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Journal Articles

Disruption of ADAMTS13-Autoantibody Complexes with an ADAMTS13 Spacer Domain As a Potential Therapeutic Strategy for Immune Thrombotic Thrombocytopenic Purpura

Konstantine Halkidis, MD PhD, X. Long Zheng, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 88.
https://doi.org/10.1182/blood-2019-125965
Published: 2019
Journal Articles

Identification and Characterization of CMV-Specific, HLA-C*07:02 Restricted Antibodies

Moritz Bewarder, MD, Gerhard Held, MD, Lorenz Thurner, MD, Klaus Dieter Preuss, PhD, Gabi Carbon, Birgit Bette, Konstantinos Christofyllakis, MD, Arne Felbel, Dominic Kaddu-Mulindwa, MD, Niels Murawski, MD, Stephan Stilgenbauer, Frank Neumann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5616.
https://doi.org/10.1182/blood-2019-126998
Published: 2019
Journal Articles

Human erythrocyte band 3 is a host receptor for Plasmodium falciparum glutamic acid–rich protein

Haifa Almukadi, Christopher Schwake, Maima M. Kaiser, D. C. Ghislaine Mayer, James Schiemer, Michael R. Baldwin, Shreeya Hegde, Yunzhe Lu, Toshihiko Hanada, Athar H. Chishti
Journal: Blood
Blood (2019) 133 (5): 470–480.
https://doi.org/10.1182/blood-2018-07-865451
Published: 2019
Includes: Supplemental data
Journal Articles

Anti-Human CD117 CAR T-Cells Efficiently Eliminate Hematopoietic Stem and CD117-Positive AML Cells

Renier Myburgh, PhD BSc, MSc, Jonathan Kiefer, Msc, Norman F Russkamp, Dr. MD, Alexander Simonis, Dr. MD, Surema Pfister, C. Matthias Wilk, MD, Chiara Magnani, PhD, Antonia MS Mueller, MD, Burkhard Becher, Prof. Dr., Maries van den Broek, Prof. Dr., Dario Neri, Prof. Dr., Markus G. Manz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4063.
https://doi.org/10.1182/blood-2018-99-118230
Published: 2018
Journal Articles

ALLO-819, an Allogeneic Flt3 CAR T Therapy Possessing an Off-Switch for the Treatment of Acute Myeloid Leukemia

Cesar Sommer, PhD, Ivana Djuretic, PhD, Julien Valton, PhD, Duy Nguyen, Janette Sutton, Kris Poulsen, Julianne Smith, PhD, Ivana Djuretic, PhD, Javier Chaparro-Riggers, PhD, Barbra Sasu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3335.
https://doi.org/10.1182/blood-2018-99-117605
Published: 2018
Journal Articles

A Phage Display-Generated Fully Human Anti-IL-7Rα Antibody Shows Anti-Tumor Activity Against T-Cell Acute Lymphoblastic Leukemia

Padma Akkapeddi, Ana Rita Fragoso, PhD, Julie Hixon, Mariana Oliveira, Tânia Carvalho, Andreas Gloger, Mattia Matasci, Francisco Corzana, Scott Durum, Dario Neri, Prof. Dr., Gonçalo Bernardes, Joao Barata, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1421.
https://doi.org/10.1182/blood-2018-99-116523
Published: 2018
Journal Articles

CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma

Eric L. Smith, MD PhD, Kimberly Harrington, Mette Staehr, PhD, Reed Masakayan, MS, Jon Jones, BS, Thomas Long, PhD, Majid Ghoddusi, DVM, PhD, Terence J Purdon, MS, Trevor Do, Xiuyan Wang, PhD, Minh Pham, Jessica M Brown, Elizabeth Peguero, Carlos Fernández De Larrea, MD PhD, Pei Wang, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Sarah Garrett, Steven Almo, PhD, Isabelle Riviere, PhD, Cheng Liu, PhD, Blythe Duke Sather, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 589.
https://doi.org/10.1182/blood-2018-99-110471
Published: 2018
Journal Articles

