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Journal Articles

FT538: Preclinical Development of an Off-the-Shelf Adoptive NK Cell Immunotherapy with Targeted Disruption of CD38 to Prevent Anti-CD38 Antibody-Mediated Fratricide and Enhance ADCC in Multiple Myeloma When Combined with Daratumumab

Ryan Bjordahl, PhD, Svetlana Gaidarova, MS, Karrune Woan, MD PhD, Frank Cichocki, PhD, Greg Bonello, PhD, Megan Robinson, Chelsea Ruller, Mochtar Pribadi, PhD, Jason Dinella, PhD, Lauren Fong, PhD, Janel Huffman, MS, Hui-yi Chu, PhD, Tom Lee, PhD, Ramzey Abujarour, PhD, Dan S Kaufman, MD PhD, Karl-Johan Malmberg, MD PhD, Jeffrey S. Miller, MD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 133.
https://doi.org/10.1182/blood-2019-131138
Published: 2019
Journal Articles

FT576: A Novel Multiplexed Engineered Off-the-Shelf Natural Killer Cell Immunotherapy for the Dual-Targeting of CD38 and Bcma for the Treatment of Multiple Myeloma

Ryan Bjordahl, PhD, Svetlana Gaidarova, MS, Jode P Goodridge, PhD, Sajid Mahmood, PhD, Greg Bonello, PhD, Megan Robinson, Chelsea Ruller, Mochtar Pribadi, PhD, Tom Lee, PhD, Ramzey Abujarour, PhD, Jason Dinella, PhD, Janel Huffman, MS, Hui-yi Chu, PhD, Uta Hopken, Armin Rehm, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3214.
https://doi.org/10.1182/blood-2019-131373
Published: 2019
Journal Articles

Multi-Functional Genetic Engineering of Pluripotent Cell Lines for Universal Off-the-Shelf Natural Killer Cell Cancer Immunotherapy

Ryan Bjordahl, PhD, Raedun Clarke, PhD, Svetlana Gaidarova, Matthieu Bauer, PhD, Jeff Sasaki, Brian Groff, Tom Lee, PhD, Weijie Lan, PhD, Ramzey Abujarour, PhD, Greg Bonello, PhD, Megan Robinson, Ian Hardy, PhD, Daniel Shoemaker, PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3187.
https://doi.org/10.1182/blood.V130.Suppl_1.3187.3187
Published: 2017
Journal Articles

Clinical Translation of Pluripotent Cell-Derived Off-the-Shelf Natural Killer Cell Cancer Immunotherapy

Frank Cichocki, Ryan Bjordahl, PhD, Svetlana Gaidarova, Paul Rogers, Raedun Clarke, PhD, Brian Groff, Stacey Moreno, Ramzey Abujarour, PhD, Megan Robinson, Greg Bonello, PhD, Tom Lee, PhD, Weijie Lan, PhD, Betsy Rezner, BS, Stewart Abbot, Darin Sumstad, MLS, Bruce Blazar, MD, Daniel Shoemaker, PhD, Scott Wolchko, Dan Kaufman, MD, David H. McKenna, MD, Bahram Valamehr, PhD, Sarah Cooley, MD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 656.
https://doi.org/10.1182/blood.V130.Suppl_1.656.656
Published: 2017
Journal Articles

Off-the-Shelf Natural Killer Cell Immunotherapy for Enhanced Antibody Directed Cellular Cytotoxicity

Ryan Bjordahl, PhD, Raedun Clarke, PhD, Svetlana Gaidarova, M.S., Brian Groff, B.S., Paul Rogers, PhD, Stacey Moreno, Ramzey Abujarour, PhD, Greg Bonello, PhD, Tom Tong Lee, PhD, Weijie Lan, PhD, Michelle Burrascano, Matthieu Bauer, PhD, Megan Robinson, BS, Jeff Sasaki, William Kim, PhD, David Robbins, BS, Betsy Rezner, BS, Stewart E. Abbot, PhD BSc, MSc, Scott Wolchko, MS, Daniel Shoemaker, PhD, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 3363.
https://doi.org/10.1182/blood.V128.22.3363.3363
Published: 2016
Journal Articles

