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Journal Articles

Is glutamine depletion needed in ALL disease?

Vassilios I. Avramis

Blood (2014) 123 (23): 3532–3533.

https://doi.org/10.1182/blood-2014-04-565523

Published: 2014

Journal Articles

High-Grade Pegylated Asparaginase-Related Hepatotoxicity Occurrence In a Pediatric-Inspired Adult Acute Lymphoblastic Leukemia Regimen Does Not Necessarily Predict Recurrent Hepatotoxicity In Subsequent Cycles

Patrick W. Burke, MD, Ibrahim Aldoss, MD, Matthew A. Lunning, DO, Vassilios I. Avramis, PhD, Ann M. Mohrbacher, MD, Vinod Pullarkat, MD, Martin S. Tallman, MD, Dan Douer, MD

Blood (2013) 122 (21): 2671.

https://doi.org/10.1182/blood.V122.21.2671.2671

Published: 2013

Journal Articles

Adverse Reactions to PEG and Erwinia Asparaginase and Correlation with Anti-Asparaginase Antibody Data and Survival in Children with Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group Study CCG 1961.

Girish Dhall, M.D., Tamekia Jones, PhD, David Radvinsky, Nathan Robison, MD, Anna Butturini, MD, Joan I Rubin, RN, Paul S. Gaynon, MD, Eduard H Panosyan, MD, Ioannis A Avramis, Vassilios I Avramis, PhD, Lawrence J. Ettinger, MD, Nita L. Seibel, MD

Blood (2009) 114 (22): 3077.

https://doi.org/10.1182/blood.V114.22.3077.3077

Published: 2009

Journal Articles

Sustained and Prolonged Asparagine Depletion by Multiple Doses of Intravenous Pegylated Asparaginase in the Treatment of Adults with Newly Diagnosed Acute Lymphoblastic Leukemia.

Dan Douer, Kristy Watkins, Lisa Mark, Mohrbacher Ann, Allen S Yang, Vassilios I Avramis

Blood (2008) 112 (11): 1928.

https://doi.org/10.1182/blood.V112.11.1928.1928

Published: 2008

Journal Articles

Obesity Alters the Pharmacokinetics of Vincristine in Mice.

James W Behan, Vassilios I Avramis, PhD, Jason P Yun, Anna Butturini, MD, Steven D Mittelman, MD, PhD

Blood (2008) 112 (11): 1636.

https://doi.org/10.1182/blood.V112.11.1636.1636

Published: 2008

Journal Articles

Failure of Asparagine (ASN) Depletion, Not Inadequate Asparaginase (ASNase) Activity, Predicts Relapse in Standard Risk (SR) Childhood Acute Lymphoblastic Leukemia (ALL): A Children’s Oncology Group (COG) Report.

Vassilios I. Avramis, PhD, John S. Holcenberg, MD, Alice G. Ettinger, RN, Linda C. Stork, MD, Mei La, MS, Paul S. Gaynon, MD

Blood (2007) 110 (11): 588.

https://doi.org/10.1182/blood.V110.11.588.588

Published: 2007

Journal Articles

Pharmacodynamics and safety of intravenous pegaspargase during remission induction in adults aged 55 years or younger with newly diagnosed acute lymphoblastic leukemia

Dan Douer, Henry Yampolsky, Lewis J. Cohen, Kristy Watkins, Alexandra M. Levine, Antonia P. Periclou, Vassilios I. Avramis

Blood (2006) 109 (7): 2744–2750.

https://doi.org/10.1182/blood-2006-07-035006

Published: 2006

Journal Articles

Assessment of Anti-Asparaginase (ASNase) Antibodies (Ab) and ASNase Activity after Suspected Clinical Allergy.

Prakash N. Tiwari, MD, Monica Zielinski, MS, John J. Quinn, MD, Stuart E. Siegel, MD, Paul S. Gaynon, MD, Peter Wakamatsu, MPH, Nita L. Seibel, MD, Vassilios I. Avramis, PhD

Blood (2006) 108 (11): 1878.

https://doi.org/10.1182/blood.V108.11.1878.1878

Published: 2006

Journal Articles

A Phase I Study of Oral 6-Thioguanine, Followed by Continuous Infusion Cytarabine, Followed by Intramuscular PEG-Asparaginase (“TGAP”) in Children with Relapsed or Refractory Acute Leukemia or Non-Hodgkin’s Lymphoma.

