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Journal Articles

Identification of a Novel CEBPE Enhancer Essential for Granulocytic Differentiation

Pavithra Shyamsunder, PhD, Mahalakshmi Shanmugasundaram, Anand Mayakonda, Weoi Woon Teoh, Lin Han, MSc, Mei Chee Lim, Melissa Fullwood, Omer An, Henry Yang, PhD, Shi Jizhong, Md.Zakhir Hossain, Vikas Madan, PhD, H. Phillip Koeffler, MD

Blood (2018) 132 (Supplement 1): 3834.

https://doi.org/10.1182/blood-2018-99-116091

Published: 2018

Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 3721.

https://doi.org/10.1182/blood-2018-99-119389

Published: 2018

Journal Articles

Optimizing Mechanisms for Induction of Immunogenic Cell Death to Improve Patient Outcome in Multiple Myeloma

Annamaria Gulla, MD, Eugenio Morelli, MD, Teru Hideshima, MD PhD, Mehmet Kemal Samur, PhD, Giada Bianchi, MD, Mariateresa Fulciniti, PhD, Nikhil Munshi, MD, Kenneth C. Anderson, MD

Blood (2018) 132 (Supplement 1): 1932.

https://doi.org/10.1182/blood-2018-99-116951

Published: 2018

Journal Articles

Novel Role of CEBPÎ² As a Transcriptional Repressor of Transposable Elements

Devi Thiagarajan, Stephen Capone, BS, Anthony Colombo, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD

Blood (2017) 130 (Supplement 1): 771.

https://doi.org/10.1182/blood.V130.Suppl_1.771.771

Published: 2017

Journal Articles

IFN-α Upregulates the Expression of C/EBPβ and Induces Myeloid Differentiation and Exhaustion of CD34 + CML Stem Cells

Asumi Yokota, PhD, Hideyo Hirai, MD, Atsushi Sato, MD, Naoka Kamio, MD, Yoshihiro Hayashi, MD PhD, Yasuo Miura, MD PhD, Shinya Kimura, MD, PhD, Taira Maekawa, MD PhD

Blood (2017) 130 (Supplement 1): 2863.

https://doi.org/10.1182/blood.V130.Suppl_1.2863.2863

Published: 2017

Journal Articles

Altered Enhancer Activity Represses CEBPE Expression in MLL -Rearranged Leukemia

Xianwen Yang, Yuk Man Lam, Wing Chi Lui, Ray K. Ng, PhD

Blood (2017) 130 (Supplement 1): 1207.

https://doi.org/10.1182/blood.V130.Suppl_1.1207.1207

Published: 2017

Journal Articles

C/EBPβ Is a Critical Regulator of CML Stem Cell Differentiation and Exhaustion Induced By Interferon-α

Asumi Yokota, PhD, Hideyo Hirai, MD PhD, Yoshihiro Hayashi, MD PhD, Ryuichi Sato, Hiroko Adachi, Fumiko Sato, Atsushi Sato, MD, Akihiro Tamura, MD PhD, Masaki Iwasa, MD, Aya Fujishiro, MD, Tsukimi Shoji, Takahiro Kashiwagi, Naoka Kamio, MD, Yusuke Torikoshi, MD, Yasuo Miura, MD PhD, Masakazu Nakano, PhD, Kei Tashiro, MD PhD, Taira Maekawa, MD PhD

Blood (2016) 128 (22): 1120.

https://doi.org/10.1182/blood.V128.22.1120.1120

Published: 2016

Journal Articles

Allogeneic Stem Cell Transplantation Improves Survival in Patients with FLT 3-ITD-Negative and NPM 1-Wild Type Intermediate Risk (ELN) Acute Myeloid Leukemia

Blood (2016) 128 (22): 3493.

https://doi.org/10.1182/blood.V128.22.3493.3493

Published: 2016

Journal Articles

C/EBPβ Isoforms Distinctively and Collaboratively Regulate the Behavior of Hematopoietic Stem and Progenitor Cells in Regenerative Conditions

Atsushi Sato, MD, Hideyo Hirai, MD PhD, Asumi Yokota, PhD, Akihiro Tamura, MD, Tsukimi Shoji, Takahiro Kashiwagi, Masaki Iwasa, MD, Aya Fujishiro, MD, Yasuo Miura, MD PhD, Taira Maekawa, MD PhD

Blood (2015) 126 (23): 3580.

https://doi.org/10.1182/blood.V126.23.3580.3580

Published: 2015

Journal Articles

Csf1r Is a Downstream Target of C/EBPβ in Ly6C¯ Monocytes

Akihiro Tamura, MD, Hideyo Hirai, MD PhD, Asumi Yokota, PhD, Atsushi Sato, MD, Tsukimi Shoji, Takahiro Kashiwagi, Masaki Iwasa, MD, Aya Fujishiro, MD, Yasuo Miura, MD PhD, Taira Maekawa, MD PhD

