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Journal Articles

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

Markus Spindler, Judith M. M. van Eeuwijk, Yvonne Schurr, Paquita Nurden, Bernhard Nieswandt, David Stegner, Annegret Reinhold, Markus Bender

Blood (2018) 132 (6): 635–646.

https://doi.org/10.1182/blood-2018-01-829259

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Impact of Kindlin-3 in NK Cell-Mediated Anti-Tumor Cytotoxicity and Inflammatory Cytokine Production

Nathan J. Schloemer, MD, Alex M Abel, MS, Monica S Thakar, MD, Yan-Qing Ma, PhD, Subramaniam Malarkannan, PhD

Blood (2015) 126 (23): 208.

https://doi.org/10.1182/blood.V126.23.208.208

Published: 2015

Journal Articles

ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding

Ana Kasirer-Friede, Jian Kang, Bryan Kahner, Feng Ye, Mark H. Ginsberg, Sanford J. Shattil

Blood (2014) 123 (20): 3156–3165.

https://doi.org/10.1182/blood-2013-08-520627

Published: 2014

Includes: Supplemental data

Journal Articles

Tyrosine Phosphatase SHP-1 Acts As a Key Regulator Of Alloresponses In Primary Murine T Cells

Christian Kardinal, Ph.D., Jessica Herbst, Ulf Diekmann, M.Sc., Martin G. Sauer, MD

Blood (2013) 122 (21): 3489.

https://doi.org/10.1182/blood.V122.21.3489.3489

Published: 2013

Journal Articles

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

Rebecca M. May, Mariko Okumura, Chin-Jung Hsu, Hamid Bassiri, Enjun Yang, Gregory Rak, Emily M. Mace, Naomi H. Philip, Weiguo Zhang, Tobias Baumgart, Jordan S. Orange, Kim E. Nichols, Taku Kambayashi

Blood (2013) 121 (16): 3135–3146.

https://doi.org/10.1182/blood-2012-12-474361

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

A detailed proteomic analysis of rhodocytin-activated platelets reveals novel clues on the CLEC-2 signalosome: implications for CLEC-2 signaling regulation

Andrés F. Parguiña, Jana Alonso, Isaac Rosa, Paula Vélez, María J. González-López, Esteban Guitián, Johannes A. Eble, María I. Loza, Ángel García

Blood (2012) 120 (26): e117–e126.

https://doi.org/10.1182/blood-2012-09-456004

Published: 2012

Includes: Supplemental data

Journal Articles

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

Stefanie Kliche, Tim Worbs, Xiaoqian Wang, Janine Degen, Irene Patzak, Bernhard Meineke, Mauro Togni, Markus Moser, Annegret Reinhold, Friedemann Kiefer, Christian Freund, Reinhold Förster, Burkhart Schraven

Blood (2012) 119 (3): 777–785.

https://doi.org/10.1182/blood-2011-06-362269

Published: 2012

Includes: Supplemental data

Journal Articles

ADAPtation of Platelet Integrin αIIbβ3 to Inside-Out Activation Signals

Ana Kasirer-Friede, PhD, Jian Kang, PhD, Bryan N Kahner, PhD, Sanford J. Shattil, MD

Blood (2011) 118 (21): 188.

https://doi.org/10.1182/blood.V118.21.188.188

Published: 2011

Journal Articles

Role for ADAP in shear flow–induced platelet mechanotransduction

Ana Kasirer-Friede, Zaverio M. Ruggeri, Sanford J. Shattil

Blood (2010) 115 (11): 2274–2282.

https://doi.org/10.1182/blood-2009-08-238238

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

If Virchow were to meet Newton

Michael H. Kroll

Blood (2010) 115 (11): 2123–2124.

https://doi.org/10.1182/blood-2009-12-260505

Published: 2010

Journal Articles

RIAM Regulate Spatio-Temporal Distribution of PLC-γ1 and Calcium Mobilization during T Cell Activation

Nikolaos Patsoukis, PhD, Esther M Lafuente, PhD, Paul Meraner, Lequn Li, MD, PhD, David Dombkowski, Anjana Rao, Vassiliki Boussiotis, MD, PhD

Blood (2008) 112 (11): 673.

https://doi.org/10.1182/blood.V112.11.673.673

Published: 2008

Journal Articles

The Cytokine Signal Inhibitor Lnk Promotes αIIbβ3 Integrin Outside-In Signaling through β3 Tyrosine Phosphorylation in Platelets.