Development and Evaluation of CART Targeting Bcma with Humanized Alpaca-Derived Single-Domain Antibody As Antigen Recognition Domain

Lu Han, MS, Quanli Gao, MD, Keshu Zhou, MD, Qingsong Yin, PhD, Baijun Fang, MD, Jian Zhou, MD PhD, Xinghu Zhu, MD, Delong Liu, MD PhD, Jishuai Zhang, PhD, Haoyue Du, Hongjian Li, MS, Yongping Song, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1976.
https://doi.org/10.1182/blood-2018-99-114980
Published: 2018
Journal Articles

Development and Evaluation of a Human Single Chain Variable Fragment (scFv) Derived Bcma Targeted CAR T Cell Vector Leads to a High Objective Response Rate in Patients with Advanced MM

Eric L Smith, MDPhD, Sham Mailankody, MBBS, Arnab Ghosh, MBBS, PhD, Reed Masakayan, MS, Mette Staehr, PhD, Terence J Purdon, MS, Elizabeth Halton, NP, Claudia Diamonte, RN, Pavan Anant, Yvette Bernal, MS, Xiuyan Wang, PhD, Yongzeng Wang, PhD, Sarah Garrett, Steven Almo, PhD, Pei Wang, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Elena Mead, MD, Jae H. Park, MD, Kevin J. Curran, MD, Craig S. Sauter, MD, Sergio A. Giralt, MD, Ola Landgren, MD PhD, Ahmet Dogan, MD PhD, Mikhail Roshal, MDPhD, Cheng Liu, PhD, Isabelle Riviere, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 742.
https://doi.org/10.1182/blood.V130.Suppl_1.742.742
Published: 2017
Journal Articles

Chimeric Antigen Receptor (CAR) T Cells Specific for CD229: A Potentially Curative Approach for Multiple Myeloma

Sabarinath Venniyil Radhakrishnan, MBBS, MD, Tim Luetkens, MD, Sara Yousef, PhD, Neelam Bhardwaj, PhD, Mary Nicole Steinbach, NP, Janet Weidner, Christa Shorter, BSc, Douglas W. Sborov, MD MSc, Djordje Atanackovic, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3142.
https://doi.org/10.1182/blood.V130.Suppl_1.3142.3142
Published: 2017
Journal Articles

Next Generation Sequencing of Immunized Mouse Splenocytes to Develop an Anti-TIM3 Chimeric Antigen Receptor for Acute Myeloid Leukemia

Justin C. Boucher, PhD, Paresh Vishwasrao, Lawrence Guan, Bishwas Shrestha, PhD, Gongbo Li, PhD MBBS, Scott Christley, Lindsay G. Cowell, PhD, Jared Ostmeyer, William H. Rounds, Inimary T. Toby, PhD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2646.
https://doi.org/10.1182/blood.V130.Suppl_1.2646.2646
Published: 2017
Journal Articles

High-Throughput Sequencing of IgG B-Cell Receptors Reveals the Frequent Usage of the Rearranged IGHV4-28//IGHJ4 Gene in Primary Immune Thrombocytopenia in Adults

Naohito Fujishima, MD, Masaru Togashi, MD PhD, Ryo Hasegawa, MD, Ken Watanabe, MD, Akiko Saga, MD PhD, Ayumi Omokawa, MD PhD, Tomoo Saga, MD PhD, Shigeharu Ueki, MD PhD, Naoto Takahashi, Kazutaka Kitaura, DVM, PhD, Ryuji Suzuki, DVM, PhD, Makoto Hirokawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3582.
https://doi.org/10.1182/blood.V130.Suppl_1.3582.3582
Published: 2017
Journal Articles

