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Triple Negative (J AK2 exon 12 /14 and MPL wild type) Myelofibrosis Have Higher Expression Of CDC25A and Greater Sensitivity To CDC25A Inhibition Compared To JAK2 Mutant Cases

Ali Tabarroki, MD, Valeria Visconte, PhD, Heesun J. Rogers, MD, PhD, Juraj Bodo, PhD, Li Zhang, Felicitas Lacbawan, Edy Hasrouni, John Barnard, Alan E. Lichtin, Daniel Lindner, Mikkael A. Sekeres, MD, MS, Ramon V. Tiu, MD
Journal: Blood
Blood (2013) 122 (21): 5259.
https://doi.org/10.1182/blood.V122.21.5259.5259
Published: 2013
Journal Articles

The Small Molecule CHK1/CHK2 Inhibitor PF-0477736 (Pfizer) Demonstrates Single Agent Activity and Synergizes with Chemotherapy in Diffuse Large B-Cell Lymphoma

Enrico Derenzini, MD, Ilaria Iacobucci, PhD, Elisa Brighenti, PhD, Federica Cattina, MD, Richard Eric Davis, MD, Stefano Pileri, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Pier Luigi Zinzani, MD
Journal: Blood
Blood (2011) 118 (21): 2732.
https://doi.org/10.1182/blood.V118.21.2732.2732
Published: 2011
Journal Articles

Human Tissue Transglutaminase Activity Is Inhibited by Protein Kinase Inhibitors: Potential Therapeutic Implication for Hematological Disorders.

Thung-S. Lai, PhD, Yusha Liu, Ho Young Lee, Eric Toone, Ph.D., Charles S. Greenberg, M.D.
Journal: Blood
Blood (2006) 108 (11): 1614.
https://doi.org/10.1182/blood.V108.11.1614.1614
Published: 2006
Journal Articles

Increased Expression of Genes for Protooncoproteins SnoN and SnoA in Human Myeloblastic Leukemia ML2 Cells and Resistance of ML2 Cells to Transforming Growth Factor-beta-Induced Growth Arrest.

Ota Fuchs, Gabriela Peslova, Dana Provaznikova, Iuri Marinov
Journal: Blood
Blood (2005) 106 (11): 4347.
https://doi.org/10.1182/blood.V106.11.4347.4347
Published: 2005