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Journal Articles

FXII inhibition: multipronged benefits

Helen Philippou
Journal: Blood
Blood (2021) 138 (2): 107–109.
https://doi.org/10.1182/blood.2021011032
Published: 2021
Journal Articles

T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis

Vandana Chaturvedi, Rebecca A. Marsh, Adi Zoref-Lorenz, Erika Owsley, Vijaya Chaturvedi, Trung C. Nguyen, Jordana R. Goldman, Michael M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Michael Jeng, Ahmed Naqvi, Carl E. Allen, Hector R. Wong, Michael B. Jordan
Journal: Blood
Blood (2021) 137 (17): 2337–2346.
https://doi.org/10.1182/blood.2020009499
Published: 2021
Includes: Supplemental data
Journal Articles

One-two punch of cytokine storm syndrome

Randy Q. Cron
Journal: Blood
Blood (2020) 136 (6): 645–646.
https://doi.org/10.1182/blood.2020007159
Published: 2020
Journal Articles

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

Lauren K. Meyer, Katherine C. Verbist, Sabrin Albeituni, Brooks P. Scull, Rachel C. Bassett, Alexa N. Stroh, Heather Tillman, Carl E. Allen, Michelle L. Hermiston, Kim E. Nichols
Journal: Blood
Blood (2020) 136 (6): 657–668.
https://doi.org/10.1182/blood.2020006075
Published: 2020
Includes: Supplemental data
Journal Articles

Type I Interferon Response Identified through Phenotypic and Transcriptional Profiling of Circulating Immune Cells during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Alberto Japp, PhD, Michael Gonzalez, PhD, Rozena Rasheed, BS, Sheila K Pierson, MS, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Frits van Rhee, MD PhD, Michael Betts, PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1046.
https://doi.org/10.1182/blood-2019-128994
Published: 2019
Journal Articles

Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Lam T. Khuat, PhD, Catherine T. Le, BS, Chien-Chun Pai, DVM, PhD, Robin Shields-Cutler, PhD, Shernan Holtan, MD, Armin Rashidi, MD PhD, Sarah Parker, MD, Dan Knights, PhD, Jesus I. Luna, PhD, Cordelia Dunai, MS, Ziming Wang, PhD, Ian R. Sturgill, MS, Kevin Stoffel, MS, Alexander A. Merleev, PhD, Emanual Maverakis, MD, Helen Raybould, PhD, Mingyi Chen, MD PhD, Robert J. Canter, MD, Arta M. Monjazeb, MD PhD, James L. M. Ferrara, MDDSc, John E. Levine, MDMS, Dan L. Longo, MD, Mehrdad Abedi, MD, Bruce R. Blazar, MD, William J. Murphy, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1922.
https://doi.org/10.1182/blood-2019-127743
Published: 2019
Journal Articles

PD-L1 Checkpoint Blockade Augments Anti-Tumor Immune Response of GD2 or HER2-Bsab Ex Vivo Armed T-Cells (EVAT) Therapy in Osteosarcoma

Jeong A Park, MD PhD, Hong fen Guo, PhD, Hong Xu, PhD, Nai-Kong V. Cheung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1959.
https://doi.org/10.1182/blood-2019-131325
Published: 2019
Journal Articles

Calming the storm in HLH

Matt S. Zinter, Michelle L. Hermiston
Journal: Blood
Blood (2019) 134 (2): 103–104.
https://doi.org/10.1182/blood.2019001333
Published: 2019
Journal Articles

The Innate Immune Sensor Sting Regulates Intestinal Inflammation and GVHD after Allogeneic Hematopoietic Stem Cell Transplantation in Knock-out and Human Allele Knock-in Recipient Mice

Cameron S. Bader, BS, Henry Barreras, MPH, Casey O. Lightbourn, MS, Sabrina Copsel, PhD, Jeonghyun Ahn, PhD, Glen N. Barber, PhD, Lei Jin, PhD MSc, Robert B. Levy, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 65.
https://doi.org/10.1182/blood-2018-99-109999
Published: 2018
Journal Articles

Serum Proteomics Reveals Distinct Subtypes Associated with Treatment Response in Idiopathic Multicentric Castleman Disease

Dustin Shilling, PhD, Jason R Ruth, PhD, Christopher Sheild Nabel, MD PhD, Sheila K Pierson, MS, Mary Guilfoyle, MS, Craig Tendler, MD, Manjula P Reddy, MS, MSc, Michael Weinblatt, MD, Nancy Shadick, MD MPH, Mark Bower, MD, Alessia Dalla Pria, MD, Yasufumi Masaki, MD PhD, Philip Beineke, MS, Sofija Miljovska, MS, Laura Katz, MA, Sushila Shenoy, PhD, Ana B Oromendia, PhD, Jason Mezey, PhD, Jeff Wiser, MS, Jef Benbanaste, MBA, David Lee, MA, Alexander Fosså, MD PhD, Frits van Rhee, MD PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3716.
https://doi.org/10.1182/blood-2018-99-119135
Published: 2018
Journal Articles

