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Journal Articles

α-Ketoglutarate promotes amino acid depletion and suppresses B-cell lymphoma growth and development

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Carine Jaafar, Purushoth Ethiraj, Zhijun Qiu, An-Ping Lin, Pedro Simonis Seabra Martins Ferrari, Ricardo Aguiar
Journal: Blood
Blood blood.2024028069.
https://doi.org/10.1182/blood.2024028069
Published: 2025
Includes: Supplemental data
Journal Articles

Perturbation of Intermediary Metabolism Inhibits Glycolysis, Oxidative Phosphorylation, Amino Acid Synthesis and Prevents Lymphoma Development in Mice

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Purushoth Ethiraj, Carine Jaafar, An-Ping Lin, Zhijun Qiu, Ricardo Aguiar
Journal: Blood
Blood (2022) 140 (Supplement 1): 1694–1695.
https://doi.org/10.1182/blood-2022-160395
Published: 2022
Journal Articles

Alpha-Ketoglutarate Suppresses MYC and mTORC1 and Displays Anti-Lymphoma Activity

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Carine Jaafar, Purushoth Ethiraj, Zhijun Qiu, An-Ping Lin, Ricardo Aguiar
Journal: Blood
Blood (2022) 140 (Supplement 1): 2046–2047.
https://doi.org/10.1182/blood-2022-160374
Published: 2022
Journal Articles

Cyclic-AMP Is an Actionable Novel Regulator of PD-L1 Expression in Untransformed Lymphocytes and Diffuse Large B Cell Lymphomas

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Binu Sasi, PhD, Zhijun Qiu, PhD, Shoulei Jiang, PhD, An-Ping Lin, MD, Ricardo Aguiar, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3962.
https://doi.org/10.1182/blood-2019-123155
Published: 2019
Journal Articles

A MYC Driven and Metabolite Executed Axis Controls the Subcellular Localization and Activity of TET DNA Hydroxylases and RNA Demethylases in B Cell Lymphomas

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Zhijun Qiu, PhD, An-Ping Lin, MD, Shoulei Jiang, PhD, Binu Sasi, PhD, Patricia Dahia, MD PhD, Siyuan Zheng, PhD, Ricardo Aguiar, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 114.
https://doi.org/10.1182/blood-2019-123101
Published: 2019
Journal Articles

Mitochondrial Metabolism and RNA Methylation in DLBCL

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Sara Elkashef, PhD, An-Ping Lin, MD, Lilly Chiou, Jamie Myers, MSc, ZhiJun Qiu, PhD, Ricardo C.T. Aguiar, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2732.
https://doi.org/10.1182/blood.V130.Suppl_1.2732.2732
Published: 2017