Koji Eto, MD, PhD, Hitoshi Takizawa, Ph.D., Satoshi Takaki, M.D., Ph.D., Hidekazu Nishikii, M.D., Atsushi Oda, M.D., Ph.D., Hiromitsu Nakauchi, M.D., Ph.D.

Blood (2007) 110 (11): 3651.

https://doi.org/10.1182/blood.V110.11.3651.3651

Published: 2007

Journal Articles

ADAP is required for normal αIIbβ3 activation by VWF/GP Ib-IX-V and other agonists

Ana Kasirer-Friede, Barry Moran, Jennifer Nagrampa-Orje, Ken Swanson, Zaverio M. Ruggeri, Burkhart Schraven, Benjamin G. Neel, Gary Koretzky, Sanford J. Shattil

Blood (2006) 109 (3): 1018–1025.

https://doi.org/10.1182/blood-2006-05-022301

Published: 2006

Journal Articles

The actin cloud induced by LFA-1–mediated outside-in signals lowers the threshold for T-cell activation

Jun-ichiro Suzuki, Sho Yamasaki, Jennifer Wu, Gary A. Koretzky, Takashi Saito

Blood (2006) 109 (1): 168–175.

https://doi.org/10.1182/blood-2005-12-020164

Published: 2006

Includes: Supplemental data

Journal Articles

Inside-Out Signaling through ADAP Is Required for VWF-GPIb-IX-V Mediated Integrin AIibb3 Activation.

Ana Kasirer-Friede, PhD, Barry P. Moran, M.Sc, Jennifer Nagrampa-Orje, B.Sc, Ken Swanson, PhD, Burkhart Schraven, PhD, Ben Neel5, MD, Zaverio M. Ruggeri, MD, Sanford J. Shattil, MD

Blood (2005) 106 (11): 379.

https://doi.org/10.1182/blood.V106.11.379.379

Published: 2005

Journal Articles

Signaling through GP Ib-IX-V activates αIIbβ3 independently of other receptors

Ana Kasirer-Friede, Maria Rita Cozzi, Mario Mazzucato, Luigi De Marco, Zaverio M. Ruggeri, Sanford J. Shattil

Blood (2004) 103 (9): 3403–3411.

https://doi.org/10.1182/blood-2003-10-3664

Published: 2004

NARROW

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

Impact of Kindlin-3 in NK Cell-Mediated Anti-Tumor Cytotoxicity and Inflammatory Cytokine Production

ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding

Tyrosine Phosphatase SHP-1 Acts As a Key Regulator Of Alloresponses In Primary Murine T Cells

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

A detailed proteomic analysis of rhodocytin-activated platelets reveals novel clues on the CLEC-2 signalosome: implications for CLEC-2 signaling regulation

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

ADAPtation of Platelet Integrin αIIbβ3 to Inside-Out Activation Signals

Role for ADAP in shear flow–induced platelet mechanotransduction

If Virchow were to meet Newton

RIAM Regulate Spatio-Temporal Distribution of PLC-γ1 and Calcium Mobilization during T Cell Activation

The Cytokine Signal Inhibitor Lnk Promotes αIIbβ3 Integrin Outside-In Signaling through β3 Tyrosine Phosphorylation in Platelets.

ADAP is required for normal αIIbβ3 activation by VWF/GP Ib-IX-V and other agonists

The actin cloud induced by LFA-1–mediated outside-in signals lowers the threshold for T-cell activation

Inside-Out Signaling through ADAP Is Required for VWF-GPIb-IX-V Mediated Integrin AIibb3 Activation.

Signaling through GP Ib-IX-V activates αIIbβ3 independently of other receptors

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American Society of Hematology

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ASH Publications

American Society of Hematology

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