Blood (2015) 126 (23): 994.

https://doi.org/10.1182/blood.V126.23.994.994

Published: 2015

Journal Articles

Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation

Blood (2015) 126 (17): 2062–2069.

https://doi.org/10.1182/blood-2015-06-651562

Published: 2015

Includes: Supplemental data

Journal Articles

A Novel Functional Polymorphism in the CCAAT/Enhancer Binding Protein (C/EBP), Epsilon (CEBPE) Gene Promoter Influences Acute Lymphoblastic Leukemia Risk Via Interaction with IKZF1

Kyle M. Walsh, PhD, Adam J. de Smith, PhD, Jianqiao Xiao, Marcus O. Muench, Marina Fomin, Helen M. Hansen, Catherine Metayer, Joseph L. Wiemels, PhD

Blood (2014) 124 (21): 489.

https://doi.org/10.1182/blood.V124.21.489.489

Published: 2014

Journal Articles

C/EBPβ Promotes Initial Expansion and Exhaustion of Hematopoietic Stem and Progenitor Cells in Response to Hematopoietic Stresses

Atsushi Sato, MD, Hideyo Hirai, MD PhD, Akihiro Tamura, MD, Asumi Yokota, PhD, Yoshihiro Hayashi, MD PhD, Hisayuki Yao, MD PhD, Masaki Iwasa, MD, Aya Fujishiro, MD, Eishi Ashihara, MD PhD, Yasuo Miura, MD PhD, Taira Maekawa, MD PhD

Blood (2014) 124 (21): 5126.

https://doi.org/10.1182/blood.V124.21.5126.5126

Published: 2014

Journal Articles

Essential Roles of C/EBPβ in Survival of Ly6C – monocytes

Akihiro Tamura, MD, Hideyo Hirai, MD PhD, Asumi Yokota, PhD, Atsushi Sato, MD, Hisayuki Yao, MD PhD, Masaki Iwasa, MD, Aya Fujishiro, MD, Yasuo Miura, MD PhD, Taira Maekawa, MD PhD

Blood (2014) 124 (21): 224.

https://doi.org/10.1182/blood.V124.21.224.224

Published: 2014

Journal Articles

Histone Deacetylase 11 (HDAC11) As a Novel Transcriptional Regulator of C/EBP-β, in Immature Myeloid Cell to Myeloid Derived Suppressor Cell Transition

Jie Chen, MA, Eva Sahakian, PhD, John J. Powers, B.S., Maritza LienlafMoreno, BS, Limin Xing, PhD, Susan Deng, Allison Distler, Fengdong Cheng, MD, Alejandro Villagra, PhD, Pedro Horna, MD, Eduardo M. Sotomayor, MD, Javier Pinilla-Ibarz, MD PhD

Blood (2014) 124 (21): 225.

https://doi.org/10.1182/blood.V124.21.225.225

Published: 2014

Journal Articles

A Novel 2 Amino Acids Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency (SGD)

Tadayuki Akagi, PhD, Taizo Wada, MD PhD, Masahiro Muraoka, MD, Tomoko Toma, MD, Kenzo Kaji, MD, Kazunaga Agematsu, MD, H. Phillip Koeffler, MD, Takashi Yokota, PhD, Akihiro Yachie, MD PhD

Blood (2014) 124 (21): 4101.

https://doi.org/10.1182/blood.V124.21.4101.4101

Published: 2014

Journal Articles

Histone Deacetylase 11 (HDAC11) Is a Novel Regulator In The Expansion Of MDSCs Via The Transcription Factor C/EBP-β

Jie Chen, M.A., John Powers, B.S., Jennifer Rock-Klotz, B.S., Susan Deng, B.S., Allison Distler, B.S., Fengdong Cheng, MD, Alejandro Villagra, PhD, Eduardo M. Sotomayor, MD, Eva Sahakian, Ph.D, Javier Pinilla-Ibarz, MD, PhD

Blood (2013) 122 (21): 4887.

https://doi.org/10.1182/blood.V122.21.4887.4887

Published: 2013

Journal Articles

Cytokine-STATs Signalings Upregulate C/EBPβ In BCR-ABL + Leukemic Cells Independently From BCR-ABL/JAK-STAT Pathway

Asumi Yokota, PhD, Hideyo Hirai, MD, PhD, Yoshihiro Hayashi, MD, PhD, Akihiro Tamura, MD, Atsushi Sato, MD, Hisayuki Yao, MD, PhD, Satoshi Yoshioka, MD, Masaki Iwasa, MD, Eishi Ashihara, MD, PhD, Yasuo Miura, MD, PhD, Taira Maekawa, MD, PhD

Blood (2013) 122 (21): 1468.

