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Journal Articles

Preanalytic depletion of medicinal anti-CD38 antibody from patient plasma for immunohematology testing

Elisabeth Ehrend, Patricia Manns, Sabine Harenkamp, Erhard Seifried, Christof Geisen, Halvard Bonig
Journal: Blood
Blood (2021) 138 (9): 814–817.
https://doi.org/10.1182/blood.2021011396
Published: 2021
Includes: Supplemental data
Journal Articles

T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis

Vandana Chaturvedi, Rebecca A. Marsh, Adi Zoref-Lorenz, Erika Owsley, Vijaya Chaturvedi, Trung C. Nguyen, Jordana R. Goldman, Michael M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Michael Jeng, Ahmed Naqvi, Carl E. Allen, Hector R. Wong, Michael B. Jordan
Journal: Blood
Blood (2021) 137 (17): 2337–2346.
https://doi.org/10.1182/blood.2020009499
Published: 2021
Includes: Supplemental data
Journal Articles

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Elisa Ten Hacken, PhD, Shanye Yin, PhD, Kendell Clement, PhD, Robert A. Redd, MS, Maria Hernandez-Sanchez, PhD, Shuqiang Li, PhD, Michaela Gruber, MD PhD, Heather Joyal, Geoffrey Fell, MS, Shu Wang, Jose Jacob, James Flynn, David Ruff, Keith W. Jones, Lili Wang, MD PhD, Donna S Neuberg, ScD, Luca Pinello, PhD, Kenneth J. Livak, PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 684.
https://doi.org/10.1182/blood-2019-127673
Published: 2019
Journal Articles

FT538: Preclinical Development of an Off-the-Shelf Adoptive NK Cell Immunotherapy with Targeted Disruption of CD38 to Prevent Anti-CD38 Antibody-Mediated Fratricide and Enhance ADCC in Multiple Myeloma When Combined with Daratumumab

Ryan Bjordahl, PhD, Svetlana Gaidarova, MS, Karrune Woan, MD PhD, Frank Cichocki, PhD, Greg Bonello, PhD, Megan Robinson, Chelsea Ruller, Mochtar Pribadi, PhD, Jason Dinella, PhD, Lauren Fong, PhD, Janel Huffman, MS, Hui-yi Chu, PhD, Tom Lee, PhD, Ramzey Abujarour, PhD, Dan S Kaufman, MD PhD, Karl-Johan Malmberg, MD PhD, Jeffrey S. Miller, MD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 133.
https://doi.org/10.1182/blood-2019-131138
Published: 2019
Journal Articles

The Prognostic Impact of the Diagnostic CD34+/CD38- Cell Burden and Expression of the Stem Cell Marker GPR56 after Stem Cell Transplantation Depends on the AML Origin

Madlen Jentzsch, MD, Marius Bill, MD PhD, Juliane Grimm, MD, Dominic Brauer, MD, Julia Schulz, Karoline Goldmann, Dietger Niederwieser, MD, Uwe Platzbecker, Sebastian Schwind, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 323.
https://doi.org/10.1182/blood-2019-127544
Published: 2019
Journal Articles

Preliminary Results from a Phase 1b Study of TAK-079, an Investigational Anti-CD38 Monoclonal Antibody (mAb) in Patients with Relapsed/ Refractory Multiple Myeloma (RRMM)

Amrita Y. Krishnan, MD, Krina K. Patel, MD MSc, Parameswaran Hari, MBBS, MD, Sundar Jagannath, MD, Ruben Niesvizky, MD, Rebecca W. Silbermann, MD, Deborah Berg, RN, MSN, Jianchang Lin, PhD, Eric Robert Fedyk, BSc, MSc, PhD, Antonio Palumbo, MD, Keith E. Stockerl-Goldstein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 140.
https://doi.org/10.1182/blood-2019-128007
Published: 2019
Journal Articles

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Acute Leukemia in Children

Larisa Shelikhova, MD, Rimma Khismatullina, MD, Michael Maschan, MD MSc, Alexey A. Maschan, MD, Irina Kalinina, MD, Elena Kurnikova, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Alexander Popov, MD PhD, Galina Novichkova, MD PhD, Dmitriy Balashov, MD PhD, Daria Shasheleva, MD, Svetlana Kashpor, Evgeny Gluhanyuk
Journal: Blood
Blood (2019) 134 (Supplement_1): 150.
https://doi.org/10.1182/blood-2019-129765
Published: 2019
Journal Articles

