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Journal Articles

Autophagy in Endothelial Cells Regulates Their Hematopoiesis Supporting Ability

Yuan Kong, MD PhD, Xie-Na Cao, Zhong-Shi Lyu, PhD, Xiao-Dong Mo, Qi Wen, MD, Hong-Yan Zhao, MD, Yu-Hong Chen, Yu Wang, Ying-Jun Chang, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang

Blood (2019) 134 (Supplement_1): 4425.

https://doi.org/10.1182/blood-2019-122227

Published: 2019

Journal Articles

Defective Autophagy in MPN Were Predominantly Detected in Megakaryocytes in Philadelphia Negative (Ph -) Myeloproliferative Neoplasm

Jen-Chin Wang, MD, Guanfang Shi, PhD, Karan Josan, MD, Preethi Ramachandran, Vladimir Gotlieb, Gardith Joseph, Sherif A. Nasr, MD

Blood (2019) 134 (Supplement_1): 5386.

https://doi.org/10.1182/blood-2019-127949

Published: 2019

Journal Articles

mTOR Signal Pathway Inhibition Promote the Cytotoxicity of Chemotherapy on SHI-1 Cells

Jing Xu, Zhenjiang Li, Jifu Zheng, Qiong Wu, Qingming Wang, Aiping Tang, Yuan Song, Yan Fei

Blood (2019) 134 (Supplement_1): 5126.

https://doi.org/10.1182/blood-2019-126714

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

Metformin Restores AMPK Alpha-Mediated Autophagy and Prevents Carfilzomib-Induced Cardiotoxicity In Vivo

Georgios Kremastiotis, Panagiotis Efentakis, Aimilia Varela, Constantinos H. Davos, Maria Tsoumani, Georgios Agrogiannis, Anastasia Konstantinidou, Eleni-Dimitra Papanagnou, Ioannis P. Trougakos, Eftathios Kastritis, Zoi Kanaki, Efstathios K. Iliodromitis, Apostolos Klinakis, Meletios A Dimopoulos, MD, Ioanna Andreadou, Evangelos Terpos, MD PhD

Blood (2018) 132 (Supplement 1): 3214.

https://doi.org/10.1182/blood-2018-99-112351

Published: 2018

Journal Articles

Marcks Inhibition By a Peptide Inhibitor, MPS, Cooperates with Bortezomib to Effectively Eliminate Drug Resistance in Multiple Myeloma

Lun Zhang, Nasrin Rastgoo, PhD, Maryam Pourabdollah, MD, Eldad Zacksenhaus, PhD, Yan Chen, MD PhD, Guoan Chen, MD, Hong Chang, MD

Blood (2018) 132 (Supplement 1): 1936.

https://doi.org/10.1182/blood-2018-99-113026

Published: 2018

Journal Articles

MiR-221/222 Promote Dexamethasone Resistance of Multiple Myeloma through Inhibition of Autophagy By Targeting ATG12

Jian Xu, MD, Yan Su, MD, Aoshuang Xu, MD, Fengjuan Fan, PhD, Haifan Huang, MD, Yu Hu, MD PhD, Chunyan Sun, MD PhD

Blood (2018) 132 (Supplement 1): 4469.

https://doi.org/10.1182/blood-2018-99-111637

Published: 2018

Journal Articles

Defective Autophagy Process and Increased ROS Formation in Primary Myelofibrosis

Guanfang Shi, PhD, Sreenath Kodali, MBBS, MD, Ching Wong, MD, Vladimir K. Gotlieb, MD, Jen-Chin Wang, MD

Blood (2018) 132 (Supplement 1): 3069.

https://doi.org/10.1182/blood-2018-99-112406

Published: 2018

Journal Articles

Histone Methyltransferases G9a and GLP; Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma Treatment

Eva De Smedt, Julie Devin, Hui Liu, Anke Maes, Ken Maes, Kim De Veirman, Eline Menu, PhD, Karin Vanderkerken, PhD, Jerome Moreaux, PhD, Elke De Bruyne, PhD

Blood (2017) 130 (Supplement 1): 4356.

https://doi.org/10.1182/blood.V130.Suppl_1.4356.4356

Published: 2017

Journal Articles

Dissecting the Autophagy Tumor Suppressor Pathway Network in Acute Promyelocytic Leukemia Therapy

Magali Humbert, PhD, Elena Federzoni, Mario P. Tschan, PhD

Blood (2016) 128 (22): 1560.

https://doi.org/10.1182/blood.V128.22.1560.1560

Published: 2016

Journal Articles

Non-Canonical Autophagy during APL Therapy

Jing Jin, PhD, Magali Humbert, PhD, Mario P. Tschan, PhD

Blood (2016) 128 (22): 1621.

https://doi.org/10.1182/blood.V128.22.1621.1621

Published: 2016

Journal Articles

The Bioflavinoid Quercetin Induces Apoptosis and Inhibits Autophagy in Primary Acute Lymphoblastic Leukemia in-Vitro

John Mariano, BS, Liana M Toia, BS, Jessica C Shand, MD

Blood (2016) 128 (22): 5148.

https://doi.org/10.1182/blood.V128.22.5148.5148

Published: 2016

Journal Articles

Blocking the Autophagy Pathway As Potential Target for the Treatment of Wild Type P53 AMLs

Hendrik Folkerts, MSc, Susan Hilgendorf, MSc, Albertus T. Wierenga, PhD, Paul J. Coffer, PhD, Jan Jacob Schuringa, PhD, Edo Vellenga, MD PhD

Blood (2016) 128 (22): 770.

