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Journal Articles

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Sophia Adamia, PhD, Daisuke Ogiya, MD PhD, Ivane Abiatari, MD, Sigitas J Verselis, PhD, Michael P. Chu, David M. Dorfman, MD PhD, Linda M. Pilarski, PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3079.

https://doi.org/10.1182/blood-2019-131243

Published: 2019

Journal Articles

Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis

Lihui Zhuang, PhD MSc, BSc, Richard Darley, PhD, Oliver G. Ottmann, MD, Joanna Zabkiewicz, PhD, Caroline Alvares, MBBS, PhD

Blood (2018) 132 (Supplement 1): 2776.

https://doi.org/10.1182/blood-2018-99-113811

Published: 2018

Journal Articles

Extracellular Vesicle microRNAs from Acute Myeloid Leukemia Are Involved in the Regulation of Adherence Junction in Bone Marrow Microenvironment.

Blood (2016) 128 (22): 2863.

https://doi.org/10.1182/blood.V128.22.2863.2863

Published: 2016

Journal Articles

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

John D Shaughnessy, Jr., PhD, Samir Parekh, MD, Hearn Jay Cho, MD PhD, Alessandro Lagana, PhD, Ajai Chari, MD, Ryan van Laar, PhD, Sundar Jagannath, MD, Bart Barlogie, MD PhD

Blood (2016) 128 (22): 4450.

https://doi.org/10.1182/blood.V128.22.4450.4450

Published: 2016

Journal Articles

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Yongzhi Qiu, PhD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Caroline Hansen, BS, Clinton H. Joiner, MD PhD, Solomon Fiifi Ofori-Acquah, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 240.

https://doi.org/10.1182/blood.V126.23.240.240

Published: 2015

Journal Articles

Kindlin-2 Maintains Vascular Barrier Integrity By Stabilizing Endothelial Adherens Junctions

Elzbieta Pluskota, PhD, Dorota Szpak, B.S., Katarzyna Bialkowska, PhD, Kamila Bledzka, PhD, Edward F. Plow, PhD

Blood (2015) 126 (23): 3452.

https://doi.org/10.1182/blood.V126.23.3452.3452

Published: 2015

Journal Articles

Regulation of Stimulated and Basal Release of Weibel-Palade Bodies By Syntaxin-3 Containing SNARE-Complexes

Dorothee Van Breevoort, PhD, Maryam Wahedi, Maaike Schillemans, Tom Carter, PhD, Stephan Huveneers, PhD, Maartje van den Biggelaar, PhD, J.J. Voorberg, PhD, Ruben Bierings, PhD

Blood (2014) 124 (21): 1440.

https://doi.org/10.1182/blood.V124.21.1440.1440

Published: 2014

Journal Articles

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

Hogune Im, PhD, Varsha Rao, PhD, Kunju Joshi Sridhar, PhD, Rui Chen, PhD, George Mias, PhD, Yan Zhang, MD, Li Xiao, MD, Michael P Snyder, PhD, Peter L. Greenberg, MD

Blood (2014) 124 (21): 1894.

https://doi.org/10.1182/blood.V124.21.1894.1894

Published: 2014

Journal Articles

Exome Sequencing Identifies Recurring FLT3 N676K Mutations in Core Binding Factor Leukemia

Sabrina Opatz, Harald Polzer, Tobias Herold, MD, Nikola P Konstandin, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Karl Peter Hopfner, PhD, Purvi M. Kakadia, PhD, Stephanie Schneider, PhD, Annika Dufour, PhD, Jan Braess, MD, Michael Heuser, MD, Wolfgang Hiddemann, MD, PhD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Philipp A Greif, MD

Blood (2012) 120 (21): 404.

https://doi.org/10.1182/blood.V120.21.404.404

Published: 2012

Journal Articles

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting

Malika Oubaha, Michelle I. Lin, Yoran Margaron, Dominic Filion, Emily N. Price, Leonard I. Zon, Jean-François Côté, Jean-Philippe Gratton

Blood (2012) 120 (16): 3371–3381.

https://doi.org/10.1182/blood-2012-03-419721

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

Erming Tian, PhD, Saad Usmani, MD, FACP, Yiming Zhou, PhD, Bart Barlogie, MD, Ph.D, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 3932.

https://doi.org/10.1182/blood.V118.21.3932.3932

Published: 2011

Journal Articles

RIAM and RapL, Two Structurally Divergent Rap1 Effectors, Have Distinct Signaling and Functional Roles in TCR-Mediated Activation

Nikolaos Patsoukis, PhD, Esther M Lafuente, PhD, Vassiliki A Boussiotis, MD, PhD

Blood (2011) 118 (21): 1118.

https://doi.org/10.1182/blood.V118.21.1118.1118

Published: 2011

Journal Articles

Origin of Hematopoietic Stem Cells

Hanna Mikkola, MD, PhD

Blood (2010) 116 (21): SCI-40.

https://doi.org/10.1182/blood.V116.21.SCI-40.SCI-40

Published: 2010

Journal Articles

Alpha-Catenin, ARHGAP21 and β-Catenin Are Abnormally Expressed in Bone Marrow Cells From Patients with Myelodysplatic Syndromes and Are a Possible Target for Decitabine Treatment.