Superior Efficacy of CAR-T Cells Using Marrow-Infiltrating Lymphocytes (MILs TM ) As Compared to Peripheral Blood Lymphocytes (PBLs)

Eric R. Lutz, PhD, Srikanta Jana, PhD, Lakshmi Rudraraju, MS, Elizabeth DeOliveira, Jing Zhou, Sean Mackay, Ivan M. Borrello, MD, Kimberly Noonan, PhD MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4437.
https://doi.org/10.1182/blood-2019-130629
Published: 2019
Journal Articles

A Novel Class of Bifunctional Immunotherapeutic That Exploit a Universal Antibody Binding Terminus (uABT) to Recruit Endogenous Antibodies to Cells Expressing CD38 Demonstrates Anti-Multiple Myeloma Activity in Vitro and Ex Vivo against Patient Tumor Cells

Ann Marie Rossi, MS, Anna Bunin, PhD, Lawrence Iben, BS, MA, Matthew Welsch, PhD, Tanya Berbasova, PhD, Caterina Riillo, Marco Rossi, Masaki Ohuchi, PhD, Enrique Alvarez, DVM, Naoko Kawakami, Takayuki Nagasawa, PhD, Pierfrancesco Tassone, MD, David Spiegel, MD, PhD, Luca Rastelli, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4411.
https://doi.org/10.1182/blood-2019-131794
Published: 2019
Journal Articles

Development of a Genetically-Engineered Allogeneic Anti-CD38 T Cell Therapy Utilizing a Novel Antigen Receptor Structure

Bei Bei Ding, PhD, John Dixon Gray, PhD, Irina Krapf, MSc, Yanliang Zhang, PhD, Nan Zhang, Qingdong Mark Deng, Angel Wei, MD, Robert D. Knight, MD, Jerome B. Zeldis, MD PhD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Wenzhong Guo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4444.
https://doi.org/10.1182/blood-2019-131586
Published: 2019
Journal Articles

The Locommotion Study (MMY4001): A Prospective, Multinational Study of Real-Life Current Standards of Care in Patients with Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including PI, IMiD, and CD38 Monoclonal Antibody Treatment and Documented Disease Progression

Michel Delforge, MD PhD, Philippe Moreau, MD, Maria-Victoria Mateos, Valerio De Stefano, MD, Katja Weisel, Jesús San-Miguel, Hermann Einsele, MD, Thierry Facon, MD, Mario Boccadoro, Hartmut Goldschmidt, Michele Cavo, Laura Rosinol, MD PhD, Martin F. Kaiser, Francesca Gay, MD, Christof Scheid, MD, Annemiek Broyl, MD PhD, Niels W. C. J. Van De Donk, MD PhD, Paula Rodriguez, MD, Anna Potamianou, Caline Sakabedoyan, Vadim Strulev, Tonia Nesheiwat, Paul Bergmans, Syed Rizvi, MD, Arkadiusz Pilatowicz, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 5549.
https://doi.org/10.1182/blood-2019-122939
Published: 2019
Journal Articles

Preclinical Development of an Anti-CD38 Antibody-Drug Conjugate for Treatment of Hematological Malignancies

Lingna Li, PhD, Wenyong Tong, PhD, Megan Lau, BS, Katherine Fells, PhD, Tong Zhu, PhD, Yingqing Sun, PhD, Ernest Kovacs, PhD, Alisher Khasanov, PhD, Zheng Yan, PhD, Dalun Deng, PhD, Ken Takeshita, MD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Hui Li, PhD, Hong Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5621.
https://doi.org/10.1182/blood-2019-132062
Published: 2019
Journal Articles

Novel Lymphoid Pathway of Human Plasmacytoid and Conventional Dendritic Cells

Keiki Nagaharu, MD, Kohshi Ohishi, MD PhD, Naoyuki Katayama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4998.
https://doi.org/10.1182/blood-2019-121448
Published: 2019
Journal Articles

Features of an Unusual AML with t(4;12)/ Pdgra-ETV6 As the Sole Cytogenetic Abnormality Associated with Myelodysplastic Changes: A Case Report and Literature Review

