Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 40

Sort by

Sort Order Select

Journal Articles

Molecular Characterization and Novel Therapeutic Strategy for X-Linked Sideroblastic Anemia Associated with ALAS2 Missense Variants

Koya Ono, MD, Tohru Fujiwara, MD PhD, Kei Saito, MD PhD, Chie Suzuki, Noriyuki Takahashi, Koichi Onodera, MD PhD, Satoshi Ichikawa, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3530.

https://doi.org/10.1182/blood-2019-124810

Published: 2019

Journal Articles

An Orchestrated Balance between Mitochondria Biogenesis, Iron-Sulfur Cluster Synthesis and Cellular Iron Acquisition

Ping La, Valentina Ghiaccio, PhD, Jianbing Zhang, PhD, Stefano Rivella

Blood (2018) 132 (Supplement 1): 1048.

https://doi.org/10.1182/blood-2018-99-112198

Published: 2018

Journal Articles

AMPK Regulates the Expression of the Fe-S Cluster Assembly Enzyme (ISCU) and ALAS2, Modulating Cellular Iron Metabolism and Increasing Hemoglobin Synthesis

Ping La, Silvia Pires Lourenco, MSc, Laura Breda, PhD, Stefano Rivella

Blood (2018) 132 (Supplement 1): 851.

https://doi.org/10.1182/blood-2018-99-112175

Published: 2018

Journal Articles

Explore: A Prospective, Multinational Natural History Study of Patients with Acute Hepatic Porphyrias (AHP) with Recurrent Attacks

Blood (2017) 130 (Supplement 1): 2211.

https://doi.org/10.1182/blood.V130.Suppl_1.2211.2211

Published: 2017

Journal Articles

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

Kei Saito, Tohru Fujiwara, MD PhD, Shunsuke Hatta, MD PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Yukio Nakamura, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 171.

https://doi.org/10.1182/blood.V130.Suppl_1.171.171

Published: 2017

Journal Articles

Endothelial Cell-Selective Adhesion Molecule (ESAM) Plays Important Roles in the Adult-Type Hemoglobin Synthesis during Fetal Erythropoiesis

Tomoaki Ueda, Takafumi Yokota, MD PhD, Yasuhiro Shingai, Yukiko Doi, Tomohiko Ishibashi, Takao Sudo, Akira Tanimura, Michiko Ichii, MD PhD, Sachiko Ezoe, Hirohiko Shibayama, MD PhD, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2017) 130 (Supplement 1): 1157.

https://doi.org/10.1182/blood.V130.Suppl_1.1157.1157

Published: 2017

Journal Articles

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Daniel Garcia dos Santos, PhD, Amel Hamdi, PhD, Prem Ponka, MD PhD

Blood (2017) 130 (Supplement 1): 3494.

https://doi.org/10.1182/blood.V130.Suppl_1.3494.3494

Published: 2017

Journal Articles

Role of Heme in the Regulation of Transferrin Receptor Expression in Erythroid Cells

Amel Hamdi, PhD, Daniel Garcia dos Santos, PhD, Chun-Nam Lok, PhD, Matthias Schranzhofer, PhD, Prem Ponka, MD PhD

Blood (2017) 130 (Supplement 1): 3495.

https://doi.org/10.1182/blood.V130.Suppl_1.3495.3495

Published: 2017

Journal Articles

The Role of TCA Cycle Compounds in Erythroid Heme Synthesis and Its Regulation During an Inflammatory Response

Jason R. Marcero, BS, Joseph S. Burch, PhD, John D. Phillips, PhD, James E. Cox, PhD, Laurie K. Jackson, PhD, Harry A. Dailey, PhD

Blood (2017) 130 (Supplement 1): 3473.

https://doi.org/10.1182/blood.V130.Suppl_1.3473.3473

Published: 2017

Journal Articles

Mutation of a GATA1 Binding Site in ALAS2 Intron 1 Arrests Murine Erythroid Development In Vivo

Yingchi Zhang, Jingliao Zhang, Wenbin An, Yang Wan, MD, Jie Gao, Lihong Shi, Tao Cheng, MD, Xiaofan Zhu, MD

