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Valder R. Arruda, M.D., Ph.D.
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Journal Articles

Successful Long Term Therapeutic Expression of Factor VIII in Hemophilia A Dogs After Administration of AAV-cFVIII Using a Two-Chain or Single Chain Delivery Approach.

Denise E. Sabatino, Ph.D., Ekaterina Altynova, B.S., Amy M. Lange, B.S., Shangzhen Zhou, M.D., Elizabeth P. Merricks, B.S., Aaron M. Dillow, B.S., Timothy C. Nichols, M.D., Valder R. Arruda, M.D., Ph.D., Haig H. Kazazian, Jr., M.D.
Journal: Blood
Blood (2009) 114 (22): 546.
https://doi.org/10.1182/blood.V114.22.546.546
Published: 2009
Journal Articles

FIX-R338L (FIX Padua) as a Successful Alternative for the Treatment of Canine Severe Hemophilia B.

Jonathan D Finn, PhD, Paolo Simioni, MD, PhD, Nicholas Iacobelli, B.Sc., Shangzhen Zhou, Timothy C. Nichols, MD, Katherine A. High, MD, Valder R. Arruda, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 694.
https://doi.org/10.1182/blood.V114.22.694.694
Published: 2009
Journal Articles

Zymogen-Like Factor Xa Variants Restore Thrombin Generation and Effectively Bypass the Intrinsic Pathway in Vitro

Matthew W Bunce, Ph.D., Raffaella Toso, Ph.D., Valder R. Arruda, M.D., Ph.D., Rodney M. Camire, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 240.
https://doi.org/10.1182/blood.V112.11.240.240
Published: 2008
Journal Articles

Factor Xa Variants as Novel Bypass Agents for the Treatment of Hemophilia in Murine Models

Lacramioara Ivanciu, Ph.D., Raffaella Toso, Ph.D., Alexander Schlachterman, M.D., Harre Downey, B.S., Jian-Hua Liu, B.S., Valder R. Arruda, M.D., Ph.D., Rodney M. Camire, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 239.
https://doi.org/10.1182/blood.V112.11.239.239
Published: 2008
Journal Articles

Induction of Immune Tolerance to Canine FVIII in Hemophilia a Dogs with Inhibitors Using AAV-Mediated Expression of Canine FVIII

Jonathan D Finn, PhD, Denise E Sabatino, PhD, Margareth C Ozelo, MD, Shangzhen Zhou, MD, David Lillicrap, MD, Haig H Kazazian, MD, Timothy C. Nichols, MD, Valder R. Arruda, M.D., Ph.D.
Journal: Blood
Blood (2008) 112 (11): 243.
https://doi.org/10.1182/blood.V112.11.243.243
Published: 2008
Journal Articles

Assessing Hemostatic Efficacy of Continuous Expression of Factor VIIa Following Administration of AAV Vectors into Hemophilia B Mice.

Alexander Schlachterman, B.A., Jianhua Liu, Majed Aljamali, Ph.D., Valder R. Arruda, M.D., Ph.D., Katherine A. High, M.D.
Journal: Blood
Blood (2004) 104 (11): 3184.
https://doi.org/10.1182/blood.V104.11.3184.3184
Published: 2004