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Journal Articles

Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing

Christos Georgiadis, PhD, Jane Rasaiyaah, PhD, Soragia Athina Gkazi, PhD, Roland Preece, Annie Etuk, PhD, Abraham Christi, Waseem Qasim, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3219.
https://doi.org/10.1182/blood-2019-130057
Published: 2019
Journal Articles

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara Mclennan, Remco M. Hoogenboezem, François G. Kavelaars, Stefan Fröhling, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, Bob Löwenberg, Andrew W. Roberts, Peter J. M. Valk, Ian J. Majewski
Journal: Blood
Blood (2018) 132 (14): 1526–1534.
https://doi.org/10.1182/blood-2018-05-852566
Published: 2018
Includes: Supplemental data
Journal Articles

DNMT3A Mutations Enhance CpG Mutagenesis through Deregulation of the Active DNA Demethylation Pathway

Mathijs A. Sanders, PhD, Annelieke Zeilemaker, Adil al Hinai, Remco Hoogenboezem, François G. Kavelaars, BSc, Melissa Rijken, Eric M.J. Bindels, PhD, Bob Löwenberg, MD PhD, Peter J.M. Valk, PhD
Journal: Blood
Blood (2016) 128 (22): 1076.
https://doi.org/10.1182/blood.V128.22.1076.1076
Published: 2016
Journal Articles

APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair

Roni Nowarski, Ofer I. Wilner, Ori Cheshin, Or D. Shahar, Edan Kenig, Leah Baraz, Elena Britan-Rosich, Arnon Nagler, Reuben S. Harris, Michal Goldberg, Itamar Willner, Moshe Kotler
Journal: Blood
Blood (2012) 120 (2): 366–375.
https://doi.org/10.1182/blood-2012-01-402123
Published: 2012
Includes: Supplemental data
Journal Articles

SGI-110, a Novel Second Generation Potent DNA Methylation Inhibitor, In Development for the Treatment of MDS and AML. Preclinical Safety, Pharmacokinetics, and DNA Methylation Results of a Low Volume Subcutaneous (SC) Formulation

Jason Scholl, PhD, Rajashree Joshi-Hangal, PhD, Roger Inloes, PhD, Chongtie Shi, PhD, Pietro Taverna, PhD, Gavin S. Choy, PharmD, MBA, Sanjeev Redkar, PhD, Mohammad Azab, MD, MSC, MBA
Journal: Blood
Blood (2010) 116 (21): 1872.
https://doi.org/10.1182/blood.V116.21.1872.1872
Published: 2010
Journal Articles

Response: Cautious interpretation of assessment of AID variant activities using cells with endogenous AID expression

Xiaosheng Wu, Diane F. Jelinek
Journal: Blood
Blood (2009) 113 (8): 1864.
https://doi.org/10.1182/blood-2008-11-187732
Published: 2009
Journal Articles

Pharmacodynamic (PD) Analyses of Asparagine (Asn) Deamination and Asn Input (Imax) in Serum of Pediatric Patients with Standard Risk Acute Lymphoblastic Leukemia (SR ALL) Receiving Native or Pegylated E. Coli Asparaginases (ASNase) (CCG-1962).

Vassilios I. Avramis, Ph.D., Eduard H. Panosyan, M.D., Cecilia H. Fu, M.D., Linda C. Stork, M.D., Paul S. Gaynon, M.D.
Journal: Blood
Blood (2004) 104 (11): 2082.
https://doi.org/10.1182/blood.V104.11.2082.2082
Published: 2004
Journal Articles

Pharmacokinetics and Pharmacodynamics of Three Asparaginases in Pediatric Patients with Higher Risk Acute Lymphoblastic Leukemia: A Report from CCG-1961.

Eduard H. Panosyan, M.D., Nita L. Seibel, M.D., Rita S. Grigoryan, M.D., Ioannis A. Avramis, B.S., Jon D. Jaques, Lawrence J. Ettinger, M.D., Paul S. Gaynon, M.D., Harland N. Sather, Ph.D., Janet Franklin, M.D., Fu Cecilia, M.D., Stuart E. Siegel, M.D., Howard J. Fingert, M.D., Vassilios I. Avramis, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2745.
https://doi.org/10.1182/blood.V104.11.2745.2745
Published: 2004