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Journal Articles

Final Results From a Phase II Trial of Triapine® Plus Fludarabine for Adults with Aggressive Myeloproliferative Disorders

Michael A McDevitt, MD, PhD, Robert L Dilley, Keith W. Pratz, MD, B. Douglas Smith, MD, Alison R. Moliterno, MD, Yun Yen, MD, PhD, Lisa Malick, RN, Steven D. Gore, MD, Richard J. Jones, Jaroslaw P. Maciejewski, MD, PhD, Igor Espinoza-Delgado, MD, Judith E. Karp, MD
Journal: Blood
Blood (2011) 118 (21): 1755.
https://doi.org/10.1182/blood.V118.21.1755.1755
Published: 2011
Journal Articles

Combination Therapy with the Histone Deacetylase Inhibitor Vorinostat Plus the Novel Aurora Kinase A Inhibitor MK-5108 Leads to Enhanced Lymphoma Cell Death Due to Acetylation of p53 and Repression of c-Myc, hTERT, and miRNA Levels.

Leo Kretzner, Anna Scuto, Kowolik Claudia, Richard Jove, Stephen J Forman, MD, Yun Yen, MD, PhD, Mark Kirschbaum, MD
Journal: Blood
Blood (2009) 114 (22): 1690.
https://doi.org/10.1182/blood.V114.22.1690.1690
Published: 2009
Journal Articles

Preliminary Results from a Phase II Trial of Triapine Plus Fludarabine for Adults with Aggressive Myeloproliferative Disorders

Michael A McDevitt, Judith E. Karp, Yun Yen, MD, PhD, Jaroslaw Maciejewski, Igor Espinoza-Delgado
Journal: Blood
Blood (2008) 112 (11): 2811.
https://doi.org/10.1182/blood.V112.11.2811.2811
Published: 2008
Journal Articles

Combination Therapy with Histone Deacetylase Inhibitor Vorinostat Plus Aurora Kinase Inhibitor MK-0457 Leads to Enhanced Lymphoma Cell Killing with Stabilization of p53 and Repression of C-Myc, hTERT, and Myc-Responsive miRNAs

Leo Kretzner, Anna Scuto, Richard Jove, Stephen J. Forman, MD, Yun Yen, MD, PhD, Mark Kirschbaum, MD
Journal: Blood
Blood (2008) 112 (11): 3628.
https://doi.org/10.1182/blood.V112.11.3628.3628
Published: 2008
Journal Articles

The Novel Histone Deacetylase Inhibitor, LBH589, Induces Expression of DNA Damage Response Genes and Apoptosis in Ph-Acute Lymphoblastic Leukemia Cells.

Scuto Anna, PhD, Mark H. Kirschbaum, MD, Peter Atadja, Agnes Juhasz, Vinod Pullarkat, MD, Ravi Bhatia, MD, Stephen J. Forman, MD, Yun Yen, MD, PhD, Richard Jove, PhD
Journal: Blood
Blood (2007) 110 (11): 2796.
https://doi.org/10.1182/blood.V110.11.2796.2796
Published: 2007
Journal Articles

Combination of the Histone Deacetylase Inhibitor Vorinostat and Dasatinib Increases Apoptosis in Bcr-abl+ Cells and Reverses Changes Associated with CML Progression.

Leo Kretzner, PhD, Anna Scuto, PhD, Agnes Juhasz, PhD, Richard Jove, PhD, Yun Yen, MD, Stephen J. Forman, MD, Mark Kirschbaum
Journal: Blood
Blood (2006) 108 (11): 2165.
https://doi.org/10.1182/blood.V108.11.2165.2165
Published: 2006