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Thiago Maciel, PhD
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Journal Articles

A Novel, Highly Potent and Selective PDE9 Inhibitor for the Treatment of Sickle Cell Disease

James G McArthur, PhD, Thiago Maciel, PhD, Chunsheng Chen, PhD, Aurelie Fricot, Dione Kobayashi, PhD, Julia Nguyen, BS, Phong Nguyen, Anna Parachova, PhD, Fuad Abdulla, Gregory M. Vercellotti, MD, Niels Svenstrup, PhD, John D Belcher, PhD
Journal: Blood
Blood (2016) 128 (22): 268.
https://doi.org/10.1182/blood.V128.22.268.268
Published: 2016
Journal Articles

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Tenzin Choesang, Huihui Li, MS, Michael Dussiot, Thiago Maciel, PhD, Laura Breda, PhD, Daniel Garcia Santos, PhD, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Ivan Cruz Moura, PhD, Prem Ponka, MD PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2014) 124 (21): 4037.
https://doi.org/10.1182/blood.V124.21.4037.4037
Published: 2014
Journal Articles

Modulation of Activin Signaling by RAP-011 (ActRIIA-IgG1) Improve Anemia, Increases Hemoglobin Levels and Corrects Ineffective Erythropoiesis in β-Thalassemia

Michael Dussiot, Thiago Maciel, PhD, Aurelie Fricot, Joel Veiga, Etienne Paubelle, Emmanuel Payen, Yves Beuzard, MD, Jean-Antoine Ribeil, MD, PhD, Jean-Benoît Arlet, MD, Genevieve Courtois, PhD, Tom O Daniel, MD, PhD, Rajesh Chopra, MD, PhD, Victoria Sung, Ph.D., Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD
Journal: Blood
Blood (2012) 120 (21): 247.
https://doi.org/10.1182/blood.V120.21.247.247
Published: 2012
Journal Articles

Heat Shock Protein 70 Cytosolic Sequestration by Excess of Free Alpha-Globin Chains Is a Key Mechanism of the Ineffective Erythropoiesis in β-Thalassemia Major Patients

Jean-Benoît Arlet, MD, Jean-Antoine Ribeil, MD, PhD, Adonis Hazoumé, PhD, Samuel Demarest, Luba Tchertanov, PhD, Dussiot Michael, Ivan Cruz Moura, PhD, Thiago Maciel, PhD, Christian Auclair, PhD, Olivier Negre, PhD, Philippe Leboulch, MD, Véronique Baudin-creuza, PhD, Carmen Garrido, PhD, Genevieve Courtois, PhD, Olivier Hermine, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 823.
https://doi.org/10.1182/blood.V120.21.823.823
Published: 2012
Journal Articles

Polymeric Immunoglobulin A1 Controls Erythroblast Proliferation and Accelerates Erythropoiesis Recovery in Anemia

Séverine Coulon, PharmD PhD, Michael Dussiot, Damien Grapton, Thiago Maciel, PhD, Pamella Huey Mei Wang, PhD, Celine Callens, PharmD PhD, Bertrand Arnulf, MD, PhD, Patrick Mayeux, Benhamou Marc, Michel Cogné, MD, PhD, Renato Monteiro, MD, PhD, Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD
Journal: Blood
Blood (2011) 118 (21): 679.
https://doi.org/10.1182/blood.V118.21.679.679
Published: 2011