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Journal Articles

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Layla Van Doren, MD, Nga Nguyen, BSc, Chris Garzia, BSc, Elizabeth Fletcher, PhD, Ryan Stevenson, MD, David Jaramillo, MSc, Athan Kuliopulos, MD PhD, Lidija Covic, PhD

Blood (2019) 134 (Supplement_1): 1064.

https://doi.org/10.1182/blood-2019-126111

Published: 2019

Journal Articles

PCTP (Phosphatidylcholine Transfer Protein) is Regulated By RUNX1 in Platelets/Megakaryocytes and is Associated with Adverse Cardiovascular Events

Natthapol Songdej, MD MPH, Guangfen Mao, MD, Deepak Voora, MD, Lawrence E. Goldfinger, PhD, Fabiola Del Carpio-Cano, Rachel Myers, Angara Koneti Rao, MBBS

Blood (2016) 128 (22): 365.

https://doi.org/10.1182/blood.V128.22.365.365

Published: 2016

Journal Articles

Potent Anti-Platelet Metabolite, 12-HETrE, Inhibits Platelet Activation and Thrombosis In Vivo Via Activation of the IP Receptor

Benjamin Tourdot, PhD, Zitha Isingizwe, BS, Jennifer Yeung, Reheman Adili, MD, Michael Holinstat, PhD

Blood (2016) 128 (22): 714.

https://doi.org/10.1182/blood.V128.22.714.714

Published: 2016

Journal Articles

Transcription Factor RUNX1 Regulates Pctp (Phosphatidylcholine Transfer Protein) in Platelets: A Potential Role in Regulating Platelet Function

Natthapol Songdej, MD MPH, Guangfen Mao, MD, Lawrence E. Goldfinger, PhD, Angara Koneti Rao, MD

Blood (2015) 126 (23): 2247.

https://doi.org/10.1182/blood.V126.23.2247.2247

Published: 2015

Journal Articles

Novel 12-LOX Inhibitor ML355 Attenuates Platelet Reactivity and Impairs Thrombus Growth, Stability and Vessel Occlusion In Vivo

Reheman Adili, MD, Theodore R Holman, PhD, Michael Holinstat, PhD

Blood (2015) 126 (23): 3442.

https://doi.org/10.1182/blood.V126.23.3442.3442

Published: 2015

Journal Articles

12-HETrE, a Novel 12-LOX Oxylipin, Prevents Platelet Activation in a Gα s -like Manner

Jennifer Yeung, MS, Pilar Fernandez-Perez, BS, Joanne Vesci, MLT, Theodore R Holman, PhD, Jin Ren, PhD, Michael Holinstat, PhD

Blood (2014) 124 (21): 1436.

https://doi.org/10.1182/blood.V124.21.1436.1436

Published: 2014

Journal Articles

12-Lipoxygenase Regulates Platelet Reactivity and Thrombosis Through Formation Of Unique Oxylipins

Jennifer Yeung, MS, Pilar Fernandez-Perez, MS, Joanne Vesci, MLT, Theodore R Holman, PhD, Michael Holinstat, PhD

Blood (2013) 122 (21): 3515.

https://doi.org/10.1182/blood.V122.21.3515.3515

Published: 2013

Journal Articles

RUNX1 Regulates PLDN (Pallidin) Expression In Platelets: A Potential Mechanism For Dense Granule Deficiency In RUNX1 Haplodeficiency

Guangfen Mao, MD, Chengxiang Fan, MD, PhD, Gauthami Jalagadugula, PhD, Robert Freishtat, MD, A. Koneti Rao, MD

Blood (2013) 122 (21): 567.

https://doi.org/10.1182/blood.V122.21.567.567

Published: 2013

Journal Articles

12-HETrE, An Endogenous Inhibitor of Platelet Activation,

Jennifer Yeung, Kenneth Ikei, Joanne Vesci, MLT, Alex Arnouk, Theodore R Holman, PhD, Michael Holinstat, PhD

Blood (2011) 118 (21): 3254.

https://doi.org/10.1182/blood.V118.21.3254.3254

Published: 2011

Journal Articles

Platelet 12-Lipoxygenase Is Required for Dense Granule Secretion and Platelet Aggregation: Role of 12-hLO In Platelet Hemostasis and Thrombosis

Patrick Apopa, PhD, Megha Patel, B.S., Olivier Boutaud, PhD, Michael Holinstat, PhD

Blood (2010) 116 (21): 3203.

https://doi.org/10.1182/blood.V116.21.3203.3203

Published: 2010

Journal Articles

The Effect of Anti-GPIIIa49-66 Antibody on Megakaryocyte Differentiation.

Jianhui Wang, MS, Ruimin Pan, PhD, Michael A. Nardi, MS, Zongdong Li, PhD

Blood (2010) 116 (21): 1434.

https://doi.org/10.1182/blood.V116.21.1434.1434

Published: 2010

Journal Articles

RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene ( ALOX12 ): studies in human RUNX1 haplodeficiency

Gurpreet Kaur, Gauthami Jalagadugula, Guangfen Mao, A. Koneti Rao

Blood (2010) 115 (15): 3128–3135.

https://doi.org/10.1182/blood-2009-04-214601

Published: 2010

Journal Articles

The Orphan Receptor GPR31 Is the Platelet and HUVEC Receptor for 12(S)-HETE

Steven J Feinmark, Michael A. Nardi, Erin Harleton, Liang Hu, Ruimin Pan, Simon Karpatkin

Blood (2008) 112 (11): 413.

https://doi.org/10.1182/blood.V112.11.413.413

Published: 2008

Journal Articles

A New Mechanism of Platelet Activation and Oxidative Death Induced by ADAMTS-18 and Regulating Bleeding Time.

