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Wafik S. El-Deiry, MD PhD
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Journal Articles

Potent Anti-Leukemic Effects of Small Molecule ONC212, a Member of the Imipridone Class of Anti-Cancer Compounds

Varun V Prabhu, PhD, Rohinton S Tarapore, PhD, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jessica M Wagner, Wafik S. El-Deiry, MD PhD, Martin Stogniew, PhD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD
Journal: Blood
Blood (2016) 128 (22): 5133.
https://doi.org/10.1182/blood.V128.22.5133.5133
Published: 2016
Journal Articles

Single Agent and Combinatorial Efficacy of First-in-Class Small Molecule ONC201 in Acute Leukemia and Multiple Myeloma

Varun V Prabhu, PhD, Amriti Lulla, Christina L Kline, PhD, Peter J Van den Heuvel, PhD, Mala K. Talekar, MD, Jessica M Wagner, Rohinton S Tarapore, PhD, David T Dicker, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD, Wafik S. El-Deiry, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2759.
https://doi.org/10.1182/blood.V128.22.2759.2759
Published: 2016
Journal Articles

ONC201 Possesses a Benign Safety Profile at Highly Efficacious Doses in Normal Human Cells and Animal Toxicology Studies

Joshua E. Allen, PhD, Jo Ishizawa, MD PhD, Wafik S. El-Deiry, MD PhD F.A.C.P, Michael Andreeff, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4812.
https://doi.org/10.1182/blood.V124.21.4812.4812
Published: 2014
Journal Articles

ONC201 Depletes Cancer Stem Cells in Refractory Cancer Patient Samples

Varun Vijay Prabhu, Jo Ishizawa, MD PhD, Dan Zhao, MD PhD, Joshua E. Allen, PhD, Tracy T. Batchelor, MD, Andrew S. Chi, MD PhD, Michael Andreeff, MD PhD, Wafik S. El-Deiry, MD PhD F.A.C.P
Journal: Blood
Blood (2014) 124 (21): 5219.
https://doi.org/10.1182/blood.V124.21.5219.5219
Published: 2014
Journal Articles

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Amriti R. Lulla, Christina Leah B Kline, PhD, Liz J. Hernandez-Borrero, Varun Vijay Prabhu, Jessica M Wagner, David T. Dicker, Nathan G. Dolloff, PhD, Brian M Barth, PhD, Jeffrey J Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5224.
https://doi.org/10.1182/blood.V124.21.5224.5224
Published: 2014
Journal Articles

Screen of Small Molecule ONC201/TIC10 Identifies Single Agent Activity and Combinatorial Efficacy with Bortezomib, Rituximab or Dexamethasone in Killing of Acute Lymphoblastic Leukemia Cells

Jessica M Wagner, Varun Vijay Prabhu, Leah L. Kline, PhD, Amriti R. Lulla, Liz J. Hernandez-Borrero, Jeffrey J. Pu, MD PhD, David T. Dicker, Brian M Barth, PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5233.
https://doi.org/10.1182/blood.V124.21.5233.5233
Published: 2014
Journal Articles

ONC201/TIC10 Is Effective As a Monoagent and Synergizes with Chemotherapy to Induce Cell Death in Non-Hodgkin Lymphoma

Mala K. Talekar, MD, Josh Allen, PhD, David T. Dicker, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5491.
https://doi.org/10.1182/blood.V124.21.5491.5491
Published: 2014
Journal Articles

Small Molecule ONC201/TIC10 Induces Caspase-Dependent Apoptosis in Acute Lymphoblastic Leukemia Cells Via Modulation of Bcl-2 and IAP Family Proteins

Varun Vijay Prabhu, Amriti R. Lulla, Jessica M Wagner, Liz J. Hernandez-Borrero, Mala K. Talekar, MD, Christina L. Kline, PhD, David T. Dicker, Brian M Barth, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5237.
https://doi.org/10.1182/blood.V124.21.5237.5237
Published: 2014
Journal Articles

Synergistic Effect of Quinacrine with Chemotherapeutics or TRAIL in Hematopoietic Malignant Cells

Wenge Wang, MD PhD, Amriti R. Lulla, Liz J. Hernandez-Borrero, David T. Dicker, Emmanuel K. Teye, Mala K. Talekar, MD, Nathan G. Dolloff, PhD, Jeffrey J. Pu, MD PhD, Wafik S. El-Deiry, MD PhD
Journal: Blood
Blood (2014) 124 (21): 5239.
https://doi.org/10.1182/blood.V124.21.5239.5239
Published: 2014