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Ye Chen, PhD
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Journal Articles

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Michael Andreeff, MD, PhD, Rui-yu Wang, MD, PhD, Richard E. Davis, M.D., Rodrigo Jacamo, PhD, Peter P. Ruvolo, PhD, Teresa McQueen, BS, Xielin Huang, PhD, Venkata L Battula, Ph.D., Ye Chen, PhD, Shonali Majumdar, Juliana M Benito, PhD, Zhihong Zeng, MD, Christopher B. Benton, MD, Bing Z Carter, PhD, Hong Mu, MD, PhD, Wencai Ma, Ph.D., Vivian R Ruvolo, MA, Lauren Hodgson, Sergej Konoplev, MD, PhD, Rongqing Pan, MS, Anitha Somanchi, Dirk Strunck, Qiguo Zhang, Steven M. Kornblau, MD, Hagop M Kantarjian, MD, Guido Marcucci, MD, Ramiro Garzon, MD, Johannes Zuber, Scott W. Lowe, PhD, Carlo M. Croce, MD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3685.
https://doi.org/10.1182/blood.V122.21.3685.3685
Published: 2013
Journal Articles

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Venkata L Battula, Ph.D., Juliana M Benito, PhD, Anitha Somanchi, Seshagiri Duvvuri, Lauren Hodgson, Ye Chen, PhD, Wencai Ma, Ph.D., Richard E. Davis, M.D., Ian K. McNiece, PhD, Elizabeth J Shpall, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2457.
https://doi.org/10.1182/blood.V122.21.2457.2457
Published: 2013
Journal Articles

SDF-1 Inhibition Using Spiegelmer ® Nox-A12 As a Novel Strategy For Targeting AML Cells Within Their BM Microenvironment

Rodrigo Jacamo, PhD, Zhihong Zeng, MD, Ye Chen, PhD, Yuexi Shi, Teresa McQueen, BS, Anna Kruschinski, PhD, Marina Konopleva, MD, PhD, Peter P. Ruvolo, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2454.
https://doi.org/10.1182/blood.V122.21.2454.2454
Published: 2013
Journal Articles

Proteomic Profiling of AML Bone Marrow-Derived Mesenchymal Stem Cells (MSC) Reveals Marked Differences From Normal MSC.

Rui-yu Wang, MD, PhD, Yi Hua Qiu, MD, Suk Young Yoo, PhD, Teresa McQueen, BS, Ye Chen, PhD, Zhihong Zeng, MD, Kevin R. Coombes, PhD, Wendy D. Schober, MLT (ASCP), Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2355.
https://doi.org/10.1182/blood.V120.21.2355.2355
Published: 2012
Journal Articles

Apoptosis Repressor with Caspase Recruitment Domain (ARC) Increases AML Cell Migration and Adhesion in Vitro and in Vivo by Regulating Leukemia-Stroma Interactions.

Bing Z Carter, Ph.D, Po Yee Mak, M.S., Ye Chen, PhD, Rodrigo Jacamo, Ph.D, Vivian Ruvolo, Duncan H Mak, M.S., Teresa McQueen, Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2626.
https://doi.org/10.1182/blood.V120.21.2626.2626
Published: 2012
Journal Articles

Leukemia Microenvironment and Pathologic Hypoxia: Sensitivity to Hypoxia-Activated Cytotoxin TH-302

Juliana M Benito, PhD, Volgin Y Andrei, Ye Chen, PhD, Lu Hongbo, Yuexi Shi, Teresa McQueen, Patrick A Zweidler-McKay, MD, PhD, Damian R Handisides, Charles Hart, Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1523.
https://doi.org/10.1182/blood.V120.21.1523.1523
Published: 2012
Journal Articles

The Hsa-Let-7a miRNA Enhances Ara-C Induced Apoptosis in Human Acute Myeloid Leukemia Cells

Ye Chen, PhD, Rodrigo Jacamo, Ph.D, Marina Konopleva, MD, PhD, Ramiro Garzon, MD, Carlo M. Croce, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1286.
https://doi.org/10.1182/blood.V120.21.1286.1286
Published: 2012
Journal Articles

Unique Effects of p53 −/− Leukemic Cells On Mesenchymal Stromal Cell Gene Expression Profile in Vitro

Xiaoyang Ling, PhD, Ye Chen, PhD, Peter P. Ruvolo, PhD, Vivian Ruvolo, Zhiqiang Wang, Ph.D., Min Zhang, Ph.D., Yuexi Shi, Marina Konopleva, MD, PhD, Richard E Davis, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3468.
https://doi.org/10.1182/blood.V120.21.3468.3468
Published: 2012
Journal Articles

NF-κB Activation in Mesenchymal Stromal Cells Mediates Leukemia Cell Chemoresistance

Rodrigo Jacamo, Ph.D, Ye Chen, PhD, Zhiqiang Wang, Ph.D., Wencai Ma, Ph.D., Min Zhang, Ph.D., Venkata L Battula, Ph.D., Wendy D. Schober, MLT (ASCP), Richard E Davis, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3518.
https://doi.org/10.1182/blood.V120.21.3518.3518
Published: 2012
Journal Articles

Targeting CXCR4, SDF1 and Beta-Adrenergic Receptors In the AML Microenvironment by Novel Antagonist POL6326, G-CSF and Isoproterenol

Ye Chen, PhD, Zhihong Zeng, PhD, Yuexi Shi, PhD, Rodrigo Jacamo, PhD, Christian Ludin, PhD, Klaus Dembowsky, PhD, Paul S. Frenette, MD, FRCPC, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2179.
https://doi.org/10.1182/blood.V116.21.2179.2179
Published: 2010