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Victoria J Weston, PhD
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Journal Articles

The Sub-Clonal Complexity of STIL-TAL1 T-ALL

Caroline L Furness, MD, Marcela B Mansur, PhD, Victoria J Weston, PhD, Sarah Jenkinson, MSc, Frederik W van Delft, MDPhD, Lyndal Kearney, PhD, Ian Titley, PhD, Anthony M Ford, PhD, Rosemary E Gale, Pamela R Kearns, MBChB, PhD FRCPCH, Adolfo A. Ferrando, MD PhD, Christine J. Harrison, Nicola E Potter, PhD, Mel Greaves, FRS
Journal: Blood
Blood (2014) 124 (21): 3788.
https://doi.org/10.1182/blood.V124.21.3788.3788
Published: 2014
Journal Articles

Clonal Evolution and Sub-Clonal Architecture In Paediatric T-Cell Acute Lymphoblastic Leukaemia (T-ALL)

Caroline L Furness, MD, Marcela B Mansur, PhD, Victoria J Weston, PhD, Frederik W Van Delft, MD PhD, Christine J Harrison, PhD, Lyndal Kearney, PhD, Anthony M Ford, PhD, Pamela R Kearns, MBChB, PhD, FRCPCH, Nicola E Potter, PhD, Jean Soulier, MD, PhD, Adolfo A. Ferrando, MD, PhD, Mel Greaves, PhD, FRS
Journal: Blood
Blood (2013) 122 (21): 1366.
https://doi.org/10.1182/blood.V122.21.1366.1366
Published: 2013
Journal Articles

An Analysis Of Mechanisms Of Central Nervous System Infiltration In Acute Lymphoblastic Leukaemia Using Primary Cells Xenografted Into Immunodeficient Mice

Yasar M Yousafzai, MBBS, Mark TS Williams, PhD, Klaus Rehe, MD, Michelle Le Brocq, PhD, Simon Bomken, MBBS, PhD, Paul B Sinclair, PhD, Katie Dormon, MSc, Dino Masic, MRes, Leanne Archer, B.Sc, Jennifer Watt, BSc, Tracey A Perry, BSc, Victoria J Weston, PhD, Pamela R Kearns, MBChB, PhD, FRCPCH, Helen Blair, PhD, Russel Lisa, PhD, Olaf Heidenreich, PhD, Julie Irving, PhD, Josef Vormoor, MD, Brenda Gibson, MD, Gerard J Graham, PhD, Christina Halsey, PhD, FRCPath
Journal: Blood
Blood (2013) 122 (21): 3866.
https://doi.org/10.1182/blood.V122.21.3866.3866
Published: 2013
Journal Articles

Inhibition of BRD4 Bromodomains Is a Potent Novel Strategy to Target Apoptosis Resistance in Paediatric ALL

David Da Costa, Victoria J Weston, PhD, Wenbin Wei, PhD, Angelo Agathanggelou, PhD, Eva Petermann, PhD, Stefan Knapp, PhD, Pamela R Kearns, BSc, MBBCh, MRCP, PhD, Tatjana Stankovic, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 77.
https://doi.org/10.1182/blood.V118.21.77.77
Published: 2011
Journal Articles

Insight Into T-ALL Leukaemia Initiating Cells, Clonal Evolution and Impact of Treatment In Vivo Using Immune-Compromised Mouse Model,

Victoria J Weston, PhD, Tracey A Perry, BSc, Helen Roberts, BSc, Katie Brown, Shaun R Wilson, MBChB, MRCPCH, Pamela R Kearns, BSc, MBBCh, MRCP, PhD
Journal: Blood
Blood (2011) 118 (21): 3577.
https://doi.org/10.1182/blood.V118.21.3577.3577
Published: 2011
Journal Articles

Characterisation of Leukaemic Stem Cell Populations in Childhood AML Indicate Distinct Disease Subtypes with Diverse Clinical Features

Victoria J Weston, PhD, Tracey A Perry, BSc, Katie Brown, Shaun R Wilson, MBChB, MRCPCH, Pamela R Kearns, BSc, MBBCh, MRCP, PhD
Journal: Blood
Blood (2011) 118 (21): 1500.
https://doi.org/10.1182/blood.V118.21.1500.1500
Published: 2011
Journal Articles

Tyrosine Kinase Inhibitor Screen Identifies the Multikinase Inhibitor, Foretinib, As a Sensitisor of Treatment-resistant B-Precursor ALL to Core Chemotherapeutic Agents

Shaun R Wilson, MBChB, MRCPCH, Victoria J Weston, PhD, Tatjana Stankovic, MD, PhD, Pamela R Kearns, BSc, MBBCh, MRCP, PhD
Journal: Blood
Blood (2011) 118 (21): 1509.
https://doi.org/10.1182/blood.V118.21.1509.1509
Published: 2011
Journal Articles

CLL Xenograft Models to Address the Impact of Single Gene Loss (ATM) on Proliferation and Cytotoxic Response

Ceri E Oldreive, PhD, Victoria J Weston, PhD, Paul AH Moss, MD, PhD, Guy Pratt, Pamela R. Kearns, BSc, MBBCh, MRCP, PhD, A. Malcolm R Taylor, PhD, Tatjana Stankovic, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2439.
https://doi.org/10.1182/blood.V116.21.2439.2439
Published: 2010
Journal Articles

The PIM Kinase Inhibitor K00135 Sensitizes Primary Acute Lymphoblastic Leukaemia (ALL) Cells to DNA-Damaging Agents

David Da Costa, Victoria J Weston, PhD, Stefan Knapp, PhD, A. Malcolm R Taylor, PhD, Pamela R. Kearns, BSc, MBBCh, MRCP, PhD, Tatjana Stankovic, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3238.
https://doi.org/10.1182/blood.V116.21.3238.3238
Published: 2010
Journal Articles

ATM Mutant Lymphoid Tumour Cells Exhibit Impaired Activation of the Redox-Sensitive Nrf2-ARE Detoxification Pathway and Are Differentially Sensitive to Nrf2-Activating Compounds

Victoria J Weston, PhD, Angelo Agathanggelou, PhD, Paul AH Moss, MD, PhD, Pamela R. Kearns, BSc, MBBCh, MRCP, PhD, A. Malcolm R Taylor, PhD, Tatjana Stankovic, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 49.
https://doi.org/10.1182/blood.V116.21.49.49
Published: 2010