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Journal Articles

The Biological Inferences from the Ranking of SF3B1 Mutations in the Clonal Hierarchy of Myeloid Neoplasia

Hassan Awada, Jibran Durrani, Ashwin Kishtagari, MBBS, Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Bartlomiej Przychodzen, Jack Khouri, MD, Heesun J. Rogers, MD PhD, Manja Meggendorfer, PhD, Anjali S. Advani, MD, Aziz Nazha, MD, Torsten Haferlach, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 5411.

https://doi.org/10.1182/blood-2019-128965

Published: 2019

Journal Articles

Endogenous Retinoid X Receptor Ligands Act As Tumor Suppressors in MLL-AF9 Mouse Leukemia

Orsola Di Martino, PhD, Margaret Y Ferris, MD PhD, Hadwiger Gayla, Haixia Niu, PhD, John S. Welch, MD PhD

Blood (2019) 134 (Supplement_1): 2677.

https://doi.org/10.1182/blood-2019-128869

Published: 2019

Journal Articles

The LSD1 Inhibitor RN-1 Increases γ-Globin Expression in Baboons By Targeting an Early Event Responsible for γ-Globin Repression

Kestis Vaitkus, Vinzon Ibanez, B.S., Maria Armila Ruiz, B.S., Ramasamy Jagadeeswaran, PhD, Yogenthiran Saunthararajah, MD, James Douglas Engel, PhD, Joseph DeSimone, PhD, Angela Rivers, MD, Donald Lavelle, PhD

Blood (2018) 132 (Supplement 1): 1054.

https://doi.org/10.1182/blood-2018-99-113539

Published: 2018

Journal Articles

KLF1 Acts As a Pioneer Transcription Factor to Open Chromatin and Facilitate Recruitment of GATA1

Kevin R. Gillinder, PhD, Graham Magor, BSc, Charles Bell, BSc, Melissa D. Ilsley, BSc PhD, Stephen Huang, BSc, Andrew Perkins, MBBS, PhD, FRCPA, FRACP

Blood (2018) 132 (Supplement 1): 501.

https://doi.org/10.1182/blood-2018-99-119608

Published: 2018

Journal Articles

A First-in-Class Inhibitor of ISWI-Mediated (ATP-Dependent) Transcription Repression Releases Terminal-Differentiation in AML Cells While Sparing Normal Hematopoiesis

Ashwin Kishtagari, MBBS, Kwok Peng Ng, PhD, Charlotte Jarman, Anand D. Tiwari, PhD, James G Phillips, PhD, Caroline Schuerger, Babal K. Jha, Yogenthiran Saunthararajah, MD

Blood (2018) 132 (Supplement 1): 216.

https://doi.org/10.1182/blood-2018-99-119311

Published: 2018

Journal Articles

The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy

Xiaorong Gu, PhD, Quteba Ebrahem, MD, Reda Z. Mahfouz, MD PhD, Metis Hasipek, PhD, Francis Enane, PhD, Tomas Radivoyevitch, Nicolas Rapin, PhDMSc, Bartlomiej P. Przychodzen, MSc, Ramesh Balusu, PhD, Claudiu V Cotta, David Wald, MD PhD, Zhenbo Hu, MD PhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Babal K Jha, PhD, Yogenthiran Saunthararajah, MD

Blood (2017) 130 (Supplement 1): 878.

https://doi.org/10.1182/blood.V130.Suppl_1.878.878

Published: 2017

Journal Articles

Inhibiting Aurora Kinase B Sensitizes B-Cell Acute Lymphoblastic Leukemia to Glucocorticoids

Coralie Poulard, Hye Na Kim, Celine Gagnieux, Karina Kruth, PhD, Mimi Fang, Daniel Gerke, Deepa Bhojwani, MD, Yong-Mi Kim, MD MPH, PhD, Michael R Stallcup, PhD, Miles A. Pufall, PhD

Blood (2017) 130 (Supplement 1): 5113.

https://doi.org/10.1182/blood.V130.Suppl_1.5113.5113

Published: 2017

Journal Articles

MTG16 Variants Provide Context to Notch Signaling to Direct Leukemic Phenotype

Helena Lucente, BS, Diana Bareyan, MS, David McClellan, BS, Mattie Casey, BA, Michael Engel, MD PhD