A Refined Regimen for Maximally Eliminating Early Life-Threatening Complications for Patients with High-Risk Acute Promyelocytic Leukemia

Sanbin Wang, Lihui Peng, Lin Liu, Le Luo, Stephen Liang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3994.
https://doi.org/10.1182/blood-2018-99-118620
Published: 2018
Journal Articles

Therapeutic Effect of Platelet Transfusion in Patients with Acute Lymphocytes Treated with CART Therapy

Liu Yan, MD, Xie Jue, MD PhD, Yongxian Hu, MD PhD, He Huang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5073.
https://doi.org/10.1182/blood-2018-99-120108
Published: 2018
Journal Articles

Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells Reveals Changes in Immune Cell Composition and Distinct Inflammatory Gene Expression Profiles during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Dustin Shilling, PhD, Michael Gonzalez, PhD, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2406.
https://doi.org/10.1182/blood-2018-99-110461
Published: 2018
Journal Articles

Oligoclonal Expansion of Cd8+ T Cells during Idiopathic Multicentric Castleman Disease Flares Suggests an Antigen Driven Process

Dustin Shilling, PhD, Jason E Stadanlick, PhD, Wenzhao Meng, PhD, Abhishek Rao, MS, Vera P Krymskaya, PhD MBA, FCPP, Eline T. Luning Prak, MD, PhD, Evgeniy B Eruslanov, PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2411.
https://doi.org/10.1182/blood-2018-99-118650
Published: 2018
Journal Articles

Pi3k/Akt/Mtor Pathway Activity Is Increased in Lymph Node Tissue from Idiopathic Multicentric Castleman Disease Patients with Tafro Syndrome

Dustin Shilling, PhD, Dale M Kobrin, BA, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 1121.
https://doi.org/10.1182/blood-2018-99-118434
Published: 2018
Journal Articles

Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease

David C. Fajgenbaum
Journal: Blood
Blood (2018) 132 (22): 2323–2330.
https://doi.org/10.1182/blood-2018-05-848671
Published: 2018
Journal Articles

Modulation of Donor Graft By the Steroidal Lactone Withaferin A Alleviates Post-Transplant Acute GVHD Via Nrf-2 Independent T-Reg Induction

Vikram Gota, MD, Miten Mehta, PhD, Dievya Gohil, MSc, Dhruv Jha, M.Pharm, Rajiv Kumar, MBBS, MD DM, Beamon Agarwal, MD PhD, Deepak Sharma, PhD, Santosh Sandur, PhD, Navin Khattry, MD DM, Anuradha Majumdar, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3174.
https://doi.org/10.1182/blood.V130.Suppl_1.3174.3174
Published: 2017
Journal Articles

Pharmacological Control of Recipient NK Cell Function By Venetoclax Promotes Engraftment and Limits GVHD Following Reduced Intensity Conditioning without Impacting the Graft Versus AML Effect

Joanne Davis, PhD, Yuhao Jiao, Nicholas Huntington, PhD, David Ritchie, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3177.
https://doi.org/10.1182/blood.V130.Suppl_1.3177.3177
Published: 2017
Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Yoshihiro Hayashi, MD PhD, Rui Huang, MD PhD, Xiaomei Yan, Jiachen BU, PhD, Jieyu Wang, MD PhD, Yue Zhang, MD PhD, Yile Zhou, MD, Yuting Tang, MD, Lingyun Wu, MD PhD, Zefeng Xu, MD, Xin Liu, MD PhD, Qianfei Wang, PhD, Jianfeng Zhou, Zhijian Xiao, James P Bridges, PhD, Rebecca A Marsh, Kejian Zhang, MD MBA, Michael B. Jordan, MD, Yuhua Li, MD, Gang Huang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3565.
https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565
Published: 2017
Journal Articles

Beyond Cytokine Storm: Optimizing Treatment Strategies to Target the Complex Interplay between CAR Mediated Inflammatory Response, Disseminated Intravascular Coagulation and Macrophage Activation Syndrome

Nirali N Shah, MD, Haneen Shalabi, DO, Bonnie Yates, RN, Eli Kane, Alina Dulau-Florea, MD, Anne Cullinane, BS, Cynthia Delbrook, RN, Michael Ombrello, MD, Amanda Ombrello, MD, Jay Nelson Lozier, MD PhD, Terry J. Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1277.
https://doi.org/10.1182/blood.V130.Suppl_1.1277.1277
Published: 2017