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Journal Articles

Genotype-Phenotype Correlation in Congenital TTP: New Insights from a Multicentre Study with 121 Patients

Anette Anette Van Dorland, PhD, Magnus Mansouri Taleghani, MD, Kenneth Dale Friedman, MD, James George, MD, Ingrid Hrachovinova, PhD, Paul Knöbl, MD PhD, Bernhard Lammle, MD, Masanori Matsumoto, MD, Anne Sophie von Krogh, MD, Reinhard Schneppenheim, MDPhD, Isabella Aebi-Huber, Bütikofer Lukas, PhD, Zuzana Cermakova, PhD, Petter Quist-Paulsen, MD PhD, Deirdra Terrell, PhD, Sara K. Vesely, PhD MPH, Yoshihiro Fujimura, MD PhD, Johanna A. Kremer Hovinga Strebel, MD

Blood (2018) 132 (Supplement 1): 376.

https://doi.org/10.1182/blood-2018-99-112095

Published: 2018

Journal Articles

Quantification of the Actual Numbers of Transplantable CD34 + CD133 + Hematopoietic Stem Cells Residing in the Umbilical Cord Blood (UCB) Units: A New Indicator of Quality Assurance of UCB Units

Yoshikazu Matsuoka, PhD, Tatsuya Fujioka, MD, PhD, Keisuke Sumide, Phar.B., Kazuo Hatanaka, MD, Fumiaki Nakamura, MD, PhD, Kayoko Matsumoto, PhD, Satoshi Otani, M.T., Takafumi Kimura, MD, PhD, Yoshihiro Fujimura, MD, PhD, Hiroaki Asano, PhD, Yoshiaki Sonoda, MD, PhD

Blood (2016) 128 (22): 1465.

https://doi.org/10.1182/blood.V128.22.1465.1465

Published: 2016

Journal Articles

Severe Reduction of Free ADAMTS13, Unbound to Von Willebrand Factor, in Plasma Milieu Is a Unique Feature of HELLP Syndrome

Yoko Yoshida, PhD, Ayami Isonishi, Toshiyuki Sado, MD, PhD, Masaki Hayakawa, MD, Hideo Yagi, MD.PhD, Hiroshi Kobayashi, MD, PhD, Yoshihiro Fujimura, MD, PhD, Masanori Matsumoto, MD.PhD

Blood (2016) 128 (22): 134.

https://doi.org/10.1182/blood.V128.22.134.134

Published: 2016

Journal Articles

Quantitative ELISA Using N10 Antibody, Targeting on VWF-Y1605 Residue, Indicates That N-Linked Blood Group Type A Carbohydrate on VWF Molecule Functions Against ADAMTS13 Cleavage

Masaki Hayakawa, MD, Seiji Kato, PhD, Taei Matsui, PhD, Kazuya Sakai, MD, Yumi Yoshii, MD, Hideo Yagi, MD.PhD, Yoshihiro Fujimura, MD, PhD, Masanori Matsumoto, MD.PhD

Blood (2016) 128 (22): 3773.

https://doi.org/10.1182/blood.V128.22.3773.3773

Published: 2016

Journal Articles

Decreased Platelet Thrombus Size, Due to a Heightened Proteolysis of VWF By ADAMTS13, Is Quickly Restored after Valve Replacement in Aortic Stenosis Patients

Hideo Yagi, MD PhD, Masaki Hayakawa, MD, Naoko Yamaguchi, Keigo Yamashita, MD, Shigeki Taniguchi, MD PhD, Masanori Matsumoto, MD PhD, Kazuo Tsubaki, MD PhD, Yoshihiro Fujimura, MD PhD

Blood (2014) 124 (21): 2857.

https://doi.org/10.1182/blood.V124.21.2857.2857

Published: 2014

Journal Articles

Introduction of a Quick Assay for ADAMTS13 Activity Improved a Survival of Acquired TTP Patients Who Received Platelet Transfusions

