Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 30

Sort by

Sort Order Select

Journal Articles

Glutamine Depletion By Addicted Myeloma Cells Inhibits Osteoblastic Differentiation of Bone Marrow Mesenchymal Stromal Cells Limiting Asparagine Availability: A Possible New Mechanism for Myeloma Bone Disease

Martina Chiu, PhD, Denise Toscani, PhD, Emanuela Vicario, PhD, Roberta Andreoli, PhD, Giuseppe Taurino, MS, Valentina Marchica, MS, Paola Storti, PhD, Massimiliano Bianchi, PhD, Ovidio Bussolati, MD PhD, Nicola Giuliani

Blood (2019) 134 (Supplement_1): 4339.

https://doi.org/10.1182/blood-2019-128034

Published: 2019

Journal Articles

Contribution of Amino Acid Metabolism to Hematologic Malignancies

Marina Y. Konopleva, MD PhD, Philip L Lorenzi, PhD, Sanaz Ghotbaldini, Yoko Tabe, MD PhD, Tianyu Cai, PhD, Stefano Tiziani, PhD

Blood (2018) 132 (Supplement 1): SCI-10.

https://doi.org/10.1182/blood-2018-99-109469

Published: 2018

Journal Articles

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Laura Hinze, Maren Pfirrmann, Salmaan Karim, James Degar, Connor McGuckin, Divya Vinjamur, PhD, Sacher Joshua, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Daniel E. Bauer, MD PhD, Florence Wagner, PhD, Kimberly Stegmaier, MD, Alejandro Gutierrez, MD

Blood (2018) 132 (Supplement 1): 891.

https://doi.org/10.1182/blood-2018-99-113794

Published: 2018

Journal Articles

The Glutaminase Activity of L-Asparaginase Mediates Suppression of Asns Upregulation

Wai Kin Chan, PhD, Lin Tan, MS, Karine Harutyunyan, PhD, Di Du, PhD, Leona Martin, MS, Eric Yin, MS, Marina Y. Konopleva, MD PhD, John Weinstein, MD PhD, Philip L Lorenzi, PhD

Blood (2018) 132 (Supplement 1): 3959.

https://doi.org/10.1182/blood-2018-99-117818

Published: 2018

Journal Articles

Aspariginase-Triggered Hyperglycerimedia: An Analysis on Germline Regulatory Gene Variations in Adult Acute Lymphoblastic Leukemia Patients

Sari Kytölä, MD, Suvi Rantamo, MSc, Matti Jauhiainen, PhD, Kimmo Porkka, MD PhD, Outi Kilpivaara, PhD, Ulla Wartiovaara-Kautto, MD PhD

Blood (2017) 130 (Supplement 1): 1287.

https://doi.org/10.1182/blood.V130.Suppl_1.1287.1287

Published: 2017

Journal Articles

Involvement of Allele-Specific Methylation of Asparagine Synthetase Gene in Asparaginase Sensitivity of BCP-ALL

Atsushi Watanabe, MD PhD, Takeshi Inukai, MD, PhD, Minori Tamai, MD PhD, Tamao Shinohara, MD, Shinpei Somazu, MD, Hiroko Oshiro, MD PhD, Koshi Akahane, MD PhD, Kumiko Goi, MD,PhD, Kunio Miyake, PhD, Kevin Urayama, PhD MPH, Kanji Sugita, MD, PhD

Blood (2016) 128 (22): 3966.

https://doi.org/10.1182/blood.V128.22.3966.3966

Published: 2016

Journal Articles

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

Aysenur Esen, MD, Anwar A Khan, PhD, Jason Chan, Nadim Mahmud, MD PhD, John G. Quigley, MD

Blood (2016) 128 (22): 4716.

https://doi.org/10.1182/blood.V128.22.4716.4716

Published: 2016

Journal Articles

Astarabine, a Cytarabine Pro-Drug, Is Safe and Efficacious in the Treatment of Leukemia - Results of Animal Studies

Stela Gengrinovitch, PhD, Ruth Ben Yakar, PhD, Tsila Zuckerman, MD, Norberto Krivoy, MD, Jacob M. Rowe, MD