Blood (2017) 130 (Supplement 1): 3746.

https://doi.org/10.1182/blood.V130.Suppl_1.3746.3746

Published: 2017

Journal Articles

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Lynsey McKenzie, PhD, Natalia Martinez-Soria, PhD, Julia Draper, DPhil, Sirintra Nakjang, PhD, Helen J Blair, PhD, Christian Wichmann, MD, Josef Vormoor, MD FRCPCH, Constanze Bonifer, PhD, Georges Lacaud, PhD, Olaf Heidenreich, PhD

Blood (2016) 128 (22): 835.

https://doi.org/10.1182/blood.V128.22.835.835

Published: 2016

Journal Articles

In Silico and Functional Characterization of TBL1XR1 as a Tumor Suppressor in Large B-Cell Lymphomas

Bjoern Chapuy, MD PhD, Atanas Kamburov, PhD, Caroline A Coughlin, Chip Stewart, PhD, Andrew Dunford, Miyuki Aono, Jens Loeber, Christopher Sauer, Arthur Su, Margaretha G M Roemer, Scott J Rodig, Gad Getz, PhD, Margaret A. Shipp, MD

Blood (2016) 128 (22): 612.

https://doi.org/10.1182/blood.V128.22.612.612

Published: 2016

Journal Articles

Protein Arginine Methyltransferase 5 Regulates WNT/β-Catenin Target Gene Expression in at Multiple Levels

Jihyun Chung, PhD, Vrajesh Karkhanis, PhD, Sif Said, PhD, Robert A Baiocchi, MD PhD

Blood (2016) 128 (22): 4106.

https://doi.org/10.1182/blood.V128.22.4106.4106

Published: 2016

Journal Articles

Driver Mutations Affecting Natural Killer/T Cell Lymphoma

Gehong DONG, PhD, Qiang Gong, PhD, Jinhui Wang, Xiwei Wu, PhD, Yuping Li, PhD, Leticia Quintanilla-Martinez Fend, Prof. Dr., Jingwen Wang, MD, Hong-gang Liu, Timothy W. McKeithan, MD PhD, Wing Chung Chan, MD

Blood (2016) 128 (22): 4109.

https://doi.org/10.1182/blood.V128.22.4109.4109

Published: 2016

Journal Articles

Role of Histone Deacetylase-Mediated Gene Silencing in Chronic Lymphocytic Leukemia Progression

Lara Rizzotto, PhD, Arianna Bottoni, PhD, Tzung-Huei Lai, PhD, Chaomei Liu, BS, Pearlly S Yan, PhD, Hatice G Ozer, PhD, Rosa Lapalombella, PhD, Jennifer A. Woyach, MD, Christopher C Oakes, PhD, James S. Blachly, MD, Deepa Sampath, PhD

Blood (2016) 128 (22): 2705.

https://doi.org/10.1182/blood.V128.22.2705.2705

Published: 2016

Journal Articles

p62-ZZ Domain Signaling Inhibition Rescues MM-Induced Epigenetic Repression at the Runx2 promoter and Allows Osteoblast Differentiation of MM Patient Pre-Osteoblasts In Vitro

Rebecca Silbermann, MD, Juraj Adamik, PhD, Dan Zhou, Xiang-Qun Xie, MD PhD EMBA, Noriyoshi Kurihara, DDS, PhD, G. David Roodman, MD PhD, Deborah Lynn Galson, PhD

Blood (2016) 128 (22): 4410.

https://doi.org/10.1182/blood.V128.22.4410.4410

Published: 2016

Journal Articles

Optimizing therapy for nodal marginal zone lymphoma

Catherine Thieblemont, Thierry Molina, Frédéric Davi

Blood (2016) 127 (17): 2064–2071.

https://doi.org/10.1182/blood-2015-12-624296

Published: 2016

Journal Articles

LIM-Domain Protein Ajuba Is a Required Co-Factor for Gfi1-Induced Epigenetic Switch Regulating Runx2 Repression in Multiple Myeloma-Exposed Pre-Osteoblasts

Juraj Adamik, PhD, Jixin Ding, PhD, Wei Zhao, Peng Zhang, PhD, Quanhong Sun, G. David Roodman, MD PhD, Deborah Lynn Galson, PhD