Cecilia H. Fu, MD, Janet L. Franklin, MD, Paul Gaynon, MD, Colleen McCarthy, RN, Edward Panosyan, MD, Stuart E. Siegel, MD, Vassilios I. Avramis, MD

Blood (2006) 108 (11): 4536.

https://doi.org/10.1182/blood.V108.11.4536.4536

Published: 2006

Journal Articles

Pharmacokinetics and Pharmacodynamics of Three Asparaginases in Pediatric Patients with Higher Risk Acute Lymphoblastic Leukemia: A Report from CCG-1961.

Eduard H. Panosyan, M.D., Nita L. Seibel, M.D., Rita S. Grigoryan, M.D., Ioannis A. Avramis, B.S., Jon D. Jaques, Lawrence J. Ettinger, M.D., Paul S. Gaynon, M.D., Harland N. Sather, Ph.D., Janet Franklin, M.D., Fu Cecilia, M.D., Stuart E. Siegel, M.D., Howard J. Fingert, M.D., Vassilios I. Avramis, Ph.D.

Blood (2004) 104 (11): 2745.

https://doi.org/10.1182/blood.V104.11.2745.2745

Published: 2004

Journal Articles

Pharmacodynamic (PD) Analyses of Asparagine (Asn) Deamination and Asn Input (Imax) in Serum of Pediatric Patients with Standard Risk Acute Lymphoblastic Leukemia (SR ALL) Receiving Native or Pegylated E. Coli Asparaginases (ASNase) (CCG-1962).

Vassilios I. Avramis, Ph.D., Eduard H. Panosyan, M.D., Cecilia H. Fu, M.D., Linda C. Stork, M.D., Paul S. Gaynon, M.D.

Blood (2004) 104 (11): 2082.

https://doi.org/10.1182/blood.V104.11.2082.2082

Published: 2004

Journal Articles

A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study

Vassilios I. Avramis, Susan Sencer, Antonia P. Periclou, Harland Sather, Bruce C. Bostrom, Lewis J. Cohen, Alice G. Ettinger, Lawrence J. Ettinger, Janet Franklin, Paul S. Gaynon, Joanne M. Hilden, Beverly Lange, Fataneh Majlessipour, Pracad Mathew, Michael Needle, Joseph Neglia, Gregory Reaman, John S. Holcenberg

Blood (2002) 99 (6): 1986–1994.

https://doi.org/10.1182/blood.V99.6.1986

Published: 2002

NARROW

Is glutamine depletion needed in ALL disease?

High-Grade Pegylated Asparaginase-Related Hepatotoxicity Occurrence In a Pediatric-Inspired Adult Acute Lymphoblastic Leukemia Regimen Does Not Necessarily Predict Recurrent Hepatotoxicity In Subsequent Cycles

Adverse Reactions to PEG and Erwinia Asparaginase and Correlation with Anti-Asparaginase Antibody Data and Survival in Children with Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group Study CCG 1961.

Sustained and Prolonged Asparagine Depletion by Multiple Doses of Intravenous Pegylated Asparaginase in the Treatment of Adults with Newly Diagnosed Acute Lymphoblastic Leukemia.

Obesity Alters the Pharmacokinetics of Vincristine in Mice.

Failure of Asparagine (ASN) Depletion, Not Inadequate Asparaginase (ASNase) Activity, Predicts Relapse in Standard Risk (SR) Childhood Acute Lymphoblastic Leukemia (ALL): A Children’s Oncology Group (COG) Report.

Pharmacodynamics and safety of intravenous pegaspargase during remission induction in adults aged 55 years or younger with newly diagnosed acute lymphoblastic leukemia

Assessment of Anti-Asparaginase (ASNase) Antibodies (Ab) and ASNase Activity after Suspected Clinical Allergy.

A Phase I Study of Oral 6-Thioguanine, Followed by Continuous Infusion Cytarabine, Followed by Intramuscular PEG-Asparaginase (“TGAP”) in Children with Relapsed or Refractory Acute Leukemia or Non-Hodgkin’s Lymphoma.

Pharmacokinetics and Pharmacodynamics of Three Asparaginases in Pediatric Patients with Higher Risk Acute Lymphoblastic Leukemia: A Report from CCG-1961.

Pharmacodynamic (PD) Analyses of Asparagine (Asn) Deamination and Asn Input (Imax) in Serum of Pediatric Patients with Standard Risk Acute Lymphoblastic Leukemia (SR ALL) Receiving Native or Pegylated E. Coli Asparaginases (ASNase) (CCG-1962).

A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study

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American Society of Hematology

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American Society of Hematology

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