Jitakshi De, MD, L. Jeffrey Medeiros, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5162.
https://doi.org/10.1182/blood-2019-129035
Published: 2019
Journal Articles

Mitochondrial Oxphos As Survival Mechanism of Minimal Residual AML Cells after Induction Chemotherapy : Survival Benefit By Complex I Inhibition with Iacs-010759

Lina Han, PhD, Antonio Cavazos, Natalia Baran, PhDMD, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Jason P Gay, MS, Ningping Feng, PhD, Venkata Lokesh Battula, PhD, Hagop M. Kantarjian, MD, Naval G. Daver, MD, Joseph R Marszalek, PhD, Michael Andreeff, MD PhD, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5161.
https://doi.org/10.1182/blood-2019-124475
Published: 2019
Journal Articles

Predicting the Long-Term Efficacy of Ifnα in JAK2 V617F and Calr -Mutated MPN Patients

Amandine Tisserand, Robert Noble, PhD, Matthieu Mosca, PhD, Christophe Marzac, MD, Gaelle Vertenoeil, MD, Hugo Campario, PharmD, Mira El-Khoury, PhD, Caroline Marty, PhD, Philippe Rameau, Nicole Casadevall, MD, Eric Solary, MD PhD, Florence Pasquier, MD PhD, Hana Raslova, PhD, Bruno Cassinat, PharmD, PhD, Stefan N Constantinescu, MD PhD, Jean-Jacques Kiladjian, MD PhD, Francois Girodon, MD PhD, Michael Hochberg, PhD, Villeval Jean-Luc, PhD, William Vainchenker, MD PhD, Isabelle Plo
Journal: Blood
Blood (2019) 134 (Supplement_1): 4196.
https://doi.org/10.1182/blood-2019-127903
Published: 2019
Journal Articles

FT576: A Novel Multiplexed Engineered Off-the-Shelf Natural Killer Cell Immunotherapy for the Dual-Targeting of CD38 and Bcma for the Treatment of Multiple Myeloma

Ryan Bjordahl, PhD, Svetlana Gaidarova, MS, Jode P Goodridge, PhD, Sajid Mahmood, PhD, Greg Bonello, PhD, Megan Robinson, Chelsea Ruller, Mochtar Pribadi, PhD, Tom Lee, PhD, Ramzey Abujarour, PhD, Jason Dinella, PhD, Janel Huffman, MS, Hui-yi Chu, PhD, Uta Hopken, Armin Rehm, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3214.
https://doi.org/10.1182/blood-2019-131373
Published: 2019
Journal Articles

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death

Frank Cichocki, PhD, Karrune Woan, MD PhD, Cheng-Ying Wu, Bruce R. Blazar, MD, Ryan Bjordahl, PhD, Bahram Valamehr, PhD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3215.
https://doi.org/10.1182/blood-2019-124490
Published: 2019
Journal Articles

Long-Term Outcome of Total Therapy Regimens: Impact of Molecular Subgroups

Frits van Rhee, MD PhD, Maurizio Zangari, MD, Carolina D. Schinke, MD, Guido J. Tricot, MD PhD, Doug Steward, Susan Panozzo, Jeffery R. Sawyer, Brian A Walker, PhD, Joshua Epstein, DSc, Faith E. Davies, MD, Gareth Morgan, MD PhD, Adam Rosenthal, MS, Antje Hoering, PhD, Katherine K Nishimura, Bart Barlogie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3309.
https://doi.org/10.1182/blood-2019-131870
Published: 2019
Journal Articles

Inter-Cell Networking Profiling Enables Comprehensive Characterization of Immune-Mediated Activity of Anti-CD38 Therapy through Ex-Vivo Analysis of Multiple Myeloma Patients

Alice Bettelli, MS, Rita Ruggiano, Silvia Bocchi, Laura Rocchi, PhD, Andrea Faenza, PhD, Enrica Borsi, Carolina Terragna, Elena Zamagni, MD, Marina Martello, Marco Bettelli, Laura Rambelli, Viviana Guadagnuolo, Nicola Pecorari, Luca Giulianelli, Matteo Pisani, Dario Biscarini, Michele Cavo, Roberto Guerrieri, Massimo Bocchi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3372.
https://doi.org/10.1182/blood-2019-126894
Published: 2019