Blood (2015) 126 (23): 2545.

https://doi.org/10.1182/blood.V126.23.2545.2545

Published: 2015

Journal Articles

L-Asparaginase Ex Vivo Activity Distorts Plasmatic Asparagine Depletion Assessment

Willy Berlier, PhD, Yann Godfrin, PhD

Blood (2014) 124 (21): 5357.

https://doi.org/10.1182/blood.V124.21.5357.5357

Published: 2014

Journal Articles

Asparagine Synthetase Expression and L-Asparaginase Sensitivity in Aggressive Lymphomas

Willy Berlier, PhD, Karine Aguera, Anne-Marie Chevrier, Fanny Gallix, Alexandra Traverse-Glehen, MD PhD, Gilles Salles, MD PhD, Yann Godfrin, PhD

Blood (2014) 124 (21): 5494.

https://doi.org/10.1182/blood.V124.21.5494.5494

Published: 2014

Journal Articles

L-Asparaginase Causes Metabolic Reprogramming in ALL Cells

Ivana Hermanova, Karel Valis, PhD, Hana Nuskova, Meritxell Alberich-Jorda, PhD, Amaia Arruabarrena Aristorena, Sonia Fernández-Ruiz, Simona Bartova, Alena Pecinova, PhD, Daniel Kavan, PhD, Karel Fiser, PhD, Marek Kuzma, PhD, Petr Novak, PhD, Tomas Mracek, PhD, Arkaitz Carracedo, PhD, Jan Trka, MD, PhD, Prof., Julia Starkova

Blood (2014) 124 (21): 922.

https://doi.org/10.1182/blood.V124.21.922.922

Published: 2014

Journal Articles

Ammonium Production and Glutamine-Addiction of Myeloma Cells: New Attractive Targets in Multiple Myeloma

Fabrizio Accardi, MD, Martina Chiu, Marina Bolzoni, Paola Storti, PhD, Katia Todoerti, PhD, Luca Agnelli, Massimiliano Ferrari, MD, Gabriele Missale, MD, Franco Aversa, MD, Ovidio Bussolati, MD PhD, Nicola Giuliani, MD PhD

Blood (2014) 124 (21): 2067.

https://doi.org/10.1182/blood.V124.21.2067.2067

Published: 2014

Journal Articles

Flow Cytometric Detection of Asparagine Synthetase Protein in Leukemia Cells; Indication for L-Asparaginase Therapy

Toshiyuki Kitoh, MD PhD, Kou Suchan Gao Siqiang, MSMT, Hidefumi Kato, MD PhD, Kenji Miyata, MD, Yasuto Shimomura, MD PhD, Toshinori Hori, MD PhD, Kimiyoshi Sakaguchi, MD, Yasuo Horikoshi, MD, Kentarou Ohki, MD, Katsuyoshi Koh, MD PhD, Takao Hamakubo, MD PhD

Blood (2014) 124 (21): 2233.

https://doi.org/10.1182/blood.V124.21.2233.2233

Published: 2014

Journal Articles

The Glutaminase Activity Of L-Asparaginase Is Not Required For Anticancer Activity Against Asns-Negative Cell Lines

Philip L Lorenzi, Wai Kin Chan, Andriy Anishkin, Preeti Purwaha, David M Rogers, Sergei Sukharev, Susan B Rempe, John N Weinstein

Blood (2013) 122 (21): 4912.

https://doi.org/10.1182/blood.V122.21.4912.4912

Published: 2013

Journal Articles

L-Asparaginase Sensitivity and Asparagine Synthetase Expression In Primary Tumor Cells From AML Patients

Willy Berlier, PhD, Karine Aguera, Mohamed El Hamri, PhD, Marie-Pierre Goutagny, Fanny Gallix, Yves Bertrand, MD, Xavier Thomas, MD, Yann Godfrin, PhD

Blood (2013) 122 (21): 1423.

https://doi.org/10.1182/blood.V122.21.1423.1423

Published: 2013

Journal Articles

Global Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes In Natural Killer Cell Lymphomas

