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Journal Articles

Machine Learning-Based Flow Cytometry Diagnostics in Myelodysplastic Syndromes: Validation in the HOVON89 Clinical Trial (EudraCT 2008-002195-10)

Carolien Duetz, MD, Sofie Van Gassen, PhD, Theresia M. Westers, PhD, Florentien in t Hout, MDPhD, Eline Cremers, MDPhD, Canan Alhan, MD PhD, Costa Bachas, PhD, Margot F. Van Spronsen, MD, Heleen Visser-Wisselaar, Dana Chitu, Aniek O. De Graaf, PhD, Joop Jansen, PhD, Yvan Saeys, PhD, Arjan van de Loosdrecht, MD PhD

Blood (2020) 136 (Supplement 1): 10–12.

https://doi.org/10.1182/blood-2020-136719

Published: 2020

Journal Articles

Durable Responses and Survival in High Risk AML and MDS Patients Treated with an Allogeneic Leukemia-Derived Dendritic Cell Vaccine

Luca L.G. Janssen, MD, Theresia M. Westers, PhD, Jeroen Rovers, MD PhD, Peter Valk, PhD, Jacqueline Cloos, PhD, Tanja D. de Gruijl, PhD, Arjan A. Van de Loosdrecht, MD PhD

Blood (2019) 134 (Supplement_1): 1381.

https://doi.org/10.1182/blood-2019-127881

Published: 2019

Journal Articles

Immunophenotypically Aberrant Stem Cells in Myelodysplastic Syndromes: A Biomarker for Leukemic Progression

Margot F. Van Spronsen, MD, Theresia M. Westers, PhD, Birgit I. Witte, PhD, Gert J. Ossenkoppele, MD PhD, Arjan A. Van de Loosdrecht, MD PhD

Blood (2017) 130 (Supplement 1): 4240.

https://doi.org/10.1182/blood.V130.Suppl_1.4240.4240

Published: 2017

Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Blood (2016) 128 (22): 428.

https://doi.org/10.1182/blood.V128.22.428.428

Published: 2016

Journal Articles

Flow Cytometric Response Monitoring in MDS with Del(5q) Using a Simple 5-Parameter-Score - an Elnet Imds-Flow Experience

Uta Oelschlaegel, PhD, Theresia M. Westers, PhD, Brigitte Mohr, PhD, Ulrika Johansson, PhD, Dolores Subira, PhD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Arjan A van de Loosdrecht, MD PhD, Uwe Platzbecker, MD

Blood (2016) 128 (22): 3179.

https://doi.org/10.1182/blood.V128.22.3179.3179

Published: 2016

Journal Articles

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Shahram Kordasti, MD PhD, Tanja D. de Gruijl, PhD, Arjan A. van de Loosdrecht, MD PhD

Blood (2016) 128 (22): 4298.

https://doi.org/10.1182/blood.V128.22.4298.4298

Published: 2016

Journal Articles

Lenalidomide with or without Erythropoietin and Granulocyte-Colony Stimulating Factor Shows Efficacy in Patients with Low and Intermediate-1 Risk Myelodysplastic Syndrome with or without Del 5q, Refractory or Unlikely to Respond to Erythropoietin. Results of a HOVON89 Phase II Randomized Multicenter Study. (EudraCT 2008-002195-10)

Blood (2016) 128 (22): 224.

https://doi.org/10.1182/blood.V128.22.224.224

Published: 2016

Journal Articles

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Hetty J Bontkes, PhD, Shahram Kordasti, MD PhD, Ghulam J. Mufti, MD PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD PhD

Blood (2015) 126 (23): 4109.

https://doi.org/10.1182/blood.V126.23.4109.4109

Published: 2015

Journal Articles

Erythroid Lineage Analysis By Flow Cytometry Is of Highly Additive Value for MDS Diagnosis: A Study on Behalf of the HOVON89 Study Group

Eline MP Cremers, MD, Theresia M Westers, PhD, Canan Alhan, MD, Claudia Cali, Heleen A Visser-Wisselaar, PhD, Dana A Chitu, PhD, Marian JPL Stevens-Kroef, PhD, Pedro Silva Coelho, MD, Edo Vellenga, MDPhD, Saskia K. Klein, MDPhD, Pierre W. Wijermans, MDPhD, Georgine E De Greef, Marie-Cecile Legdeur, MD PhD, Petra Muus, MD PhD, Gert J Ossenkoppele, MD PhD, Joop H Jansen, PhD, Arjan A Van de Loosdrecht, MD PhD

Blood (2014) 124 (21): 4667.

