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Journal Articles

Acadesine Elicits a Rapid Epigenetic Reprograming of Immediate Early Genes through the Protein Kinase D1 Pathway in Acute Lymphoblastic Leukemia Cells Undergoing Energy/Metabolic Stress

Guangyan C Sun, PhD, Anna C Shvab, Bin C Li, PhD, Felipe C Beckedorff, Guy Jacques Leclerc, PhD, Ramin Shiekhattar, PhD, Julio C Barredo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1321.
https://doi.org/10.1182/blood-2018-99-112678
Published: 2018
Journal Articles

8-Chloro-Adenosine Inhibits Molecular Poor-Risk Acute Myeloid Leukemia (AML) and Leukemic Stem Cells (LSC) Growth and Synergizes with the BCL-2 Inhibitor Venetoclax (ABT-199)

Ralf Buettner, PhD, Ching-Cheng Chen, PhD, Bijender Kumar, PhD, Corey Morales, BA, BS, Lisa S Chen, PhD, Krister Wennerberg, PhD, Ryan Thompson, MS, Tea Pemovska, MSc, Ling Li, PhD, Bin Zhang, PhD, Claudia Kowolik, PhD, Mika Kontro, MD, Calum Leitch, MD, David Horne, PhD, Joycelynne Palmer, PhD, Varsha Gandhi, PhD, Guido Marcucci, MD, Vinod Pullarkat, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 2758.
https://doi.org/10.1182/blood.V128.22.2758.2758
Published: 2016
Journal Articles

Exquisite Sensitivity of Plasma Cell Malignancies to a Novel Nucleoside Analog Is Mediated By Overexpressed Adenosine Kinase

Utthara Nayar, Jouliana Sadek, Jonathan B Reichel, David Bunn, Denise Hernandez-Hopkins, Peter Barelli, Michelle Sahai, Jennifer Totonchy, Sei Shizuko, Robert Shoemaker, David Warren, Olivier Elemento, Kenneth Kaye, Ethel Cesarman
Journal: Blood
Blood (2015) 126 (23): 1812.
https://doi.org/10.1182/blood.V126.23.1812.1812
Published: 2015
Journal Articles

8-Chloro-Adenosine Inhibits Molecular Poor-Risk Acute Myeloid Leukemia (AML) and Leukemic Stem Cells (LSC) Growth Via Novel RNA- and ATP-Directed Mechanisms: A Novel Therapeutic Approach for AML

Ralf Buettner, PhD, Ching-Cheng Chen, PhD, Bijender Kumar, PhD, Lisa S Chen, PhD, Krister Wennerberg, PhD, Ryan Thompson, MS, Tea Pemovska, MSc, Ling Li, PhD, Varsha Gandhi, PhD, Guido Marcucci, MD, Vinod Pullarkat, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2015) 126 (23): 792.
https://doi.org/10.1182/blood.V126.23.792.792
Published: 2015
Journal Articles

A New Form Of Therapeutic Resistance: Drug Glucuronidation Regulated By The Sonic Hedgehog Factor Gli1

Hiba A Zahreddine, Biljana Culjkovic-Kraljacic, PhD, Sarit Assouline, MD, Abdellatif Amri, Patrick Gendron, M.Sc., Andrea A. Romeo, PhD, Stephen Morris, PhD, James Jaquith, PhD, Gregory Cormack, Eftihia Cocolakis, PhD, Julie Bergeron, MD, Leandro Cerchietti, MD, Brian Leber, MD, Wilson H. Miller, Jr., MD, PhD, Katherine LB. Borden, PhD
Journal: Blood
Blood (2013) 122 (21): 821.
https://doi.org/10.1182/blood.V122.21.821.821
Published: 2013
Journal Articles

HIF-1–dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak

Julio C. Morote-Garcia, Peter Rosenberger, Johannes Kuhlicke, Holger K. Eltzschig
Journal: Blood
Blood (2008) 111 (12): 5571–5580.
https://doi.org/10.1182/blood-2007-11-126763
Published: 2008
Journal Articles

Myeloma Cell Proliferation Is Inhibitied by the Activation of Adenosine Monophosphate Activated Protein Kinase (AMPK).

Philipp Baumann, Sonja Mandl-Weber, Bertold Emmerich, Christian Straka, Daniel Franke, Ralf Schmidmaier
Journal: Blood
Blood (2006) 108 (11): 5045.
https://doi.org/10.1182/blood.V108.11.5045.5045
Published: 2006