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Violetta Leshchenko, PhD
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Journal Articles

Aberrant Cell Cycle Programming Confers Rapid Lethality in the EuSOX11+ CCND1 MCL Mouse Model

Donna R Edwards, MPH, PhD, Pei-yu Kuo, MS, Alessandro Lagana, PhD, Seongjee Park, Pavithra Nedumaran, MS, Violetta Leshchenko, PhD, Stephanie Christie, PhD, Shashidhar Jatiani, PhD, Julie Teruya-Feldstein, MD, Samir Parekh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-143038
Published: 2020
Journal Articles

ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes

Rafail Nikolaos Tasakis, MSc, BSc, Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Jonathan J Keats, PhD, Daniel Auclair, Deepu Madduri, MD, Joshua Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, F. Nina Papavasiliou, PhD, Samir Parekh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3092.
https://doi.org/10.1182/blood-2019-130669
Published: 2019
Journal Articles

A Machine Learning Approach Identifies a 30-Gene Model That Predicts Sensitivity to Selinexor in Multiple Myeloma

Alessandro Lagana, PhD, Sherry Bhalla, Adolfo Aleman, Anna Huo-Chang Mei, MS, Violetta Leshchenko, PhD, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepu Madduri, MD, Joshua R Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3101.
https://doi.org/10.1182/blood-2019-130753
Published: 2019
Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3216.
https://doi.org/10.1182/blood-2018-99-116500
Published: 2018
Journal Articles

Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma

Alessandro Lagana, PhD, Dan Fu Ruan, David Melnekoff, BS,MS, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Adeeb Rahman, Seunghee Kim-Schultze, PhD, Ying Song, Jonathan J Keats, PhD, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Amir Horowitz, PhD, Samir Parekh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 59.
https://doi.org/10.1182/blood-2018-99-116828
Published: 2018
Journal Articles

Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project

Alessandro Lagana, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Jonathan J. Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 325.
https://doi.org/10.1182/blood.V130.Suppl_1.325.325
Published: 2017
Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine

David Melnekoff, BS, MSc, Alessandro Lagana, PhD, Wissam Hamou, PhD, Kimaada Allette, BS, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Robert Sebra, PhD, Samir Parekh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 62.
https://doi.org/10.1182/blood.V130.Suppl_1.62.62
Published: 2017
Journal Articles

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Deepak Perumal, PhD, Jonathan Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 268.
https://doi.org/10.1182/blood.V130.Suppl_1.268.268
Published: 2017
Journal Articles

MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA

Hearn Jay Cho, MD PhD, Anna Huo-Chang Mei, MS, Jami Fukui, MD, Kaity Tung, BS, Deepak Perumal, PhD, Violetta Leshchenko, PhD, Alessandro Lagana, PhD, Seunghee Kim-Schultze, PhD, Ajai Chari, Sundar Jagannath, MD, Samir Parekh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4332.
https://doi.org/10.1182/blood.V130.Suppl_1.4332.4332
Published: 2017
Journal Articles

Inhibiting SOX11-DNA Interaction in Mantle Cell Lymphoma

Stephanie Christie, Shashidhar Jatiani, PhD, Pei-Yu Kuo, MS, Violetta Leshchenko, PhD, Abhijeet Kapoor, PhD, Paola Bisignano, PhD, Aneel Aggarwal, PhD, Marta Filizola, PhD, Samir Parekh, MD
Journal: Blood
Blood (2016) 128 (22): 1840.
https://doi.org/10.1182/blood.V128.22.1840.1840
Published: 2016
Journal Articles

Genome-Wide Methylation Analysis of Primary Mantle Cell Lymphomas Identifies Novel Gene Targets for Epigenetic Drug Therapy.

Violetta Leshchenko, PhD, Pei-Yu Kuo, MS, Rita Shaknovich, MD, PhD, Tobias Gellen, Yvonne Remache, BS, Marc Weniger, PhD, K. Stephen Suh, PhD, Andre Goy, MD, Wyndham Wilson, MD, PhD, Ira Braunschweig, MD, Amit Verma, MD, Adrian Wiestner, MD, PhD, Ari Melnick, MD, Samir Parekh, MD
Journal: Blood
Blood (2009) 114 (22): 673.
https://doi.org/10.1182/blood.V114.22.673.673
Published: 2009