https://doi.org/10.1182/blood.V128.22.770.770

Published: 2016

Journal Articles

mTOR Is Dispensable in Hematopoietic Stem Cells and GMP Progenitors, but Plays an Essential Role in the CMP Population, for Autophagy Regulation

Xiaoyi Chen, PhDcandidate, Yi Zheng, PhD, Cuiqing Fan, Song Chen, Jun-lin Guan

Blood (2016) 128 (22): 3864.

https://doi.org/10.1182/blood.V128.22.3864.3864

Published: 2016

Journal Articles

Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma

Mridul Roy, Long Liang, Xiaojuan Xiao, Yuanliang Peng, Yuhao Luo, Weihua Zhou, Ji Zhang, Lugui Qiu, Shuaishuai Zhang, Feng Liu, Xiuli An, MD PhD, Mao Ye, Wen Zhou, PhD, Jing Liu, PhD

Blood (2016) 128 (22): 3265.

https://doi.org/10.1182/blood.V128.22.3265.3265

Published: 2016

Journal Articles

Suppression of Cdc37 Induces Bortezomib Resistance through Autophagy Activation and Plasma Cell Immaturation in Multiple Myeloma

Meirong Zang, Fengyan Jin, Lanting Liu, Gang An, MDPhD, Xiaoqi Qin, MD, Xiaoyan Feng, Yan Xu, MDPhD, Mu Hao, MD PhD, Wen Zhou, PhD, Lugui Qiu, MD PhD

Blood (2015) 126 (23): 2480.

https://doi.org/10.1182/blood.V126.23.2480.2480

Published: 2015

Journal Articles

Beclin-1 Phosphorylation By BCR-ABL Is Crucial for CML Leukemogenesis By Suppression of Autophagy

Chuanjiang Yu, M.S., Sivahari Prasad Gorantla, PhD, Tony Mueller, M.S., Lena Lippert, Zhenyu Yue, PhD, Robert Zeiser, MD, Tobias Huber, MD, Justus Duyster, MD, Anna Lena Illert, MD

Blood (2015) 126 (23): 16.

https://doi.org/10.1182/blood.V126.23.16.16

Published: 2015

Journal Articles

A New AHI-1-DNM2-BCR-ABL Complex Regulates Leukemic Properties of Primitive CML Cells through Mediation of Cellular Endocytosis and ROS-Induced Autophagy

Xiaohu Liu, MSc, Clark Fruhstorfer, BSc, Katharina Rothe, BSc, MSc, Xiaoyan Jiang, MDPhD

Blood (2015) 126 (23): 52.

https://doi.org/10.1182/blood.V126.23.52.52

Published: 2015

Journal Articles

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Anna Polak, MSc, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Dominika Nowis, MDPhD, Jakub Golab, MD PhD, Sebastian Giebel, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 4917.

https://doi.org/10.1182/blood.V126.23.4917.4917

Published: 2015

Journal Articles

Selective Activation of the Non-Classical Estrogen Receptor Gper Elicits Potent Anti-Tumor Activity in Multiple Myeloma

Nicola Amodio, PhD, Enrica Romeo, Maria Angelica Stamato, Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Lavinia Raimondi, Marzia Leotta, Maria Teresa Di Martino, Pierosandro Tagliaferri, MD, Nikhil C. Munshi, MD, Pierfrancesco Tassone, MD

Blood (2015) 126 (23): 916.

https://doi.org/10.1182/blood.V126.23.916.916

Published: 2015

NARROW

Autophagy in Endothelial Cells Regulates Their Hematopoiesis Supporting Ability

Defective Autophagy in MPN Were Predominantly Detected in Megakaryocytes in Philadelphia Negative (Ph -) Myeloproliferative Neoplasm

mTOR Signal Pathway Inhibition Promote the Cytotoxicity of Chemotherapy on SHI-1 Cells

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Metformin Restores AMPK Alpha-Mediated Autophagy and Prevents Carfilzomib-Induced Cardiotoxicity In Vivo

Marcks Inhibition By a Peptide Inhibitor, MPS, Cooperates with Bortezomib to Effectively Eliminate Drug Resistance in Multiple Myeloma

MiR-221/222 Promote Dexamethasone Resistance of Multiple Myeloma through Inhibition of Autophagy By Targeting ATG12

Defective Autophagy Process and Increased ROS Formation in Primary Myelofibrosis

Histone Methyltransferases G9a and GLP; Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma Treatment

Dissecting the Autophagy Tumor Suppressor Pathway Network in Acute Promyelocytic Leukemia Therapy

Non-Canonical Autophagy during APL Therapy

The Bioflavinoid Quercetin Induces Apoptosis and Inhibits Autophagy in Primary Acute Lymphoblastic Leukemia in-Vitro

Blocking the Autophagy Pathway As Potential Target for the Treatment of Wild Type P53 AMLs

mTOR Is Dispensable in Hematopoietic Stem Cells and GMP Progenitors, but Plays an Essential Role in the CMP Population, for Autophagy Regulation

Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma

Suppression of Cdc37 Induces Bortezomib Resistance through Autophagy Activation and Plasma Cell Immaturation in Multiple Myeloma

Beclin-1 Phosphorylation By BCR-ABL Is Crucial for CML Leukemogenesis By Suppression of Autophagy

A New AHI-1-DNM2-BCR-ABL Complex Regulates Leukemic Properties of Primitive CML Cells through Mediation of Cellular Endocytosis and ROS-Induced Autophagy

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Selective Activation of the Non-Classical Estrogen Receptor Gper Elicits Potent Anti-Tumor Activity in Multiple Myeloma

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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