Karin Spat Barcellos, PhD, in, Molecular, Biology, Sheila Maria Winnischofer, PhD, Mariana Lazarini, Master, Degree, Doctorate, Stude, Adriana Silva Santos Duarte, PhD, Carolina Louzao Bigarella, PhD, Fabiola Traina, MD, PhD, Fernando Ferreira Costa, Ph.D., M.D., Sara T.O Saad, M.D., Ph.D.

Blood (2009) 114 (22): 1778.

https://doi.org/10.1182/blood.V114.22.1778.1778

Published: 2009

Journal Articles

Cellular Interaction Between Human Mesenchymal Stem Cells and Hematopoietic Stem Cells in 2D- and 3D-Culture-Systems.

Patrick Wuchter, MD, Rainer Saffrich, PhD, Annette Ludwig, Mario Schubert, MD, Volker Eckstein, PhD, Anthony D. Ho, MD, PhD

Blood (2009) 114 (22): 1442.

https://doi.org/10.1182/blood.V114.22.1442.1442

Published: 2009

Journal Articles

RIAM and RapL Regulate Distinct Signaling Events and Functional Outcomes Upon TCR-Mediated Activation.

Nikolaos Patsoukis, PhD, Esther M Lafuente, PhD, Vassiliki A Boussiotis, MD, PhD

Blood (2009) 114 (22): 3683.

https://doi.org/10.1182/blood.V114.22.3683.3683

Published: 2009

Journal Articles

Blood Flow Is Required for the Release of Hematopoietic Stem- and Progenitor Cells From Hemogenic Endothelium in the Placenta.

Katrin E Rhodes, Ben Van Handel, Michele Wang, Yanling Wang, Akanksha Chhabra, Hanna Mikkola, MD, PhD

Blood (2009) 114 (22): 698.

https://doi.org/10.1182/blood.V114.22.698.698

Published: 2009

Journal Articles

Vascular Endothelial-Cadherin Targeted Alpha-Particle Mediated Vascular Killing and Remodeling Augments Subsequent Chemotherapeutic Efficacy.

Freddy E Escorcia, Erik Henke, PhD, Michael R. McDevitt, PhD, Carlos Villa, Peter Smith-Jones, PhD, Ronald Blasberg, MD, Robert Benezra, David A. Scheinberg, MD, PhD

Blood (2009) 114 (22): 3054.

https://doi.org/10.1182/blood.V114.22.3054.3054

Published: 2009

Journal Articles

A Specific Gene Expression Signature Affecting the Beta-Catenin and Notch Signaling Pathways and the Downregulation of MALAT1 Prove Acute Myeloid Leukemia with Limited Differentiation (AML-LD) as a Distinct Entity with NPM1 Mutation.

Wolfgang Kern, MD, Vera Grossmann, MA, Alexander Kohlmann, PhD, Susanne Schnittger, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD

Blood (2009) 114 (22): 164.

https://doi.org/10.1182/blood.V114.22.164.164

Published: 2009

Journal Articles

Human Hematopoietic Stem Cells and Leukemic Cells Form Cadherin-Catenin Based Junctional Complexes with Mesenchymal Stromal Cells

Patrick Wuchter, M.D., Rainer Saffrich, Ph.D., Wolfgang Wagner, Ph.D., M.D., Frederik Wein, Ph.D., Mario Stephan Schubert, M.D., Volker Eckstein, Ph.D., Anthony D. Ho, M.D., Ph.D.

Blood (2008) 112 (11): 1367.

https://doi.org/10.1182/blood.V112.11.1367.1367

Published: 2008

NARROW

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis

Extracellular Vesicle microRNAs from Acute Myeloid Leukemia Are Involved in the Regulation of Adherence Junction in Bone Marrow Microenvironment.

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Kindlin-2 Maintains Vascular Barrier Integrity By Stabilizing Endothelial Adherens Junctions

Regulation of Stimulated and Basal Release of Weibel-Palade Bodies By Syntaxin-3 Containing SNARE-Complexes

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

Exome Sequencing Identifies Recurring FLT3 N676K Mutations in Core Binding Factor Leukemia

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

RIAM and RapL, Two Structurally Divergent Rap1 Effectors, Have Distinct Signaling and Functional Roles in TCR-Mediated Activation

Origin of Hematopoietic Stem Cells

Alpha-Catenin, ARHGAP21 and β-Catenin Are Abnormally Expressed in Bone Marrow Cells From Patients with Myelodysplatic Syndromes and Are a Possible Target for Decitabine Treatment.

Cellular Interaction Between Human Mesenchymal Stem Cells and Hematopoietic Stem Cells in 2D- and 3D-Culture-Systems.

RIAM and RapL Regulate Distinct Signaling Events and Functional Outcomes Upon TCR-Mediated Activation.

Blood Flow Is Required for the Release of Hematopoietic Stem- and Progenitor Cells From Hemogenic Endothelium in the Placenta.

Vascular Endothelial-Cadherin Targeted Alpha-Particle Mediated Vascular Killing and Remodeling Augments Subsequent Chemotherapeutic Efficacy.

A Specific Gene Expression Signature Affecting the Beta-Catenin and Notch Signaling Pathways and the Downregulation of MALAT1 Prove Acute Myeloid Leukemia with Limited Differentiation (AML-LD) as a Distinct Entity with NPM1 Mutation.

Human Hematopoietic Stem Cells and Leukemic Cells Form Cadherin-Catenin Based Junctional Complexes with Mesenchymal Stromal Cells

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American Society of Hematology

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American Society of Hematology

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