Yumi Yoshii, MD, Masanori Matsumoto, MD PhD, Kurumatani Norio, MD PhD, Ayami Isonishi, BS, Masahito Uemura, MD PhD, Yuji Hori, PhD, Masaki Hayakawa, MD, Hideo Yagi, MD PhD, Charles L Bennett, MD PhD MPP, Yoshihiro Fujimura, MD PhD

Blood (2014) 124 (21): 4209.

https://doi.org/10.1182/blood.V124.21.4209.4209

Published: 2014

Journal Articles

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

Yoshihiro Fujimura, MD, PhD, Yumi Yoshii, MD, Masanori Matsumoto, MD, PhD, Ayami Isonishi, BS, Masaki Hayakawa, MD, Yoko Yoshida, MS, Hideo Yagi, MD, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD

Blood (2013) 122 (21): 3545.

https://doi.org/10.1182/blood.V122.21.3545.3545

Published: 2013

Journal Articles

Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis

Yoko Yoshida, MS, Xinping Fan, MD, Yoshifumi Ohyama, PhD, Tetsuro Kokubo, PhD, Masanori Matsumoto, MD, PhD, Hideo Yagi, MD, PhD, Hiroko Shirotani-Ikejima, PhD, Toshiyuki Miyata, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2013) 122 (21): 2318.

https://doi.org/10.1182/blood.V122.21.2318.2318

Published: 2013

Journal Articles

HSCT-Associated Hepatic VOD Is Initiated With Preceding Appearance Of Unusually Large Von Willebrand Factor Multimers In Patient Plasmas

Masaki Hayakawa, MD, Masanori Matsumoto, MD, PhD, Yumi Yoshii, MD, Hideo Yagi, MD, PhD, Hiroshi Kimura, MD, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2013) 122 (21): 3625.

https://doi.org/10.1182/blood.V122.21.3625.3625

Published: 2013

Journal Articles

International Registry for Patients with Hereditary Thrombotic Thrombocytopenic Purpura (TTP) – Upshaw-Schulman Syndrome

Magnus Mansouri Taleghani, Yoshihiro Fujimura, MD, PhD, James N. George, MD, Ingrid Hrachovinova, PhD, Paul Knoebl, MD, Bernhard Lämmle, MD, Petter Quist-Paulsen, MD, PhD, Reinhard Schneppenheim, MD, PhD, Johanna A. Kremer Hovinga Strebel, MD

Blood (2012) 120 (21): 4654.

https://doi.org/10.1182/blood.V120.21.4654.4654

Published: 2012

Journal Articles

Analysis of Genetic and Predisposing Factors in Japanese Patients with Atypical Hemolytic Uremic Syndrome

Xinping Fan, MD, Yoko Yoshida, MS, Toshiyuki Miyata, PhD, Shigenori Honda, MD, PhD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 3337.

https://doi.org/10.1182/blood.V120.21.3337.3337

Published: 2012

Journal Articles

Deficient ADAMTS13 Activity in Ticlopidine-Associated Thrombotic Thrombocytopenic Purpura (TTP) in Populations From Japan in 2012: Validation of Findings Initially Reported in the United States in 1998 and 2000.

Charles Bennett, MD, PhD, MPP, Masanori Matsumoto, MD, Peter Georgantopoulos, MPH, AM, Sony Jacob, MD, Brianne L Dunn, PharmD, Zaina Parvez Qureshi, PhD, MPH, Nicholas Bandarenko, III, MD, Hau C. Kwaan, MD, PhD, Jeffrey Winters, MD, Ravindra Sarode, MD, Joseph E Kiss, MD, Constance Danielson, MD, PhD, Thomas L. Ortel, MD, PhD, Thomas Raife, MD, William F Clark, MD, Gail Rock, PhD, MD, FRCP, X. Long Zheng, MD, PhD, Dennis Raisch, Ph.D., M.S., R.Ph., Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 2203.

https://doi.org/10.1182/blood.V120.21.2203.2203

Published: 2012

Journal Articles

Anti-ADAMTS13 Inhibitor Boosting During Plasma Exchange Therapy Often Causes an Intractable Acquired Idiopathic TTP

Ayami Isonishi, BS, Masanori Matsumoto, MD, PhD, Friedrich Scheiflinger, PhD, Barbara Plaimauer, PhD, Charles Bennett, MD, PhD, MPP, Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 1086.

