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Journal Articles

CAL-101, a Specific Inhibitor of the p110δ Isoform of Phosphatidylinositide 3-Kinase Induces Cytotoxicity in Multiple Myeloma (MM)

Hiroshi Ikeda, MD, PhD, Teru Hideshima, MD, PhD, Yutaka Okawa, MD, PhD, Sonia Vallet, MD, Samantha Pozzi, Loredana Santo, MD, Gullu Gorgun, Mariateresa Fulciniti, Noopur S. Raje, MD, Giulia Perrone, Nikhil Munshi, MD, Paul Richardson, MD, Brian J Lannutti, Kamal D. Puri, Neill A. Giese, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 2753.

https://doi.org/10.1182/blood.V112.11.2753.2753

Published: 2008

Journal Articles

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Loredana Santo, MD, Sonia Vallet, M.D., Teru Hideshima, M.D., Ph.D., Diana Cirstea, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, Gullu Gorgun, PhD, Giulia Perrone, MD, Elisabetta Calabrese, MD, Matthew S Squires, Marco Ladetto, MD, Nikhil C. Munshi, MD, Mario Boccadoro, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2008) 112 (11): 251.

https://doi.org/10.1182/blood.V112.11.251.251

Published: 2008

Journal Articles

In Vivo Effects of Zoledronic Acid on Bone Remodeling.

Samantha Pozzi, MD, Teru Hideshima, MD, Sonia Vallet, MD, Siddhartha Mukherjee, MD, Shweta Chhetri, Diana Cirstea, MD, Nileshwari Vaghela, Clare Thomas, Dilani Rosa, Hiroshi Ikeda, MD, Yutaka Okawa, MD, Tanyel Kiziltepe, PhD, Jesse Schoonmaker, Ernestina Schipani, MD, Mary Bouxsein, PhD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2007) 110 (11): 3520.

https://doi.org/10.1182/blood.V110.11.3520.3520

Published: 2007

Journal Articles

Targeting CCR1 for the Treatment of Osteolytic Bone Disease in Multiple Myeloma.

Sonia Vallet, MD, Noopur Raje, MD, MariaTeresa Fulciniti, Kenji Ishitsuka, MD, Teru Hideshima, MD, Klaus Podar, MD, Samantha Pozzi, MD, Iris Breitkreutz, MD, Tanyel Kiziltepe, PhD, Yutaka Okawa, MD, Hiroshi Ikeda, MD, Loredana Santo, MD, Siddhartha Mukherjee, MD, Nileshwari Vaghela, Diana Cirstea, MD, Mario Boccadoro, MD, Kenneth C. Anderson, MD

Blood (2007) 110 (11): 2503.

https://doi.org/10.1182/blood.V110.11.2503.2503

Published: 2007

Journal Articles

Preclinical Validation of a Clinical Grade Novel Specific Small Molecule Cyclin D1 Inhibitor, P276-00 for the Treatment of Multiple Myeloma.

Blood (2007) 110 (11): 256.

https://doi.org/10.1182/blood.V110.11.256.256

Published: 2007

Journal Articles

Multiple Myeloma Cell-Osteoblast Interaction Results in Impaired Bone Formation.

Sonia Vallet, MD, Teru Hideshima, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Gaurav Gharti-Chhetri, Siddhartha Mukherjee, MD, Iris Breitkreutz, MD, Tanyel Kiziltepe, PhD, Yutaka Okawa, MD, Hiroshi Ikeda, MD, Loredana Santo, MD, Diana Cirstea, MD, Mario Boccadoro, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2007) 110 (11): 4764.

https://doi.org/10.1182/blood.V110.11.4764.4764

Published: 2007

Journal Articles

Delineation of Canonical and Non-Canonical NF-κB Pathways in Multiple Myeloma: Therapeutic Implications.

Teru Hideshima, MD, PhD, Noopur Raje, MD, Ruben Carrasco, MD, PhD, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, PhD, Tanyel Kiziltepe, PhD, Sonia Valet, MD, Samantha Pozzi, MD, Dharminder Chauhan, PhD, Constantine Mitsiades, MD, PhD, Klaus Podar, MD, PhD, Yu-Tzu Tai, PhD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD

Blood (2007) 110 (11): 670.

https://doi.org/10.1182/blood.V110.11.670.670

Published: 2007

Journal Articles

CCR1 Inhibition Impairs Osteoclast Activity and Interaction with Myeloma Cells.

