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Journal Articles

Genome-Wide Association Study Identifies Variation in ABO As Risk Factor for Platelet Reactivity in Heparin-Induced Thrombocytopenia

Jason B Giles, Jérôme Rollin, PhD, Christian M Shaffer, Heidi E Steiner, Yukihide Momozawa, DVM,PhD, Ian Stanaway, PhD, Taisei Mushiroda, Claire Pouplard, PharmD, PhD, Nancy Heddle, MSc, Michiaki Kubo, MDPhD, Elizabeth Phillips, MD, Theodore E. Warkentin, MD, Yves Gruel, MD PhD, Andreas Greinacher, MD, Dan Roden, MD, Jason Karnes, PhDPharmD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-139651

Published: 2020

Journal Articles

Is There an Alternative to Serotonin Release Assay for the Diagnosis of Heparin Induced Thrombocytopenia (HIT)? Evaluation of 5 Other Functional Methods Using 5B9 a Monoclonal IgG That Mimics HIT Human Antibodies

Eve-Anne Guéry, PharmD, Caroline Vayne, PharmD, Cloé Derray, Joévin Besombes, Wayne Corentin Lambert, Jérôme Rollin, PhD, Yves Gruel, MD PhD, Claire Pouplard, PharmD, PhD

Blood (2018) 132 (Supplement 1): 3742.

https://doi.org/10.1182/blood-2018-99-115011

Published: 2018

Journal Articles

Cleavage of Anti-PF4/H IgG Antibodies By Ides, and Potential Benefit in the Treatment of Heparin-Induced Thrombocytopenia

Claire Kizlik-Masson, Quentin Deveuve, Yuhang Zhou, MD PhD, Caroline Vayne, PharmD, Gilles Thibault, PharmD, PhD, Steven Edward McKenzie, MD PhD, Claire Pouplard, PharmD, PhD, Stéphane Loyau, Jérôme Rollin, PhD, Yves Gruel, MD PhD

Blood (2018) 132 (Supplement 1): 518.

https://doi.org/10.1182/blood-2018-99-114450

Published: 2018

Journal Articles

Frequency of Anti-PF4/Heparin Antibodies in Patients Treated with Extra-Corporeal Membrane Oxygenation and Detection By Sensitized Serotonin Release Assay of Pathogenic Heparin-Induced Thrombocytopenia Antibodies

Caroline Vayne, PharmD, Marc-Antoine May, MD, Thierry Bourguignon, MD PhD, Eric Lemoine, MD, Eve-Anne Guéry, PharmD, Jérôme Rollin, PhD, Yves Gruel, MD PhD, Claire Pouplard, PharmD, PhD

Blood (2018) 132 (Supplement 1): 1143.

https://doi.org/10.1182/blood-2018-99-114571

Published: 2018

Journal Articles

Gastrointestinal Bleeding and Angiodysplasia in Von Willebrand Disease: Results from the Ongoing French HRQoL Study: Wish-Qol

Annie Borel-Derlon, MD PhD, Dominique Desprez, MD, Fabienne Volot, MD, Herve Chambost, MD PhD, Sophie Bayard, MD, Catherine Chatelanaz, Catherine Doriat-Robin, Yves Gruel, MD PhD, Agnès Veyradier, Sr., MD PhD, Jenny Goudemand, MD PhD, Sylvia Von Mackensen, PhD

Blood (2017) 130 (Supplement 1): 4866.

https://doi.org/10.1182/blood.V130.Suppl_1.4866.4866

Published: 2017

Journal Articles

Characterization of 5B9, a Chimeric Monoclonal Anti-PF4/H Antibody with a Human Fc Fragment and Which Mimics the Effects of HIT Human Antibodies

Jérome Rollin, PhD, Claire Kizlik-Masson, Steven McKenzie, MD PhD, Anne Poupon, PhD, Yuhang Zhou, MD, Caroline Vayne, Gaël Champier, PhD, Claire Pouplard, Pharm D, PhD, Yves Gruel, MD

Blood (2016) 128 (22): 138.

https://doi.org/10.1182/blood.V128.22.138.138

Published: 2016

Journal Articles

Wish-Qol Study - Assessment of Health-Related Quality of Life (HRQoL) and Health-Economic Aspects in Patients with Von Willebrand Disease (VWD) in France: Results of the Women Cohort

Annie Borel-Derlon, MD PhD, Jenny Goudemand, MD PhD, Dominique Desprez, MD, Fabienne Volot, MD, Yves Gruel, MD, Sophie Bayard, MD, Catherine Chatelanaz, Catherine Doriat-Robin, Agnes Veyradier, MD PhD, Edith Fressinaud, MD, Sylvia von Mackensen, PhD

Blood (2016) 128 (22): 1395.

https://doi.org/10.1182/blood.V128.22.1395.1395

Published: 2016

Journal Articles

Beneficial Effect of Exogenous PF4 on SRA for Detecting Pathogenic HIT Antibodies