Zongdong Li, MD, Michael Nardi, MS, Ruimin Pan, PhD, Herman Yee, MD, Simon Karpatkin, MD

Blood (2007) 110 (11): 133.

https://doi.org/10.1182/blood.V110.11.133.133

Published: 2007

Journal Articles

CBFA2/RUNX1 Regulates Human Platelet 12-Lipoxygenase: Studies in Runx1 Haplodeficiency.

Gurpreet Kaur, PhD, Gauthami Jalagadugula, PhD, A. Koneti Rao, MD

Blood (2007) 110 (11): 3648.

https://doi.org/10.1182/blood.V110.11.3648.3648

Published: 2007

Journal Articles

Platelet particle formation by anti–GPIIIa49-66 Ab, Ca 2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A 2 , 12-lipoxygenase, and NADPH oxidase

Michael A. Nardi, Yelena Gor, Steven J. Feinmark, Fang Xu, Simon Karpatkin

Blood (2007) 110 (6): 1989–1996.

https://doi.org/10.1182/blood-2006-10-054064

Published: 2007

Journal Articles

Dexamethasone (Dex) Inhibits Anti-GPIIIa49-66 Ab Induced Oxidative Fragmenation of Platelets: Inhibition of Platelet Phospholipase A 2 (PLA 2 ) and 12-Lipoxygenase (12-LO) MembraneTranslocation and Activity.

Michael A. Nardi, Steven J. Feinmark, Yelena Gor, Simon Karpatkin

Blood (2006) 108 (11): 1512.

https://doi.org/10.1182/blood.V108.11.1512.1512

Published: 2006

Journal Articles

A New Mechanism of Platelet Activation, Oxidation and Death Induced by ADAMTS-18.

Zongdong Li, PhD, Michael A. Nardi, MS, Steven J. Feinmark, MD, Simon Karpatkin, MD

Blood (2005) 106 (11): 652.

https://doi.org/10.1182/blood.V106.11.652.652

Published: 2005

Journal Articles

Decreased Platelet Expression of MYL9 (Myosin Regulatory Light Chain Polypeptide) and Other Genes with Platelets Dysfunction and CBFA2 Mutation: Insights from Platelet Expression Profiling.

Liansheng Sun, MD, J. Rafael Gorospe, MD, PhD, Eric P. Hoffman, PhD, A. Koneti Rao, MD

Blood (2004) 104 (11): 737.

https://doi.org/10.1182/blood.V104.11.737.737

Published: 2004

Journal Articles

Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase

Daotai Nie, Keqin Tang, Clement Diglio, Kenneth V. Honn

Blood (2000) 95 (7): 2304–2311.

https://doi.org/10.1182/blood.V95.7.2304

Published: 2000

NARROW

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

PCTP (Phosphatidylcholine Transfer Protein) is Regulated By RUNX1 in Platelets/Megakaryocytes and is Associated with Adverse Cardiovascular Events

Potent Anti-Platelet Metabolite, 12-HETrE, Inhibits Platelet Activation and Thrombosis In Vivo Via Activation of the IP Receptor

Transcription Factor RUNX1 Regulates Pctp (Phosphatidylcholine Transfer Protein) in Platelets: A Potential Role in Regulating Platelet Function

Novel 12-LOX Inhibitor ML355 Attenuates Platelet Reactivity and Impairs Thrombus Growth, Stability and Vessel Occlusion In Vivo

12-HETrE, a Novel 12-LOX Oxylipin, Prevents Platelet Activation in a Gα s -like Manner

12-Lipoxygenase Regulates Platelet Reactivity and Thrombosis Through Formation Of Unique Oxylipins

RUNX1 Regulates PLDN (Pallidin) Expression In Platelets: A Potential Mechanism For Dense Granule Deficiency In RUNX1 Haplodeficiency

12-HETrE, An Endogenous Inhibitor of Platelet Activation,

Platelet 12-Lipoxygenase Is Required for Dense Granule Secretion and Platelet Aggregation: Role of 12-hLO In Platelet Hemostasis and Thrombosis

The Effect of Anti-GPIIIa49-66 Antibody on Megakaryocyte Differentiation.

RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene ( ALOX12 ): studies in human RUNX1 haplodeficiency

The Orphan Receptor GPR31 Is the Platelet and HUVEC Receptor for 12(S)-HETE

A New Mechanism of Platelet Activation and Oxidative Death Induced by ADAMTS-18 and Regulating Bleeding Time.

CBFA2/RUNX1 Regulates Human Platelet 12-Lipoxygenase: Studies in Runx1 Haplodeficiency.

Platelet particle formation by anti–GPIIIa49-66 Ab, Ca 2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A 2 , 12-lipoxygenase, and NADPH oxidase

Dexamethasone (Dex) Inhibits Anti-GPIIIa49-66 Ab Induced Oxidative Fragmenation of Platelets: Inhibition of Platelet Phospholipase A 2 (PLA 2 ) and 12-Lipoxygenase (12-LO) MembraneTranslocation and Activity.

A New Mechanism of Platelet Activation, Oxidation and Death Induced by ADAMTS-18.

Decreased Platelet Expression of MYL9 (Myosin Regulatory Light Chain Polypeptide) and Other Genes with Platelets Dysfunction and CBFA2 Mutation: Insights from Platelet Expression Profiling.

Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase

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American Society of Hematology

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American Society of Hematology

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