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Yves Beuzard, MD
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Journal Articles

Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia

Laurent Kiger, Sandia Adypagavane, Laura Bencheikh, PhD, Nicolas Hebert, Stephane Moutereau, MD, Frédéric Galactéros, MD PhD, Michael Marden, PhD, Yves Beuzard, MD, France Pirenne, MD PhD, Pablo Bartolucci, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3381.
https://doi.org/10.1182/blood-2019-130600
Published: 2019
Journal Articles

Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy

Marina Cavazzana, MD PhD, Salima Hacein-Bey-Abina, Pharm.D.,PhD, Emmanuel Payen, Elisa Magrin, PhD, Alessandra Magnani, MD PhD, Michaela Semeraro, Laure Caccavelli, Fabien Touzot, MD PhD, Francois Lefrere, Sr., Felipe Suarez, MDPhD, Olivier Hermine, Valentine Brousse, MD, Catherine Poirot, Despina Moshous, Philippe Bourget, PhD, Wassim El Nemer, PhD, Pablo Bartolucci, MD PhD, Leslie Weber, Herve Puy, MD, Jean-François Meritet, David Grévent, MD, Yves Beuzard, MD, Stany Chretien, Thibaud Lefebvre, Mohammed Asmal, MD PhD, Alexandra Laura Miller, Mariane De Montalembert, MD PhD, Stephane Blanche, MD, Philippe Leboulch, MD, Jean-Antoine Ribeil, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4609.
https://doi.org/10.1182/blood.V130.Suppl_1.4609.4609
Published: 2017
Journal Articles

Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies

Jean-Antoine Ribeil, MD PhD, Salima Hacein-Bey-Abina, Pharm.D., PhD, Emmanuel Payen, PhD, Michaela Semeraro, PhD, Magrin Elisa, PhD, Laure Caccavelli, PhD, Fabien Touzot, MD PhD, Francois Lefrere, MD, Felipe Suarez, MD PhD, Olivier Hermine, MD PhD, Valentine Brousse, MD, Catherine Poirot, MD PhD, Benedicte Neven, MD PhD, Philippe Bourget, PharmD, PhD, Wassim El Nemer, PhD, Pablo Bartolucci, MD PhD, Leslie Weber, MSc, Hervé Puy, MD PhD, Jean-François Méritet, PhD, David Grevent, MD, Yves Beuzard, MD, Stany Chrétien, MD, Thibaud Lefebvre, MD, Mohammed Asmal, MD PhD, Marcelyne Joseney-Antoine, Mariane De Montalembert, MD PhD, Stephane Blanche, MD, Philippe Leboulch, MD, Marina Cavazzana, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2311.
https://doi.org/10.1182/blood.V128.22.2311.2311
Published: 2016
Journal Articles

Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector

Marina Cavazzana, MD PhD, Jean-Antoine Ribeil, MD PhD, Emmanuel Payen, MD, Felipe Suarez, MD PhD, Yves Beuzard, MD, Fabien Touzot, MDPhD, Resy Cavallesco, PhD, Francois Lefrere, MD, Stany Chretien, MD, Philippe Bourget, PharmD, PhD, Fabrice Monpoux, MD, Corinne Pondarre, Benedicte Neven, Manfred Schmidt, PhD, Christof von Kalle, MD, Frans A. Kuypers, PhD, Laura Sandler, MPH, Sandeep Soni, MD, Olivier Hermine, Stephane Blanche, MD, Mariane De Montalembert, MD, Salima Hacien-Bey-Abina, PharmD, PhD, Philippe Leboulch, MD
Journal: Blood
Blood (2015) 126 (23): 202.
https://doi.org/10.1182/blood.V126.23.202.202
Published: 2015
Journal Articles

Study Hgb-205: Outcomes of Gene Therapy for Hemoglobinopathies Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral β Α-T87Q -Globin Vector (LentiGlobin ® BB305 Drug Product)

Marina Cavazzana, MD PhD, Jean-Antoine Ribeil, MD PhD, Emmanuel Payen, Felipe Suarez, MD PhD, Yves Beuzard, MD, Fabien Touzot, MDPhD, Resy Cavallesco, PhD, Francois Lefrère, MD, Stany Chretien, Phillipe Bourget, Fabrice Monpoux, Corrine Pondarre, Benedicte Neven, MD, Manfred Schmidt, PhD, Christof von Kalle, MD, Laura Sandler, MPH, Sandeep Soni, MD, Olivier Hermine, Stephanie Blanche, Mariane De Montalembert, MD, Salima Hacein-Bey-Abina, Pharm.D., PhD, Philippe Leboulch, MD
Journal: Blood
Blood (2014) 124 (21): 4797.
https://doi.org/10.1182/blood.V124.21.4797.4797
Published: 2014
Journal Articles

Modulation of Activin Signaling by RAP-011 (ActRIIA-IgG1) Improve Anemia, Increases Hemoglobin Levels and Corrects Ineffective Erythropoiesis in β-Thalassemia

Michael Dussiot, Thiago Maciel, PhD, Aurelie Fricot, Joel Veiga, Etienne Paubelle, Emmanuel Payen, Yves Beuzard, MD, Jean-Antoine Ribeil, MD, PhD, Jean-Benoît Arlet, MD, Genevieve Courtois, PhD, Tom O Daniel, MD, PhD, Rajesh Chopra, MD, PhD, Victoria Sung, Ph.D., Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD
Journal: Blood
Blood (2012) 120 (21): 247.
https://doi.org/10.1182/blood.V120.21.247.247
Published: 2012
Journal Articles

Heat-Shock Protein-70, -27 and Peroxiredoxin-2 Show Chaperone Function in Sickle Red Cells: Evidences from Transgenic Sickle Cell Mouse Model.

Andrea Biondani, PhD, Franco Turrini, MD, Alessandro Matte’, Franco Carta, PhD, Alida Filippini, MD, Yves Beuzard, MD, Lucia De Franceschi, MD
Journal: Blood
Blood (2007) 110 (11): 845.
https://doi.org/10.1182/blood.V110.11.845.845
Published: 2007
Journal Articles

PDE-4 Inhibitor Rolipram Prevents Hypoxia Induced Pulmonary Hypertension in Transgenic Sickle Cell Sad Mice.

Lucia De Franceschi, MD, Giorgio Malpeli, Anne Janin, MD, Aldo Scarpa, MD, Christhophe Leboeuf, Orah Platt, MD, Philippe Leboulch, Emmanuel Payen, Yves Beuzard, MD, Carlo Brugnara, MD
Journal: Blood
Blood (2004) 104 (11): 3577.
https://doi.org/10.1182/blood.V104.11.3577.3577
Published: 2004
Journal Articles

Protective Effects of No-Albumin and Albumin on Lung Injury Induced by Hypoxia/Reoxygenation in a Mouse Model of Sickle Cell Disease.

Lucia De Franceschi, MD, Giorgio Malpeli, Anne Janin, MD, Eva Muchitsch, Aldo Scarpa, MD, Philippe Leboulch, Christhope Leboeuf, Yves Beuzard, MD, Carlo Brugnara, MD
Journal: Blood
Blood (2004) 104 (11): 3580.
https://doi.org/10.1182/blood.V104.11.3580.3580
Published: 2004