Caroline Vayne, Jérome Rollin, PhD, Eve Anne Guery, Claire Kizlik-Masson, Anne Bauters, Pharm D, Yves Gruel, MD, Claire Pouplard, Pharm D, PhD

Blood (2016) 128 (22): 3733.

https://doi.org/10.1182/blood.V128.22.3733.3733

Published: 2016

Journal Articles

Inhibitor Development in Previously Untreated Patients with Severe Hemophilia a Treated with Nuwiq ® , a New Generation Recombinant FVIII of Human Origin

Blood (2016) 128 (22): 327.

https://doi.org/10.1182/blood.V128.22.327.327

Published: 2016

Journal Articles

Influence of FcγRIIA H131R Polymorphism on the Risk of Thrombosis in HIT and Variable Effect of Normal IgG on Platelet Activation

Jerôme Rollin, PhD, Claire Pouplard, Dorothee Leroux, Armand Saada, Céline Behier, Valérie Gouilleux Gruart, Gilles Thibault, PharmD, Yves Gruel, MD PhD

Blood (2014) 124 (21): 234.

https://doi.org/10.1182/blood.V124.21.234.234

Published: 2014

Journal Articles

Prospective Evaluation of a Rapid Nanoparticle-Based Lateral Flow Immunoassay (Stic Expert HIT ® ) for the Diagnosis of Heparin-Induced Thrombocytopenia

Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Nathalie Hezard, MD, PhD, Aurelien Lebreton, MD, Anne Bauters, MD, William Cohen, Emmanuel De Maistre, MD, Isabelle Diaz, Pharm D, Marie-Genevieve Huisse, Catherine Ternisien, MD, Sophie Voisin, MD, Yves Gruel, MD, PhD

Blood (2012) 120 (21): 1087.

https://doi.org/10.1182/blood.V120.21.1087.1087

Published: 2012

Journal Articles

Incidence of Antibodies to Protamine/Heparin Complexes in Cardiac Surgery Patients and Impact on Platelet Activation in Vitro and Clinical Outcome

Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Jerôme Rollin, PhD, Amiral Jean, PhD, May Marc Antoine, MD, Aupart Michel, MD, Yves Gruel, MD, PhD

Blood (2011) 118 (21): 2217.

https://doi.org/10.1182/blood.V118.21.2217.2217

Published: 2011

Journal Articles

Environmental Risk Factors of Inhibitor in Mild/Moderate Hemophilia A Patients Included in the FranceCoag Network

Roseline d'Oiron, MD, Virginie Demiguel, MSc, Annie Borel-Derlon, MD, PhD, Ségolène Donadel-Claeyssens, MD, PhD, Jenny Goudemand, MD, PhD, Benoît Guillet, MD, PhD, Yves Gruel, MD, PhD, Valérie Roussel-Robert, MD, Fabienne Volot, MD, Thierry Calvez, MD, MSc

Blood (2011) 118 (21): 1213.

https://doi.org/10.1182/blood.V118.21.1213.1213

Published: 2011

Journal Articles

Interleukin-10 Promoter Microsatellite Polymorphisms Influence the Immune Response to Heparin and the risk of Heparin-Induced Thrombocytopenia.

Claire Pouplard, PharmD, PhD, Pascale Cornillet-Lefebvre, PharmD, PhD, Redha Attaoua, PharmD, PhD, Dorothee Leroux, PharmD, Florin Grigorescu, MD, PhD, Carinne Lecoq-Lafon, Jerôme Rollin, PhD, Philippe Nguyen, MD, PhD, Yves Gruel, MD

Blood (2010) 116 (21): 3682.

https://doi.org/10.1182/blood.V116.21.3682.3682

Published: 2010

Journal Articles

Influence of Protein Tyrosine Phosphatase Polymorphisms on the Development of Antibodies to Platelet Factor 4 and the Risk of Heparin-Induced Thrombocytopenia.

Jerôme Rollin, PhD, Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Marc-Antoine May, MD, Yves Gruel, MD

Blood (2010) 116 (21): 3683.

https://doi.org/10.1182/blood.V116.21.3683.3683

Published: 2010

Journal Articles

Tumor Expression of Alternative Spliced Tissue Factor Is a Prognostic Marker in Non-Small Cell Lung Cancer.

Sandra Regina, MD, Jerome Rollin, PhD, Yves Gruel, MD

Blood (2009) 114 (22): 335.

https://doi.org/10.1182/blood.V114.22.335.335

Published: 2009

Journal Articles

Polymorphisms in TNFA and CTLA-4 Genes and the Risk of Heparin Induced Thrombocytopenia.

Dorothee Leroux, Claire Pouplard, PharmD, PhD, Benoit Guillet, MD, PhD, Beatrice Cosne, Marc Antoine May, MD, Yves Gruel, MD

Blood (2008) 112 (11): 3414.

https://doi.org/10.1182/blood.V112.11.3414.3414

Published: 2008

Journal Articles

Predictive Factors for Poor Outcome in Danaparoid-Treated HIT-Patients: A French Multicentre Case-Control Study.