https://doi.org/10.1182/blood.V120.21.1086.1086

Published: 2012

Journal Articles

The Ratio of ADAMTS13 to VWF-Propeptide Can Reflect the Disease Severity and the Extent of Inflammation of the Patients with Severe Sepsis or Septic Shock,

Kenji Nishio, MD, PhD, Hidetada Fukushima, MD, Tomoro Watanabe, MD, Tadahiko Seki, MD, Hideto Matsui, MD, PhD, Mitsuhiko Sugimoto, MD, PhD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Kazuo Okuchi, MD, PhD

Blood (2011) 118 (21): 3349.

https://doi.org/10.1182/blood.V118.21.3349.3349

Published: 2011

Journal Articles

A Large-Pore IEF Gel Electrophoresis Separates the Complex in Both of ADAMTS13 Bound to VWF and to the IgG Autoantibodies From the Unbound in Plasma Milieu

Masanori Matsumoto, MD, PhD, Ayami Isonishi, BS, Yuji Hori, BS, Masaki Hayakawa, MD, Kenji Soejima, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2011) 118 (21): 1160.

https://doi.org/10.1182/blood.V118.21.1160.1160

Published: 2011

Journal Articles

Quantitative Analysis of the Domain-Specific Autoantibodies to ADAMTS13 in Patients with Acquired Thrombotic Thrombocytopenic Purpura

Atsuko Igari, Takanori Moriki, MD, PhD, Yusuke Yamaguchi, Terumichi Nakagawa, Hideo Wada, MD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Kenji Soejima, PhD, Mitsuru Murata, MD

Blood (2011) 118 (21): 1167.

https://doi.org/10.1182/blood.V118.21.1167.1167

Published: 2011

Journal Articles

Characterization of Two Patient Groups with Acquired Idiopathic Thrombotic Thrombocytopenic Purpura, Defined by ADAMTS13 (n=195) and/or Classic Pentad (n=89).

Masanori Matsumoto, MD, Ayami Isonishi, BS, Seiji Kato, PhD, Hiromichi Ishizashi, PhD, Hideo Yagi, MD, Yoshihiro Fujimura, MD

Blood (2009) 114 (22): 3505.

https://doi.org/10.1182/blood.V114.22.3505.3505

Published: 2009

Journal Articles

Plasma ADAMTS13 Activity Markedly Decreases in Patients with Severe Acute Pancreatitis: Its Potential Role on the Development of Multiorgan Failure.

Chie Morioka, MD, Masahito Uemura, MD, Tomomi Matsuyama, MD, Masanori Matsumoto, MD, Seiji Kato, MD, Masatohsi Ishikawa, MD, Hiromichi Ishizashi, MD, Masao Fujimoto, MD, Tatsuhiro Tsujimoto, MD, Kenji Nishio, MD, Kazuo Okuchi, MD, Yoshihiro Fujimura, MD, Hiroshi Fukui, MD

Blood (2007) 110 (11): 2160.

https://doi.org/10.1182/blood.V110.11.2160.2160

Published: 2007

Journal Articles

Clinical and Outcomes Findings for Thrombotic Thrombocytopenic Purpura among 467 Persons with Severely Versus Not Severely Deficient ADAMTS-13 Levels.

Charles L. Bennett, MD, PhD, MPP, Thanh Ha Luu, BA, Anaadriana Zakarija, MD, Hau C. Kwaan, MD, PhD, Nicholas Bandarenko, MD, Dilip K. Pandey, MBBS, MS, PhD, John F. Cursio, MS, June M. McKoy, MD, JD, MPH, Charlie Buffie, BA, Jeffrey L. Winters, MD, Thomas L. Ortel, MD, Ravindra Sarode, MD, X. Long Zheng, MD, PhD, Thomas J. Raife, MD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Gail A. Rock, MD, PhD

Blood (2007) 110 (11): 2088.

https://doi.org/10.1182/blood.V110.11.2088.2088

Published: 2007

Journal Articles

Ticlopidine- and Clopidogrel-Associated Thrombotic Thrombocytopenic Purpura (TTP): Final Results from the Surveillance Epidemiology and Risk Factor-TTP Study Group.