https://doi.org/10.1182/blood.V122.21.1468.1468

Published: 2013

Journal Articles

Cell-Intrinsic and Cell-Extrinsic Involvement Of C/EBPβ In The Regulation Of Hematopoietic Stem Cells

Akihiro Tamura, MD, Hideyo Hirai, MD, PhD, Yoshihiro Hayashi, MD, PhD, Asumi Yokota, PhD, Atsushi Sato, MD, Satoshi Yoshioka, MD, Masaki Iwasa, MD, Eishi Ashihara, MD, PhD, Yasuo Miura, MD, PhD, Taira Maekawa, MD, PhD

Blood (2013) 122 (21): 1202.

https://doi.org/10.1182/blood.V122.21.1202.1202

Published: 2013

Journal Articles

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

Kiran Tawana, MD, Aline Renneville, Jun Wang, PhD, Panayiotis Georgiades, Xavier Thomas, MD, Valerie Mialou, MD, Aleksander Savic, MD, Frederik W Van Delft, MD PhD, Jennifer G. Treleaven, MD, Sameena Iqbal, Norio Asou, MD, PhD, Naokuni Uike, MD, Konstanze Döhner, MD, Lars Bullinger, MD, PhD, Matthias Stelljes, MD, Csaba Bödör, PhD, James D. Cavenagh, MD, Doris Steinemann, PhD, Tim Ripperger, MD, Brigitte Schlegelberger, MD, PhD, Peter Vandenberghe, MD, PhD, Anne Uyttebroeck, MD, Josep F. Nomdedeu, MD, Henrik Hjorth-Hansen, MD, PhD, Rosemary E Gale, PhD, Cynthia L. Toze, MD, FRCP(C), Michael J. Barnett, BMBS, FRCPC, FRCP, FRCPath, Marianna Zombori, MD, Krisztian Kallay, MD, Jiri Pavlu, MD, Pim Mutsaers, MD, Fred H Menko, MD, Angela Thomas, PhD, FRCPath, FRCP, MB, BS, Christine Wright, MD, Jessica Okosun, MD, Chey Loveday, PhD, Pierre Fenaux, MD, PhD, Hamish Scott, PhD, Claude Preudhomme, Claude Chelala, PhD, Alison Male, MD, Carolyn J. Owen, MD, FRCPC, Matthew Smith, MD, PhD, Jude Fitzgibbon, PhD

Blood (2013) 122 (21): 740.

https://doi.org/10.1182/blood.V122.21.740.740

Published: 2013

NARROW

Identification of a Novel CEBPE Enhancer Essential for Granulocytic Differentiation

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Optimizing Mechanisms for Induction of Immunogenic Cell Death to Improve Patient Outcome in Multiple Myeloma

Novel Role of CEBPÎ² As a Transcriptional Repressor of Transposable Elements

IFN-α Upregulates the Expression of C/EBPβ and Induces Myeloid Differentiation and Exhaustion of CD34 + CML Stem Cells

Altered Enhancer Activity Represses CEBPE Expression in MLL -Rearranged Leukemia

C/EBPβ Is a Critical Regulator of CML Stem Cell Differentiation and Exhaustion Induced By Interferon-α

Allogeneic Stem Cell Transplantation Improves Survival in Patients with FLT 3-ITD-Negative and NPM 1-Wild Type Intermediate Risk (ELN) Acute Myeloid Leukemia

C/EBPβ Isoforms Distinctively and Collaboratively Regulate the Behavior of Hematopoietic Stem and Progenitor Cells in Regenerative Conditions

Csf1r Is a Downstream Target of C/EBPβ in Ly6C¯ Monocytes

Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation

A Novel Functional Polymorphism in the CCAAT/Enhancer Binding Protein (C/EBP), Epsilon (CEBPE) Gene Promoter Influences Acute Lymphoblastic Leukemia Risk Via Interaction with IKZF1

C/EBPβ Promotes Initial Expansion and Exhaustion of Hematopoietic Stem and Progenitor Cells in Response to Hematopoietic Stresses

Essential Roles of C/EBPβ in Survival of Ly6C – monocytes

Histone Deacetylase 11 (HDAC11) As a Novel Transcriptional Regulator of C/EBP-β, in Immature Myeloid Cell to Myeloid Derived Suppressor Cell Transition

A Novel 2 Amino Acids Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency (SGD)

Histone Deacetylase 11 (HDAC11) Is a Novel Regulator In The Expansion Of MDSCs Via The Transcription Factor C/EBP-β

Cytokine-STATs Signalings Upregulate C/EBPβ In BCR-ABL + Leukemic Cells Independently From BCR-ABL/JAK-STAT Pathway

Cell-Intrinsic and Cell-Extrinsic Involvement Of C/EBPβ In The Regulation Of Hematopoietic Stem Cells

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

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