Blood (2015) 126 (23): 4216.

https://doi.org/10.1182/blood.V126.23.4216.4216

Published: 2015

Journal Articles

Identification of BCL6 As a Therapeutic Target in RAS -Driven Acute Lymphoblastic Leukemia

Qiang Li, PhD, Christian Hurtz, PhD, Seyedmehdi Shojaee, PhD, Zhengshan Chen, MDPhD, Huimin Geng, PhD, Gang Xiao, PhD, Mignon L. Loh, MD, B. Hilda Ye, PhD, Ari Melnick, MD, Markus Muschen, MDPhD

Blood (2015) 126 (23): 556.

https://doi.org/10.1182/blood.V126.23.556.556

Published: 2015

Journal Articles

Loss of the TLE4 AML Tumor Suppressor Gene Contributes to Leukemic Cell Proliferation, Differentiation Arrest, and Chemotherapy Resistance through a COX-Dependent Inflammatory Pathway

Thomas H Shin, David A Sweetser, MD,PhD

Blood (2015) 126 (23): 1241.

https://doi.org/10.1182/blood.V126.23.1241.1241

Published: 2015

Journal Articles

Transcriptional Control of HSC Fitness

David E. Muench, MEng, Chinavenmeni S. Velu, PhD, Andre Olsson, PhD, Sara E. Meyer, PhD, H. Leighton Grimes, PhD

Blood (2015) 126 (23): 1161.

https://doi.org/10.1182/blood.V126.23.1161.1161

Published: 2015

Journal Articles

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

Tzung-Huei Lai, PhD, Alma Zecevic, Brett Ewald, PhD, Liu Chaomei, Lara Rizzotto, PhD, Melanie Sulda, Dimitrios Papaioannou, MD, Ramiro Garzon, MD, William Plunkett, PhD, Deepa Sampath, PhD

Blood (2015) 126 (23): 3639.

https://doi.org/10.1182/blood.V126.23.3639.3639

Published: 2015

NARROW

The Biological Inferences from the Ranking of SF3B1 Mutations in the Clonal Hierarchy of Myeloid Neoplasia

Endogenous Retinoid X Receptor Ligands Act As Tumor Suppressors in MLL-AF9 Mouse Leukemia

The LSD1 Inhibitor RN-1 Increases γ-Globin Expression in Baboons By Targeting an Early Event Responsible for γ-Globin Repression

KLF1 Acts As a Pioneer Transcription Factor to Open Chromatin and Facilitate Recruitment of GATA1

A First-in-Class Inhibitor of ISWI-Mediated (ATP-Dependent) Transcription Repression Releases Terminal-Differentiation in AML Cells While Sparing Normal Hematopoiesis

The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy

Inhibiting Aurora Kinase B Sensitizes B-Cell Acute Lymphoblastic Leukemia to Glucocorticoids

MTG16 Variants Provide Context to Notch Signaling to Direct Leukemic Phenotype

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

In Silico and Functional Characterization of TBL1XR1 as a Tumor Suppressor in Large B-Cell Lymphomas

Protein Arginine Methyltransferase 5 Regulates WNT/β-Catenin Target Gene Expression in at Multiple Levels

Driver Mutations Affecting Natural Killer/T Cell Lymphoma

Role of Histone Deacetylase-Mediated Gene Silencing in Chronic Lymphocytic Leukemia Progression

p62-ZZ Domain Signaling Inhibition Rescues MM-Induced Epigenetic Repression at the Runx2 promoter and Allows Osteoblast Differentiation of MM Patient Pre-Osteoblasts In Vitro

Optimizing therapy for nodal marginal zone lymphoma

LIM-Domain Protein Ajuba Is a Required Co-Factor for Gfi1-Induced Epigenetic Switch Regulating Runx2 Repression in Multiple Myeloma-Exposed Pre-Osteoblasts

Identification of BCL6 As a Therapeutic Target in RAS -Driven Acute Lymphoblastic Leukemia

Loss of the TLE4 AML Tumor Suppressor Gene Contributes to Leukemic Cell Proliferation, Differentiation Arrest, and Chemotherapy Resistance through a COX-Dependent Inflammatory Pathway

Transcriptional Control of HSC Fitness

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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