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

Weixu Meng, MD PhD, Marissa Del Real, PhD, Guowei Wei, PhD, Rochelle Hernandez, Emanuela Marcucci, Allen Lin, Tinisha Mcdonald, Dandan Zhao, MD, Herman Wu, BS, Nadia Carlesso, MD PhD, Larry W Kwak, MDPhD, Ling Li, PhD, Ya-Huei Kuo, PhD, Anthony S. Stein, MD, Vinod Pullarkat, MD MRCP, Ryotaro Nakamura, MD, Steven T. Rosen, MD, Stephen J. Forman, MD FACP, Bin Zhang, PhD, Lihua Budde, MD PhD, Guido Marcucci, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1361.
https://doi.org/10.1182/blood.V130.Suppl_1.1361.1361
Published: 2017
Journal Articles

Bispecific Antibodies with Native Human IgG Structure As Mimetics for FVIII Activity

Sabine Knappe, PhD, Nicolas Fischer, Patrice Robert Douillard, Rudolf Hartmann, PhD, Gerald Schrenk, PhD, Ulla Ravn, Giovanni Magistrelli, Franck Gueneau, Gerard Didelot, Krzysztof Masternak, Marie Kosco-Vilbois, Friedrich Scheiflinger, PhD, Michael Dockal, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1083.
https://doi.org/10.1182/blood.V130.Suppl_1.1083.1083
Published: 2017
Journal Articles

FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII

Jeongheon Yoon, Anja Schmidt, Ai-Hong Zhang, Christoph Königs, Yong Chan Kim, David W. Scott
Journal: Blood
Blood (2017) 129 (2): 238–245.
https://doi.org/10.1182/blood-2016-07-727834
Published: 2017
Journal Articles

Development of Platforms to Phenotype Variants of Uncertain Significance in VWF

Andrew Yee, PhD, Manhong Dai, Colin Kretz, PhD, Fan Meng, PhD, David Ginsburg, MD
Journal: Blood
Blood (2016) 128 (22): 1386.
https://doi.org/10.1182/blood.V128.22.1386.1386
Published: 2016
Journal Articles

Anti-CD19 ARTEMIS TM Therapy Drastically Reduces Cytokine Release without Compromising Efficacy Against Preclinical Lymphoma Models

Hong Liu, PhD, Li Long, MD PhD, Shon Green, PhD, Lucas H Horan, PhD, Bryan Zimdahl, PhD, Cheng Liu, PhD
Journal: Blood
Blood (2016) 128 (22): 3354.
https://doi.org/10.1182/blood.V128.22.3354.3354
Published: 2016
Journal Articles

Trafficking of Plasmodium Falciparum Proteins: A Novel Anti-Malaria Drug Target?

Theresa L. Coetzer, PhD, Alisje Churchyard, BSc Hons, Melanie Wepener, MSc
Journal: Blood
Blood (2016) 128 (22): 2443.
https://doi.org/10.1182/blood.V128.22.2443.2443
Published: 2016
Journal Articles

CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate

Daniel W. Sherbenou, MD PhD, Blake T. Aftab, PhD, Yang Su, PhD, Christopher R. Behrens, PhD, Arun P. Wiita, MD PhD, Aaron C. Logan, MD PhD, Diego Acosta-Alvear, PhD, Byron C. Hann, MD PhD, Peter Walter, PhD, Xiaobo Wu, MD, John P. Atkinson, MD, Jeffrey L. Wolf, MD, Thomas G. Martin, III, MD, Bin Liu, PhD
Journal: Blood
Blood (2016) 128 (22): 384.
https://doi.org/10.1182/blood.V128.22.384.384
Published: 2016
Journal Articles

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

Pavan K. Bendapudi, MD, Karen Deceunynck, PhD, Secil Koseoglu, PhD, Roelof Hendrik Bekendam, MD, Shauna D Mason, Jon Kenniston, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2016) 128 (22): 258.
https://doi.org/10.1182/blood.V128.22.258.258
Published: 2016