Elizabeth A. Richey, BA, Charles L. Bennett, MD, PhD, MPP, Hau C. Kwaan, MD, PhD, Anaadriana Zakarija, MD, MSCI, Nicholas Banderanko, MD, Dilip K. Pandey, MD, PhD, June M. McKoy, MD, JD, MPH, Paul R. Yarnold, PhD, Dennis W. Raisch, PhD, Jeffrey L. Winters, MD, Thomas J. Raife, MD, John F. Cursio, MS, Matthew J. Fisher, Thomas L. Ortel, MD, PhD, Martin S. Tallman, MD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Joel L. Moake, MD

Blood (2007) 110 (11): 2089.

https://doi.org/10.1182/blood.V110.11.2089.2089

Published: 2007

NARROW

Genotype-Phenotype Correlation in Congenital TTP: New Insights from a Multicentre Study with 121 Patients

Quantification of the Actual Numbers of Transplantable CD34 + CD133 + Hematopoietic Stem Cells Residing in the Umbilical Cord Blood (UCB) Units: A New Indicator of Quality Assurance of UCB Units

Severe Reduction of Free ADAMTS13, Unbound to Von Willebrand Factor, in Plasma Milieu Is a Unique Feature of HELLP Syndrome

Quantitative ELISA Using N10 Antibody, Targeting on VWF-Y1605 Residue, Indicates That N-Linked Blood Group Type A Carbohydrate on VWF Molecule Functions Against ADAMTS13 Cleavage

Decreased Platelet Thrombus Size, Due to a Heightened Proteolysis of VWF By ADAMTS13, Is Quickly Restored after Valve Replacement in Aortic Stenosis Patients

Introduction of a Quick Assay for ADAMTS13 Activity Improved a Survival of Acquired TTP Patients Who Received Platelet Transfusions

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis

HSCT-Associated Hepatic VOD Is Initiated With Preceding Appearance Of Unusually Large Von Willebrand Factor Multimers In Patient Plasmas

International Registry for Patients with Hereditary Thrombotic Thrombocytopenic Purpura (TTP) – Upshaw-Schulman Syndrome

Analysis of Genetic and Predisposing Factors in Japanese Patients with Atypical Hemolytic Uremic Syndrome

Deficient ADAMTS13 Activity in Ticlopidine-Associated Thrombotic Thrombocytopenic Purpura (TTP) in Populations From Japan in 2012: Validation of Findings Initially Reported in the United States in 1998 and 2000.

Anti-ADAMTS13 Inhibitor Boosting During Plasma Exchange Therapy Often Causes an Intractable Acquired Idiopathic TTP

The Ratio of ADAMTS13 to VWF-Propeptide Can Reflect the Disease Severity and the Extent of Inflammation of the Patients with Severe Sepsis or Septic Shock,

A Large-Pore IEF Gel Electrophoresis Separates the Complex in Both of ADAMTS13 Bound to VWF and to the IgG Autoantibodies From the Unbound in Plasma Milieu

Quantitative Analysis of the Domain-Specific Autoantibodies to ADAMTS13 in Patients with Acquired Thrombotic Thrombocytopenic Purpura

Characterization of Two Patient Groups with Acquired Idiopathic Thrombotic Thrombocytopenic Purpura, Defined by ADAMTS13 (n=195) and/or Classic Pentad (n=89).

Plasma ADAMTS13 Activity Markedly Decreases in Patients with Severe Acute Pancreatitis: Its Potential Role on the Development of Multiorgan Failure.

Clinical and Outcomes Findings for Thrombotic Thrombocytopenic Purpura among 467 Persons with Severely Versus Not Severely Deficient ADAMTS-13 Levels.

Ticlopidine- and Clopidogrel-Associated Thrombotic Thrombocytopenic Purpura (TTP): Final Results from the Surveillance Epidemiology and Risk Factor-TTP Study Group.

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American Society of Hematology

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American Society of Hematology

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