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Journal Articles

Safety, Efficacy, and Determination of the Recommended Phase 2 Dose for the Oral Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330)

Christine Chen, MD, Ramiro Garzon, MD, Martin Gutierrez, Meagan A. Jacoby, MD PhD, Peter Brown, Ian Flinn, Richard M. Stone, MD, Mary Lynn Savoie, MD, Rachid Baz, Nashat Y. Gabrail, MD, Michael Wang, MD, Peter Martin, MD, David Siegel, MD PhD, Morten Mau-Sørensen, Michael Andreef, Tracey Marshall, Jean-Richard Saint-Martin, Robert Carlson, Sharon Shacham, Michael Kauffman, John Kuruvilla, MD
Journal: Blood
Blood (2015) 126 (23): 258.
https://doi.org/10.1182/blood.V126.23.258.258
Published: 2015
Journal Articles

Selinexor Demonstrates Marked Synergy with Dexamethasone (Sel-Dex) in Preclinical Models and in Patients with Heavily Pretreated Refractory Multiple Myeloma (MM)

Christine I. Chen, MD MD FRCPC, Martin Gutierrez, MD, David S. Siegel, MD PhD, Joshua R. Richter, MD, Nina Wagner-Johnston, Craig C Hofmeister, MD MPH, Jesus G. Berdeja, MD, Nashat Gabrail, MD, Rachid Baz, MD, Morten Mau-Sorensen, MD, Suzanne Trudel, MD MSC, FRCPC, Rodger E. Tiedemann, MD PhD, Vishal Kukreti, MD, Nuchanan Areethamsirikul, MD, Asfar Azmi, PhD, Trinayan Kashyap, MSc, Yosef Landesman, PhD, Tracey Marshall, John McCartney, PhD, Jean-Richard Saint-Martin, Sasha Norori, MSc, Michael R Savona, MD, Tami Rashal, MD, Robert Carlson, PhD, Mansoor R Mirza, MD, Sharon Shacham, PhDMBA, Michael Kauffman, MD PhD, Donna E Reece, MD FRCPC
Journal: Blood
Blood (2014) 124 (21): 4773.
https://doi.org/10.1182/blood.V124.21.4773.4773
Published: 2014
Journal Articles

The Oral Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) Demonstrates Broad and Durable Clinical Activity in Relapsed / Refractory Non Hodgkin’s Lymphoma (NHL)

John Kuruvilla, MD, John C. Byrd, MD, Joseph M Flynn, Ramiro Garzon, MD, Pierluigi Porcu, MD, Nina Wagner-Johnston, Mary Lynn Savoie, MD FRCPC, Richard M. Stone, MD, Eric D. Jacobsen, MD, Morten Mau-Sorensen, MD, Peter de Nully Brown, Rachid Baz, MD, Bijal Shal, MD, Ian Flinn, Nashat Gabrail, MD, Vishal Kukreti, MD, Rodger E. Tiedemann, MD PhD, Yosef Landesman, PhD, Boris Klebanov, M.A., MsC, Eran Shacham, PhD, Jean-Richard Saint-Martin, Tracey Marshall, John McCartney, PhD, Dilara McCauley, PhD, Robert Carlson, PhD, Sasha Norori, MSc, Michael R Savona, MD, Tami Rashal, MD, Mansoor R Mirza, MD, Michael Kauffman, MD PhD, Sharon Shacham, PhD MBA
Journal: Blood
Blood (2014) 124 (21): 396.
https://doi.org/10.1182/blood.V124.21.396.396
Published: 2014