Can Kucuk, PhD, Xiaozhou Hu, M.D., Bei Jiang, Philippe Gaulard, MD, David Klinkebiel, Ph.D., Huimin Geng, PhD, Alyssa Bouska, Ph.D., Javeed Iqbal, M.Sc, PhD, Timothy McKeithan, MD, PhD, Wing C. Chan, MD

Blood (2013) 122 (21): 1262.

https://doi.org/10.1182/blood.V122.21.1262.1262

Published: 2013

Journal Articles

L-Asparaginase Strongly Affects Bioenergetics in Leukemic Cells

Ivana Hermanova, Karel Valis, PhD, Karel Fiser, PhD, Hana Nuskova, Jan Trka, MD, PhD, Julia Starkova, PhD

Blood (2012) 120 (21): 779.

https://doi.org/10.1182/blood.V120.21.779.779

Published: 2012

Journal Articles

Blast Asparagine Synthetase Deficiency in Acute Myeloid Leukemia

Willy Berlier, PhD, Mohamed El Hamri, PhD, Karine Aguera, Yannick Campion, Fabien Gay, PhD, Yann Godfrin, PhD, Xavier Thomas, MD

Blood (2012) 120 (21): 4333.

https://doi.org/10.1182/blood.V120.21.4333.4333

Published: 2012

Journal Articles

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia

Julie Rousseau, Vincent Gagné, Malgorzata Labuda, Cyrielle Beaubois, Daniel Sinnett, Caroline Laverdière, Albert Moghrabi, Stephen E. Sallan, Lewis B. Silverman, Donna Neuberg, Jeffery L. Kutok, Maja Krajinovic

Blood (2011) 118 (22): 5883–5890.

https://doi.org/10.1182/blood-2011-05-355560

Published: 2011

Includes: Supplemental data

Journal Articles

Investigating the Potential Use of L-Asparaginase in Myeloid Leukemia,

Sung Ah Jun, Lusia Sepiashvili, Thomas Kislinger, PhD, Mark D. Minden, MD, PhD

Blood (2011) 118 (21): 3641.

https://doi.org/10.1182/blood.V118.21.3641.3641

Published: 2011

NARROW

Glutamine Depletion By Addicted Myeloma Cells Inhibits Osteoblastic Differentiation of Bone Marrow Mesenchymal Stromal Cells Limiting Asparagine Availability: A Possible New Mechanism for Myeloma Bone Disease

Contribution of Amino Acid Metabolism to Hematologic Malignancies

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

The Glutaminase Activity of L-Asparaginase Mediates Suppression of Asns Upregulation

Aspariginase-Triggered Hyperglycerimedia: An Analysis on Germline Regulatory Gene Variations in Adult Acute Lymphoblastic Leukemia Patients

Involvement of Allele-Specific Methylation of Asparagine Synthetase Gene in Asparaginase Sensitivity of BCP-ALL

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

Astarabine, a Cytarabine Pro-Drug, Is Safe and Efficacious in the Treatment of Leukemia - Results of Animal Studies

L-Asparaginase Ex Vivo Activity Distorts Plasmatic Asparagine Depletion Assessment

Asparagine Synthetase Expression and L-Asparaginase Sensitivity in Aggressive Lymphomas

L-Asparaginase Causes Metabolic Reprogramming in ALL Cells

Ammonium Production and Glutamine-Addiction of Myeloma Cells: New Attractive Targets in Multiple Myeloma

Flow Cytometric Detection of Asparagine Synthetase Protein in Leukemia Cells; Indication for L-Asparaginase Therapy

The Glutaminase Activity Of L-Asparaginase Is Not Required For Anticancer Activity Against Asns-Negative Cell Lines

L-Asparaginase Sensitivity and Asparagine Synthetase Expression In Primary Tumor Cells From AML Patients

Global Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes In Natural Killer Cell Lymphomas

L-Asparaginase Strongly Affects Bioenergetics in Leukemic Cells

Blast Asparagine Synthetase Deficiency in Acute Myeloid Leukemia

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia

Investigating the Potential Use of L-Asparaginase in Myeloid Leukemia,

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only