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Zachary Hutchins
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Journal Articles

Targeting the methylome in T-LGL leukemia: Pre-clinical analysis and Results of a Phase I trial with oral 5-azacytidine

Free
Jonathan Brammer, Zachary Braunstein, Patrick Stevens, Zachary Hutchins, Giulia Calabretto, Soprina Guarneri, Eric McLaughlin, Amy Boles, John Reneau, Walter Hanel, Enrica Marchi, Maciej Pietrzak, Anjali Mishra
Journal: Blood
Blood (2025) 146 (Supplement 1): 890.
https://doi.org/10.1182/blood-2025-890
Published: 2025
Journal Articles

Functional analysis of STAT3 activating mutations in LGL leukemia reveals epigenetic reprograming and therapeutic vulnerabilities.

Free
Zachary Hutchins, Robyn Keller, Molly Halloran, Colleen Isabelle, Kathleen McConnell, Amy Boles, Maria Altemus, Rachel Burzinski, Giulia Calabretto, Nitin Chakravarti, Jonathan Brammer, Anjali Mishra
Journal: Blood
Blood (2025) 146 (Supplement 1): 5035.
https://doi.org/10.1182/blood-2025-5035
Published: 2025
Journal Articles

Activating STAT3 Mutations Drive CD38 Expression in T-Large Granular Lymphocytic Leukemia

Free
Giulia Calabretto, Elena Buson, Zachary Hutchins, Colleen Isabelle, Sydnee Scozzafava, Valentina Trimarco, Barbara Mariotti, Rachel Burzinski, Amy Boles, Elisa Rampazzo, Antonella Teramo, Sabrina Manni, Monica Facco, Gregorio Barilà, Flavia Bazzoni, Gianpietro Semenzato, Livio Trentin, Jonathan E. Brammer, Renato Zambello, Anjali Mishra
Journal: Blood
Blood (2024) 144 (Supplement 1): 4132.
https://doi.org/10.1182/blood-2024-210469
Published: 2024