in Patients with Commercial Insurance in the United States

Naomi Sacks, PhD, Bridget Healey, MPH, Philip Cyr, MPH, Katharine Batt, MD MSc, Noreen Roth Henig, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3410.
https://doi.org/10.1182/blood-2019-127197
Published: 2019
Journal Articles

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Jevgenia Zilberman-Rudenko, Hiroshi Deguchi, MD PhD, Mohammed Hayat, Meenal Shukla, PhD, Jennifer Nagrampa Orje, Zihan Guo, Tine Wyseure, PhD, Laurent O Mosnier, Owen J T McCarty, PhD, Zaverio M. Ruggeri, MD, John H. Griffin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3632.
https://doi.org/10.1182/blood-2019-129312
Published: 2019
Journal Articles

Acute Myeloid Leukemia Export Mitochondria in Extracellular Vesicles Which Induces Pro-Tumoral Changes in Bone Marrow Macrophages

Jamie A Moore, BSc, MSc, Jayna J Mistry, BSc, Rebecca H Horton, Charlotte Hellmich, MBBChir, Adam Pattinson, MSc, BSc, Adam Morfakis, BSc, Yu Sun, BSc, MSc, PhD, Matthew Lawes, MD, Christopher J Morris, PhD, Anna Haestier, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1427.
https://doi.org/10.1182/blood-2019-128447
Published: 2019
Journal Articles

High-Throughput Immunofluorescence and Electron Tomography to Characterize Centrosomal Aberrations in Plasma Cell Neoplasia

Tobias Dittrich, MD, Martin Schorb, Isabella Haberbosch, MD, Elena Bausch, PhD, Mandy Börmel, Marco Cosenza, PhD, Hartmut Goldschmidt, MD, Carsten Müller-Tidow, MD, Marc S Raab, MD PhD, Ute Hegenbart, MD, Stefan O. Schönland, MD, Yannick Schwab, PhD, Alwin Krämer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3077.
https://doi.org/10.1182/blood-2019-130713
Published: 2019
Journal Articles

A Pilot Study of Brentuximab Vedotin Combined with AVD Chemotherapy and Radiotherapy in Patients with Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma

Anita Kumar, MD, Carla Casulo, Ranjana H Advani, MD, Lihua E Budde, MD PhD, Paul M. Barr, MD, Connie Lee Batlevi, MD PhD, Philip Caron, MD PhD, Louis S. Constine, MD, Savita Dandapani, MD PhD, Esther Drill, PhD, Pamela Drullinsky, MD, Jonathan W. Friedberg, MD, Clare Grieve, BA, Audrey Hamilton, MD, Paul A. Hamlin, MD, Richard T Hoppe, MD, Steven M. Horwitz, MD, Matthew J Matasar, MD, Susan Jennifer McCall, NP, Alison J. Moskowitz, MD, Ariela Noy, MD, Maria Lia Palomba, MD, Heiko Schoder, MD, David J. Straus, MD, Shreya Vemuri, Joanna C Yang, MD MPH, Anas Younes, MD, Andrew D. Zelenetz, MD PhD, Joachim Yahalom, MD, Craig H. Moskowitz
Journal: Blood
Blood (2019) 134 (Supplement_1): 2834.
https://doi.org/10.1182/blood-2019-123150
Published: 2019
Journal Articles

Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

Frank Del Greco, MBA, Linda Neuman, MD, Howard Levy, PhD MBBChir, Jill Reckless, Tom Knudsen, PhD DVM, Grant E. Blouse, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2420.
https://doi.org/10.1182/blood-2019-128971
Published: 2019
Journal Articles

Biomarkers of Cardiopulmonary, Renal, and Liver Dysfunction in an Adult Sickle Cell Disease Cohort

Xu Zhang, PhD, Binal N. Shah, Roberto Machado, MD, Santosh L. Saraf, MD, Victor R Gordeuk, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3574.
https://doi.org/10.1182/blood-2019-131813
Published: 2019
Journal Articles

Efficient Ex Vivo Expansion of Highly Purified Human Umbilical Cord Blood-Derived Very Small CD34 + lin - CD45 - Stem Cells into Functional Endothelial Cells in Vitro in Chemically Identified, Feeder Layer-Free Medium Supplemented with Nicotinamide

Alison Domingues, MS, Kamila Bujko, MS, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 4882.
https://doi.org/10.1182/blood-2019-125819
Published: 2019
Journal Articles

A Fully Automated Measurement of Total Metabolic Tumor Burden in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma

Skander Jemaa, MS, Jill Fredrickson, PhD, Alexandre Coimbra, PhD, Richard AD Carano, PhD, Tarec Christoffer C. El-Galaly, MD, Andrea Knapp, PhD, Tina G Nielsen, MD PhD, Deniz Sahin, BSc, Thomas Bengtsson, PhD, Alex de Crespigny, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4666.
https://doi.org/10.1182/blood-2019-124793
Published: 2019
Journal Articles

Standardization of Schistocyte Identification and Quantitation for the Diagnosis of Thrombotic Microangiopathic Anemia at University of Cincinnati Medical Center

Pooja Agarwal, MD, Rafiullah Khan, MD MBA, Kristina Brannock, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4796.
https://doi.org/10.1182/blood-2019-125174
Published: 2019
Journal Articles

A Machine Learning Algorithm to Improve Risk Assessment for Patients with Sickle Cell Disease

Vandana Sachdev, MD, Yuan Gu, PhD, James Nichols, RN, Wen Li, RCS, Stanislav Sidenko, RCS, Darlene Allen, MT(ASCP), Colin Wu, PhD, Swee Lay Thein, DSc, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 893.
https://doi.org/10.1182/blood-2019-125846
Published: 2019
Journal Articles

Beyond PD-1: Investigating the Therapeutic Potential of TIGIT Blockade in DLBCL

Nicole Sunseri, MD PhD, Xiufen Chen, PhD, Noemie Wald, PhD, Julie Preillon, PhD, Sonali M. Smith, MD, Gregory Driessens, PhD, Justin Kline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 391.
https://doi.org/10.1182/blood-2019-131493
Published: 2019
Journal Articles

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Tine Wyseure, PhD, Niels Behrendt, Annette von Drygalski, MD PharmD, Laurent O Mosnier
Journal: Blood
Blood (2019) 134 (Supplement_1): 158.
https://doi.org/10.1182/blood-2019-128723
Published: 2019
Journal Articles

Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell Resolution

Shu Sun, BS, Chen Jin, PhD, Yueying Li, MD, Jia Si, Yueli Cui, Matthew T. Rondina, MD, Fuchou Tang, PhD, Qian-fei Wang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 275.
https://doi.org/10.1182/blood-2019-129471
Published: 2019
Journal Articles

EPCR Deficiency Prevents Development of Hemophilic Arthropathy

Jhansi Magisetty, PhD MSc, Usha Pendurthi, PhD, Charles T. Esmon, PhD, L. Vijaya Mohan Rao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 159.
https://doi.org/10.1182/blood-2019-124972
Published: 2019