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Journal Articles

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Blood (2019) 134 (Supplement_1): 2525.

https://doi.org/10.1182/blood-2019-126663

Published: 2019

Journal Articles

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

Goichi Tatsumi, MD, Masahiro Kawahara, MD PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Ryusuke Yamamoto, MD, Masakatsu Hishizawa, MD PhD, Toshiya Inaba, MD PhD, Takayoshi Suzuki, PhD, Akira Andoh, MD PhD, Akifumi Kondo Takaori, MD PhD

Blood (2017) 130 (Supplement 1): 3797.

https://doi.org/10.1182/blood.V130.Suppl_1.3797.3797

Published: 2017

Journal Articles

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Yuichiro Nakata, PhD, Norimasa Yamasaki, Takeshi Ueda, MD, PhD, Kenichiro Ikeda, MD, Akiko Nagamachi, PhD, Toshiya Inaba, MD, PhD, Hiroaki Honda, MD, PhD

Blood (2016) 128 (22): 2653.

https://doi.org/10.1182/blood.V128.22.2653.2653

Published: 2016

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Hirotaka Matsui, MD, PhD, Akiko Nagamachi, Akinori Kanai, PhD, Yuko Ozaki, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2013) 122 (21): 227.

https://doi.org/10.1182/blood.V122.21.227.227

Published: 2013

Journal Articles

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

Yoshiyuki Kobayashi, MD, Hirotaka Matsui, MD, Akinori Kanai, PhD, Miyuki Tsumura, MSc, Satoshi Okada, MD, PhD, Mizuka Miki, MD, Kazuhiro Nakamura, MD, PhD, Shinji Kunishima, PhD, Toshiya Inaba, MD, PhD, Masao Kobayashi, MD, PhD

Blood (2012) 120 (21): 1081.

https://doi.org/10.1182/blood.V120.21.1081.1081

Published: 2012

Journal Articles

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

Chizuru Saito, MD, Kohei Hosokawa, MD, Takamasa Katagiri, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD, Toshiya Inaba, MD, PhD, Masafumi Taniwaki, MD, PhD, Hirohito Yamazaki, MD, PhD, Shinji Nakao, MD, PhD

Blood (2012) 120 (21): 645.

https://doi.org/10.1182/blood.V120.21.645.645

Published: 2012

Journal Articles

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Hirotaka Matsui, MD, Yuko Ozaki, Akiko Nagamachi, Toshiya Inaba, MD, PhD

Blood (2012) 120 (21): 1297.

https://doi.org/10.1182/blood.V120.21.1297.1297

Published: 2012

Journal Articles

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, PhD, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2011) 118 (21): 869.

https://doi.org/10.1182/blood.V118.21.869.869

Published: 2011

Journal Articles

The Anti-Proliferative Effects of Tricyclic Coumarin GUT-70 as An Hsp90 Inhibitor In Mantle Cell Lymphoma

Linhua Jin, PhD, Shinya Kimura, MD, PhD, Yixin Zhou, Junya Kuroda, MD, PhD, Hiroya Asou, MD, PhD, Toshiya Inaba, MD, PhD, Takashi Miida, MD, PhD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Yoko Tabe, MD, PhD

Blood (2010) 116 (21): 3977.

https://doi.org/10.1182/blood.V116.21.3977.3977

Published: 2010

Journal Articles

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2010) 116 (21): 4170.

https://doi.org/10.1182/blood.V116.21.4170.4170

Published: 2010

Journal Articles

The Tricyclic Coumarin GUT-70 Induces Apoptosis and Cell Cycle Arrest Preferentially in Mantle Cell Lymphomas with Mutant p53.

Linhua Jin, PhD, Shinya Kimura, MD, PhD, Yixin Zhou, Junya Kuroda, MD, PhD, Hiroya Asou, MD, Toshiya Inaba, MD, Michael Andreeff, MD, PhD, Takashi Miida, MD, PhD, Yoko Tabe, MD, PhD

Blood (2009) 114 (22): 1684.

https://doi.org/10.1182/blood.V114.22.1684.1684

Published: 2009

Journal Articles

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Daisuke Aki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2009) 114 (22): 2963.

https://doi.org/10.1182/blood.V114.22.2963.2963

Published: 2009

Journal Articles

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

Akiko Nagamachi, Hiroya Asou, MD, Hirotaka Matsui, MD, Yuko Ozaki, Daisuke Aki, PhD, Kazuko Miyazaki, Norimasa Yamasaki, Masaki Miyazaki, MD, Linda Wolff, PhD, Richard Koller, Hideaki Oda, MD, Toshiya Inaba, MD, Hiroaki Honda, MD

Blood (2008) 112 (11): 197.

https://doi.org/10.1182/blood.V112.11.197.197

Published: 2008

Journal Articles

Identification of Two 7q Genes Encoding Centrosomal Proteins as Myeloid Tumor-Suppressor Candidates.

Hiroya Asou, Yuko Ozaki, Akiko Nagamachi, Daisuke Aki, Hirotaka Matsui, Toshiya Inaba, MD

Blood (2008) 112 (11): 1793.

https://doi.org/10.1182/blood.V112.11.1793.1793

Published: 2008

Journal Articles

Downregulation of a Candidate Myeloid Tumor Suppressor Gene Isolated from 7q21 Induces Abnormal Mitosis Due to Insufficient Centrosome Maturation.

Hiroya Asou, MD, Hirotaka Matsui, MD, Yuko Ozaki, Akiko Nagamachi, Daisuke Aki, PhD, Miho Ohsugi, PhD, Toshiya Inaba, MD

Blood (2007) 110 (11): 2638.

https://doi.org/10.1182/blood.V110.11.2638.2638

Published: 2007

Journal Articles

Induction of CD33 Expression in B-Precursor ALL by E2A-HLF Fusion Transcription Factor Derived from t(17;19).

Koshi Akahane, MD, Takeshi Inukai, MD, Toshiya Inaba, MD, Hidemitsu Kurosawa, MD, Mikiya Endo, MD, Hiroaki Goto, MD, Nobutaka Kiyokawa, MD, A. Thomas Look, MD, Kumiko Goi, MD, Kanji Sugita, MD, Shinpei Nakazawa, MD

Blood (2005) 106 (11): 851.

https://doi.org/10.1182/blood.V106.11.851.851

Published: 2005

Journal Articles

Regulation of mRNA Stability by Heat Shock Cognate Protein 70 (Hsc70) under the Control of Cytokines.

Hirotaka Matsui, MD, Toshiya Inaba, MD

Blood (2004) 104 (11): 36.

https://doi.org/10.1182/blood.V104.11.36.36

Published: 2004

NARROW

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

The Anti-Proliferative Effects of Tricyclic Coumarin GUT-70 as An Hsp90 Inhibitor In Mantle Cell Lymphoma

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

The Tricyclic Coumarin GUT-70 Induces Apoptosis and Cell Cycle Arrest Preferentially in Mantle Cell Lymphomas with Mutant p53.

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

Identification of Two 7q Genes Encoding Centrosomal Proteins as Myeloid Tumor-Suppressor Candidates.

Downregulation of a Candidate Myeloid Tumor Suppressor Gene Isolated from 7q21 Induces Abnormal Mitosis Due to Insufficient Centrosome Maturation.

Induction of CD33 Expression in B-Precursor ALL by E2A-HLF Fusion Transcription Factor Derived from t(17;19).

Regulation of mRNA Stability by Heat Shock Cognate Protein 70 (Hsc70) under the Control of Cytokines.

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American Society of Hematology

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American Society of Hematology

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