Blood (2016) 128 (22): 2425.

https://doi.org/10.1182/blood.V128.22.2425.2425

Published: 2016

Journal Articles

Interim Data from a Randomized, Placebo Controlled, Phase 1 Study of Aln-AS1, an Investigational RNAi Therapeutic for the Treatment of Acute Hepatic Porphyria

Eliane Sardh, MD PhD, Pauline Harper, MD PhD, Nabil Al-Tawil, MD, Manisha Balwani, MD MS, Karl Anderson, MD, Joseph Bloomer, MD, D. Montgomery Bissel, MD, Robert J. Desnick, MD, Charles J. Parker, MD, John D. Phillips, PhD, Herbert L. Bonkovsky, MD, Craig Penz, MA, Amy Chan, PhD, Chang-Heok Soh, PhD, William Querbes, PhD, Amy Simon, MD, Penelope Stein, MD PhD, David C. Rees, FRCP, FRCPath, MA, MBBS

Blood (2016) 128 (22): 2318.

https://doi.org/10.1182/blood.V128.22.2318.2318

Published: 2016

Journal Articles

The Interplay of GATA1 with Heme Regulates an Erythroid Cell's Differentiation

Raymond T Doty, PhD, Xiaowei Yan, PhD, Christopher Lausted, MS, Zhantao Yang, MD, Li Liu, PhD, Neda Jabbari, PhD, Siobán B. Keel, MD, Qiang Tian, MD PhD, Janis L. Abkowitz, MD

Blood (2016) 128 (22): 541.

https://doi.org/10.1182/blood.V128.22.541.541

Published: 2016

Journal Articles

Endothelial Cell-Selective Adhesion Molecule (ESAM) Is Required for the Ontogeny of Definitive Hematopoietic System in Mice

Tomoaki Ueda, MD, Takafumi Yokota, MD PhD, Yasuhiro Shingai, MD, Yukiko Doi, MD, Tomohiko Ishibashi, MD PhD, Takao Sudo, MD PhD, Yasuhiro Nagate, MD, Akira Tanimura, MD PhD, Masahiro Tokunaga, MD PhD, Jiro Fujita, MD PhD, Michiko Ichii, MD PhD, Sachiko Ezoe, MD PhD, Hirohiko Shibayama, MDPhD, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2016) 128 (22): 3874.

https://doi.org/10.1182/blood.V128.22.3874.3874

Published: 2016

Journal Articles

Generation of Induced Pluripotent Stem Cell-Derived Erythroblasts from a Patient with X-Linked Sideroblastic Anemia

Shunsuke Hatta, MD, PhD, Tohru Fujiwara, MD, PhD, Takako Yamamoto, Mayumi Kamata, MD, Yoshiko Tamai, Yukio Nakamura, MD, PhD, Shin Kawamata, Hideo Harigae, MD PhD

Blood (2016) 128 (22): 76.

https://doi.org/10.1182/blood.V128.22.76.76

Published: 2016

Journal Articles

Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation

Yvette Y Yien, PhD, Caiyong Chen, PhD, Jiahai Shi, PhD, Liangtao Li, PhD, Daniel E. Bauer, MD, PhD, Nicholas Huston, Paul D. Kingsley, PhD, Julien Ablain, Leonard I Zon, MD, James Palis, MD, Stuart H. Orkin, MD, Jerry Kaplan, PhD, John D Phillips, PhD, Harvey F. Lodish, PhD, Barry Paw, MD, PhD

Blood (2015) 126 (23): 405.

https://doi.org/10.1182/blood.V126.23.405.405

Published: 2015

Journal Articles

Mechanism Governing Heme Synthesis Reveals a GATA Factor-Heme Circuit That Controls Differentiation

Emery H Bresnick, PhD, Nobuyuki Tanimura, Eli Miller, Kazuhiko Igarashi, MD PhD, David T Yang, MD, Judith Burstyn, Colin Dewey

Blood (2015) 126 (23): 161.