Sonia Vallet, MD, Noopur Raje, MD, Kenji Ishitsuka, MD, Teru Hideshima, MD, Klaus Podar, MD, Tanyel Kizeltepe, PHD, Hiroshi Yasui, MD, Shweta Chhetri, Enrique M. Ocio, MD, Janice Jin, Yutaka Okawa, MD, Hiroshi Ikeda, MD, Mario Boccadoro, MD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 3494.

https://doi.org/10.1182/blood.V108.11.3494.3494

Published: 2006

Journal Articles

Serotonin Receptor Antagonists Have an In Vitro and In Vivo Anti-Myeloma Effect That Is Mainly Mediated by Caspase Dependent Apoptosis.

Enrique M. Ocio, MD, PhD, Teru Hideshima, MD, PhD, Hiroshi Yasui, MD, PhD, Kiziltepe Tanyel, PhD, Hirosi Ikeda, MD, PhD, Yutaka Okawa, MD, PhD, Sonia Vallet, MD, Janice Jin, MD, Kenji Ishitsuka, MD, PhD, Noopur Raje, MD, Laurence Catley, MD, MBBS, FRACP, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 2597.

https://doi.org/10.1182/blood.V108.11.2597.2597

Published: 2006

Journal Articles

Akt Inhibitor Perifosine-Induced Cytotoxicity Is Associated with Significant Downregulation of Survivin in Human Multiple Myeloma (MM) Cells.

Teru Hideshima, MD, PhD, Hiroshi Yasui, MD, PhD, Laurence Catley, MD, Noopur Raje, MD, Dharminder Chauhan, PhD, Kenji Ishitsuka, MD, PhD, Klaus Podar, MD, PhD, Constantine Mitsiades, MD, PhD, Yu-Tzu Tai, PhD, Sonia Vallet, MD, Tanyel Kizitepe, PhD, Enrique Ocio, MD, PhD, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, PhD, Hiromasa Hideshima, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 3410.

https://doi.org/10.1182/blood.V108.11.3410.3410

Published: 2006

Journal Articles

Epigenetic Modulation by Vidaza™ induces Apoptosis and Overcomes In Vitro Drug Resistance in Human Multiple Myeloma Cells.

Tanyel Kiziltepe, PhD, Laurence Catley, MD, Teru Hideshima, MD,PhD, Noopur Raje, MD, Hiroshi Yasui, MD,PhD, Sonia Vallet, MD, Hiroshi Ikeda, MD,PhD, Yutaka Okawa, MD,PhD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 5001.

https://doi.org/10.1182/blood.V108.11.5001.5001

Published: 2006

NARROW

CAL-101, a Specific Inhibitor of the p110δ Isoform of Phosphatidylinositide 3-Kinase Induces Cytotoxicity in Multiple Myeloma (MM)

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

In Vivo Effects of Zoledronic Acid on Bone Remodeling.

Targeting CCR1 for the Treatment of Osteolytic Bone Disease in Multiple Myeloma.

Preclinical Validation of a Clinical Grade Novel Specific Small Molecule Cyclin D1 Inhibitor, P276-00 for the Treatment of Multiple Myeloma.

Multiple Myeloma Cell-Osteoblast Interaction Results in Impaired Bone Formation.

Delineation of Canonical and Non-Canonical NF-κB Pathways in Multiple Myeloma: Therapeutic Implications.

CCR1 Inhibition Impairs Osteoclast Activity and Interaction with Myeloma Cells.

Serotonin Receptor Antagonists Have an In Vitro and In Vivo Anti-Myeloma Effect That Is Mainly Mediated by Caspase Dependent Apoptosis.

Akt Inhibitor Perifosine-Induced Cytotoxicity Is Associated with Significant Downregulation of Survivin in Human Multiple Myeloma (MM) Cells.

Epigenetic Modulation by Vidaza™ induces Apoptosis and Overcomes In Vitro Drug Resistance in Human Multiple Myeloma Cells.

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American Society of Hematology

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American Society of Hematology

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