Genetically Enhanced Pluripotent Stem Cell-Derived T Lymphocytes for Off-the-Shelf Cellular Immunotherapy

Raedun Clarke, PhD, Brian Groff, B.S., Jeffrey Sasaki, B.S., Matthieu Bauer, PhD, Tom Tong Lee, PhD, Weijie Lan, PhD, Michelle Burrascano, Ramzey Abujarour, PhD, Greg Bonello, Megan Robinson, BS, Heather Foster, David Robbins, BS, Scott Wolchko, MS, Daniel Shoemaker, PhD, Stewart E. Abbot, PhD BSc, MSc, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 2164.
https://doi.org/10.1182/blood.V128.22.2164.2164
Published: 2016
Journal Articles

Genetic Engineering of Pluripotent Cells for the Continuous Derivation of Off-the-Shelf Effector Lymphocytes with Enhanced Therapeutic Persistence By Overcoming the Host Histocompatibility Barrier

Matthieu Bauer, PhD, Raedun Clarke, PhD, Jeffrey Sasaki, B.S., Brian Groff, B.S., Tom Tong Lee, PhD, Weijie Lan, PhD, Ramzey Abujarour, PhD, Greg Bonello, Michelle Burrascano, Megan Robinson, BS, Ryan Bjordahl, PhD, Svetlana Gaidarova, M.S., Stewart E. Abbot, PhD BSc, MSc, Scott Wolchko, MS, Daniel Shoemaker, PhD, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 2165.
https://doi.org/10.1182/blood.V128.22.2165.2165
Published: 2016
Journal Articles

Efficient Site-Specific Multi-Gene Engineering of Renewable Pluripotent Cells for Generation of Off-the-Shelf Hematopoietic Immunotherapeutics

Ramzey Abujarour, PhD, Weijie Lan, PhD, Tom Tong Lee, PhD, Greg Bonello, Miguel Meza, MS, Megan Robinson, BS, Raedun Clarke, PhD, Christopher Truong, Chris Lynn, BS, David Robbins, BS, Betsy Rezner, BS, Stewart E. Abbot, PhD BSc, MSc, Daniel Shoemaker, PhD, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 5887.
https://doi.org/10.1182/blood.V128.22.5887.5887
Published: 2016
Journal Articles

A Platform for the Scalable Derivation of Genetically-Enhanced T and NK Lymphocytes from Naive Human Induced Pluripotent Stem Cells for Cancer Immunotherapy

Raedun Clarke, PhD, William Kim, PhD, Brian Groff, BS, Ramzey Abujarour, PhD, Megan Robinson, BS, Xiaosong Huang, PhD, Newsha Sahaf, Sarah Raynel, MS, Betsy Rezner, BS, David Robbins, BS, Lisa Guerrettaz, PhD, Daniel Shoemaker, PhD, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2015) 126 (23): 2364.
https://doi.org/10.1182/blood.V126.23.2364.2364
Published: 2015
Journal Articles

Human Induced Pluripotent Stem Cells Incorporating Safe Harbor Loci Integrated Inducible Suicide Systems for Use in the Application of Cellular Therapeutics

Xiaosong Huang, PhD, Weijie Lan, PhD, Philippe Parone, PhD, Raedun Clarke, PhD, Ramzey Abujarour, PhD, Megan Robinson, BS, Miguel Meza, MS, Sarah Raynel, MS, Betsy Rezner, BS, David Robbins, BS, Tom Tong Lee, PhD, Daniel Shoemaker, PhD, Bahram Valamehr, PhD MBA
Journal: Blood
Blood (2015) 126 (23): 3237.
https://doi.org/10.1182/blood.V126.23.3237.3237
Published: 2015