https://doi.org/10.1182/blood.V126.23.161.161

Published: 2015

Journal Articles

Transcriptional Induction of Transferrin Receptors By Heme in Erythroid Cells

Daniel Garcia dos Santos, PhD, Matthias Schranzhofer, MSc, PhD, Nam Lok Chun, PhD, Amel Hamdi, PhD, Prem Ponka, MD PhD FCMA

Blood (2015) 126 (23): 3352.

https://doi.org/10.1182/blood.V126.23.3352.3352

Published: 2015

Journal Articles

Exploring the Potential Usefulness of 5-Aminolevulinic Acid for X-Linked Sideroblastic Anemia

Tohru Fujiwara, MD PhD, Ryoyu Niikuni, Koji Okamoto, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, MD PhD, Ryo Ichinohasama, MD PhD, Yukio Nakamura, MD, PhD, Tohru Tanaka, PhD, Hideo Harigae, MD PhD

Blood (2014) 124 (21): 215.

https://doi.org/10.1182/blood.V124.21.215.215

Published: 2014

Journal Articles

Interleukin-6 Reduces Erythroid Development and Mitochondrial Membrane Potential In Human Erythroleukemic Cells

Bryan J. McCranor, PhD, MinJung Kim, PhD, Nicole M Cruz, Qian-Li Xue, PhD, Alan E. Berger, PhD, Jeremy D. Walston, M.D., Curt I. Civin, M.D., Cindy N. Roy, PhD

Blood (2013) 122 (21): 3420.

https://doi.org/10.1182/blood.V122.21.3420.3420

Published: 2013

Journal Articles

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Jason N Berman, MD, Pedro Fernandez-Murray, PhD, Gheyath Nasrallah, PhD, Noelia Dufay, PhD, Conrad V Fernandez, FRCPC, BSc, MD, Ameer Jarrar, MSc, Andrew J Coombs, BSc(Hon), Christopher McMaster, PhD

Blood (2012) 120 (21): 2087.

https://doi.org/10.1182/blood.V120.21.2087.2087

Published: 2012

NARROW

Molecular Characterization and Novel Therapeutic Strategy for X-Linked Sideroblastic Anemia Associated with ALAS2 Missense Variants

An Orchestrated Balance between Mitochondria Biogenesis, Iron-Sulfur Cluster Synthesis and Cellular Iron Acquisition

AMPK Regulates the Expression of the Fe-S Cluster Assembly Enzyme (ISCU) and ALAS2, Modulating Cellular Iron Metabolism and Increasing Hemoglobin Synthesis

Explore: A Prospective, Multinational Natural History Study of Patients with Acute Hepatic Porphyrias (AHP) with Recurrent Attacks

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

Endothelial Cell-Selective Adhesion Molecule (ESAM) Plays Important Roles in the Adult-Type Hemoglobin Synthesis during Fetal Erythropoiesis

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Role of Heme in the Regulation of Transferrin Receptor Expression in Erythroid Cells

The Role of TCA Cycle Compounds in Erythroid Heme Synthesis and Its Regulation During an Inflammatory Response

Mutation of a GATA1 Binding Site in ALAS2 Intron 1 Arrests Murine Erythroid Development In Vivo

Interim Data from a Randomized, Placebo Controlled, Phase 1 Study of Aln-AS1, an Investigational RNAi Therapeutic for the Treatment of Acute Hepatic Porphyria

The Interplay of GATA1 with Heme Regulates an Erythroid Cell's Differentiation

Endothelial Cell-Selective Adhesion Molecule (ESAM) Is Required for the Ontogeny of Definitive Hematopoietic System in Mice

Generation of Induced Pluripotent Stem Cell-Derived Erythroblasts from a Patient with X-Linked Sideroblastic Anemia

Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation

Mechanism Governing Heme Synthesis Reveals a GATA Factor-Heme Circuit That Controls Differentiation

Transcriptional Induction of Transferrin Receptors By Heme in Erythroid Cells

Exploring the Potential Usefulness of 5-Aminolevulinic Acid for X-Linked Sideroblastic Anemia

Interleukin-6 Reduces Erythroid Development and Mitochondrial Membrane Potential In Human Erythroleukemic Cells

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only