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Journal Articles

Mitochondrial Iron Transport Via MFRN1 Is Required for Erythroid Cell Cycle Progression Even Under Iron-Replete Conditions Sufficient for Hemoglobinization

Mark Perfetto, Aidan Danoff, Muhammad Ishfaq, Aiden Mohideen, Meilin Chen, Amber Stratman, Satoshi Okawa, Yvette Y. Yien
Journal: Blood
Blood (2024) 144 (Supplement 1): 2469.
https://doi.org/10.1182/blood-2024-203047
Published: 2024
Journal Articles

What does the FOX(O) say? High iron: hepcidin!

Yvette Y. Yien
Journal: Blood
Blood (2024) 144 (12): 1243–1245.
https://doi.org/10.1182/blood.2024025595
Published: 2024
Journal Articles

The Clpx G298D Mutation in Clpx-EPP Reveals That Clpx Regulates the Mitochondria Enzymes in Erythroid Heme Synthesis Via Distinct Mechanisms

Yvette Y. Yien, Samantha Gillis, Mark Perfetto, Hector Bergonia
Journal: Blood
Blood (2023) 142 (Supplement 1): 2469.
https://doi.org/10.1182/blood-2023-187918
Published: 2023
Journal Articles

Regulation of Iron Transport Is Required for Terminal Erythroid Differentiation Even Under Iron-Replete Conditions Sufficient for Hemoglobinization

Yvette Y. Yien, Meilin Chen, Aidan Danoff, Amber Stratman
Journal: Blood
Blood (2022) 140 (Supplement 1): 5353–5354.
https://doi.org/10.1182/blood-2022-170277
Published: 2022
Journal Articles

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Catherine Rondelli, Aiden Danoff, Hector Bergonia, Samantha Gillis, Julia Free, John D. Phillips, PhD, Yvette Y Yien, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 427.
https://doi.org/10.1182/blood-2019-132039
Published: 2019
Journal Articles

Target of Erythropoietin, Fam210b , Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity

Yvette Y Yien, PhD, Jiahai Shi, PhD, Caiyong Chen, PhD, Jesmine Cheung, Anthony Grillo, PhD, Rishna Shrestha, Liangtao Li, PhD, Xuedi Zhang, Martin Daniel Kafina, MS, BA, Paul D. Kingsley, PhD, Matthew King, Julien Ablain, PhD, Leonard I. Zon, MD, James Palis, MD, Martin Burke, Daniel E. Bauer, MD PhD, Stuart H. Orkin, MD, Carla Koehler, PhD, John D. Phillips, PhD, Jerry Kaplan, PhD, Diane Ward, PhD, Harvey Lodish, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 849.
https://doi.org/10.1182/blood-2018-99-120299
Published: 2018
Journal Articles

A Dominant Mutation in Mitochondrial Unfoldase CLPX Results in Erythropoietic Protoporphyria

Yvette Y Yien, PhD, Gael Nicolas, PhD, Lisa van der Vorm, Laurent Gouya, MD PhD, Hector Begonia, Martin Kafina, Jean-Charles Deybach, MD PhD, Tania Baker, PhD, Julia Kardon, PhD, John D. Phillips, PhD, Hervé Puy, MD PhD, Barry H. Paw, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 77.
https://doi.org/10.1182/blood.V128.22.77.77
Published: 2016
Journal Articles

Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation

Yvette Y Yien, PhD, Caiyong Chen, PhD, Jiahai Shi, PhD, Liangtao Li, PhD, Daniel E. Bauer, MD, PhD, Nicholas Huston, Paul D. Kingsley, PhD, Julien Ablain, Leonard I Zon, MD, James Palis, MD, Stuart H. Orkin, MD, Jerry Kaplan, PhD, John D Phillips, PhD, Harvey F. Lodish, PhD, Barry Paw, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 405.
https://doi.org/10.1182/blood.V126.23.405.405
Published: 2015
Journal Articles

Erythroid Cells Adapt to L-Leucine Scarcity By Reducing Hemoglobin Production Via the mTORC1/4E-BP Pathway

Jacky Chung, PhD, Daniel E. Bauer, MD, PhD, Alireza Ghamari, PhD, Christopher P. Nizzi, M.Sc., Kathryn M. Deck, PhD, Paul D. Kingsley, PhD, Yvette Y. Yien, PhD, Nicholas C. Huston, B.A., Caiyong Chen, PhD, Johannes G. Wittig, B.Sc., James Palis, MD, Stuart H. Orkin, MD, Harvey F. Lodish, PhD, Richard S. Eisenstein, PhD, Alan B. Cantor, Barry H. Paw, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2660.
https://doi.org/10.1182/blood.V124.21.2660.2660
Published: 2014
Journal Articles

Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism

Barry H. Paw, M.D., Ph.D., Yvette Y. Yien, Ph.D., Raymond F Robledo, Ph.D., Iman J. Schultz, Ph.D., Naoko Takahashi-Makise, Ph.D., John Philllips, Ph.D., Non Miyata, Ph.D., Babette Gwynn, M.S., Tamara A. Dailey, Ph.D., Eric Pierce, B.S., Gordon J. Hildick-Smith, B.A., Jeffrey D. Cooney, B.S., M.S., Wen Chen, Ph.D., Dhvanit I. Shah, Ph.D., Shilpa M Hattangadi, M.D., Paul D Kingsley, Ph.D., James Palis, M.D., Alan B. Cantor, M.D., Ph.D., Carla M. Koehler, Ph.D., Harvey F. Lodish, Ph.D., Jerry Kaplan, Ph.D., Harry A. Dailey, Ph.D., Diane McVey Ward, Ph.D., Luanne L. Peters, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 427.
https://doi.org/10.1182/blood.V122.21.427.427
Published: 2013
Journal Articles

SNX3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation in Developing Erythrocytes*

Caiyong Chen, Ph.D., Daniel Garcia Santos, Ph.D., Yuichi Ishikawa, Ph.D., Alexandra Seguin, Liangtao Li, Ph.D., Katherine H. Fegan, MS, Gordon J. Hildick-Smith, Jeffrey D. Cooney, MA, Wen Chen, Ph.D., Matthew J. King, Iman J. Schultz, Ph.D., Yvette Y. Yien, Ph.D., Arthur J. Dalton, Paul D Kingsley, Ph.D., James Palis, MD, Shilpa Hattangadi, MD, Harvey F. Lodish, PhD, Diane M. Ward, Ph.D., Jerry Kaplan, Ph.D., Takahiro Maeda, M.D., Ph.D., Prem Ponka, MD, PhD, Barry H. Paw, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 607.
https://doi.org/10.1182/blood.V120.21.607.607
Published: 2012