IsmaïL. Elalamy, B. Tardy-Poncet, A. Mulot, E. DeMaistre, Claire Pouplard, Philippe Nguyen, M. Trossaert, Y. Blanloeil, B. Cleret, Yves Gruel, MD, T. Lecompte, B. Tardy

Blood (2008) 112 (11): 1984.

https://doi.org/10.1182/blood.V112.11.1984.1984

Published: 2008

Journal Articles

Alterations of P53 and PTEN Genes Are Associated with Increased TF Expression and Reduced Survival in Non Small Cell Lung Cancer

Sandra Regina, MD, Jean-Baptiste Valentin, Sébastien Lachot, Bruno Giraudeau, MD, Jerome Rollin, PhD, Yves Gruel, MD

Blood (2008) 112 (11): 1032.

https://doi.org/10.1182/blood.V112.11.1032.1032

Published: 2008

Journal Articles

A New Enzyme Immuno-Assay That Only Detects IgG Antibodies to Heparin-PF4 Complexes (Zymutest HIA IgG®) Improves the Specificity of the Diagnosis of HIT without Loss of Sensitivity.

Claire Pouplard, PharmD, PhD, Sandra Regina, MD, Jean Baptiste Valentin, Yves Gruel, MD

Blood (2007) 110 (11): 2096.

https://doi.org/10.1182/blood.V110.11.2096.2096

Published: 2007

NARROW

Genome-Wide Association Study Identifies Variation in ABO As Risk Factor for Platelet Reactivity in Heparin-Induced Thrombocytopenia

Is There an Alternative to Serotonin Release Assay for the Diagnosis of Heparin Induced Thrombocytopenia (HIT)? Evaluation of 5 Other Functional Methods Using 5B9 a Monoclonal IgG That Mimics HIT Human Antibodies

Cleavage of Anti-PF4/H IgG Antibodies By Ides, and Potential Benefit in the Treatment of Heparin-Induced Thrombocytopenia

Frequency of Anti-PF4/Heparin Antibodies in Patients Treated with Extra-Corporeal Membrane Oxygenation and Detection By Sensitized Serotonin Release Assay of Pathogenic Heparin-Induced Thrombocytopenia Antibodies

Gastrointestinal Bleeding and Angiodysplasia in Von Willebrand Disease: Results from the Ongoing French HRQoL Study: Wish-Qol

Characterization of 5B9, a Chimeric Monoclonal Anti-PF4/H Antibody with a Human Fc Fragment and Which Mimics the Effects of HIT Human Antibodies

Wish-Qol Study - Assessment of Health-Related Quality of Life (HRQoL) and Health-Economic Aspects in Patients with Von Willebrand Disease (VWD) in France: Results of the Women Cohort

Beneficial Effect of Exogenous PF4 on SRA for Detecting Pathogenic HIT Antibodies

Inhibitor Development in Previously Untreated Patients with Severe Hemophilia a Treated with Nuwiq ® , a New Generation Recombinant FVIII of Human Origin

Influence of FcγRIIA H131R Polymorphism on the Risk of Thrombosis in HIT and Variable Effect of Normal IgG on Platelet Activation

Prospective Evaluation of a Rapid Nanoparticle-Based Lateral Flow Immunoassay (Stic Expert HIT ® ) for the Diagnosis of Heparin-Induced Thrombocytopenia

Incidence of Antibodies to Protamine/Heparin Complexes in Cardiac Surgery Patients and Impact on Platelet Activation in Vitro and Clinical Outcome

Environmental Risk Factors of Inhibitor in Mild/Moderate Hemophilia A Patients Included in the FranceCoag Network

Interleukin-10 Promoter Microsatellite Polymorphisms Influence the Immune Response to Heparin and the risk of Heparin-Induced Thrombocytopenia.

Influence of Protein Tyrosine Phosphatase Polymorphisms on the Development of Antibodies to Platelet Factor 4 and the Risk of Heparin-Induced Thrombocytopenia.

Tumor Expression of Alternative Spliced Tissue Factor Is a Prognostic Marker in Non-Small Cell Lung Cancer.

Polymorphisms in TNFA and CTLA-4 Genes and the Risk of Heparin Induced Thrombocytopenia.

Predictive Factors for Poor Outcome in Danaparoid-Treated HIT-Patients: A French Multicentre Case-Control Study.

Alterations of P53 and PTEN Genes Are Associated with Increased TF Expression and Reduced Survival in Non Small Cell Lung Cancer

A New Enzyme Immuno-Assay That Only Detects IgG Antibodies to Heparin-PF4 Complexes (Zymutest HIA IgG®) Improves the Specificity of the Diagnosis of HIT without Loss of Sensitivity.

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American Society of Hematology

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American Society of Hematology

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