https://doi.org/10.1182/blood.V124.21.4667.4667

Published: 2014

Journal Articles

Flow Cytometric Immunophenotyping in Myelodysplasia: Discovery and Diagnosis

Arjan A Van de Loosdrecht, MD PhD, Theresia M. Westers, PhD

Blood (2014) 124 (21): SCI-24.

https://doi.org/10.1182/blood.V124.21.SCI-24.SCI-24

Published: 2014

Journal Articles

Immunologic Recovery Following Consolidation with 90Yttrium Ibritumomab Tiuxetan (Zevalin®)-BEAM and Autologous Stem Cell Transplantation for Transformed B Cell Non-Hodkgin’s Lymphoma

Marielle J Wondergem, MD, Theresia M Westers, PhD, Otto Visser, MDhD, Josee M Zijlstra, Sonja Zweegman, MD PhD, Martine ED Chamuleau, MD

Blood (2014) 124 (21): 5882.

https://doi.org/10.1182/blood.V124.21.5882.5882

Published: 2014

Journal Articles

Diagnostic Application of Immunophenotypic Analysis of Erythroid Dysplasia in Myelodysplastic Syndromes. a Report on Behalf of the European Leukemianet-IMDS-Flow Cytometry Working Group

Theresia M Westers, PhD, Eline MP Cremers, MD, Uta Oelschlaegel, PhD, Ulrika Johansson, PhD, Peter Bettelheim, MD, Birgit Witte, PhD, Matteo G Della Porta, MD, Wolfgang Kern, MD, Arjan van de Loosdrecht, MDPhD

Blood (2014) 124 (21): 1914.

https://doi.org/10.1182/blood.V124.21.1914.1914

Published: 2014

Journal Articles

Validation Of a Multi-Diagnostic Approach Including Flow Cytometry To Identify Specific Risk Categories Within Low and Intermediate-1 Risk Myelodysplastic Syndromes Within a Prospective Clinical Trial: A Study On Behalf Of The HOVON89 Study Group

Eline M.P. Cremers, MD, Theresia M. Westers, PhD, Canan Alhan, MD, Claudia Cali, Heleen A. Visser-Wisselaar, PhD, Dana A Chitu, PhD, Marian J.P.L. Stevens-Kroef, PhD, Pedro Silva Coelho, MD, Edo Vellenga, MD, PhD, Saskia K. Klein, MD PhD, Pierre W. Wijermans, MD, PhD, Georgine E. de Greef, MD, PhD, Martijn R. Schaafsma, MD, PhD, M Marwijk Kooy, MD, PhD, Petra Muus, MD, PhD, Gert J. Ossenkoppele, MD PhD, Joop H. Jansen, PhD, Arjan A. van de Loosdrecht, MD, PhD

Blood (2013) 122 (21): 1521.

https://doi.org/10.1182/blood.V122.21.1521.1521

Published: 2013

Journal Articles

Flow Cytometry Is Highly Predictive In Excluding Myelodysplastic Syndromes In Patients With Indeterminable Cytopenia: A Prospective Analysis Of 316 Patients

Eline M.P. Cremers, MD, Theresia M Westers, PhD, Canan Alhan, MD, Marielle J. Wondergem, MD, Pino J. Poddighe, PhD, Claudia Cali, C.W.M. Schouten, Gert J. Ossenkoppele, MD PhD, Arjan A. Van de Loosdrecht, MD, PhD

Blood (2013) 122 (21): 1522.

https://doi.org/10.1182/blood.V122.21.1522.1522

Published: 2013

Journal Articles

Microrna Profiling Classifies Acute Leukemias of Ambiguous Lineage As Either Acute Myeloid Leukemia or Acute Lymphoid Leukemia

David C. de Leeuw, MD, Willemijn de van den Ancker, Fedor Denkers, Renee X. de Menezes, PhD, Theresia M. Westers, PhD, Gert J. Ossenkoppele, MD, PhD, Arjan A. Van de Loosdrecht, MD, PhD, Linda Smit, PhD

Blood (2012) 120 (21): 1443.

https://doi.org/10.1182/blood.V120.21.1443.1443

Published: 2012

Journal Articles

A Five Parameter Based Flow Cytometric Scoring System Refines the Revised International Prognostic Scoring System for Myelodysplastic Syndromes

Canan Alhan, MD, Theresia M. Westers, PhD, Eline M.P. Cremers, Claudia Cali, Gert J Ossenkoppele, MD, PhD, Arjan A. van de Loosdrecht, MD, PhD

Blood (2012) 120 (21): 3849.

https://doi.org/10.1182/blood.V120.21.3849.3849

Published: 2012

Journal Articles

Treatment with Lenalidomide in Myelodysplastic Syndromes with 5q Deletion; Results From the Patient Named Program (PNP) in the Netherlands

Imane Abouyahya, Canan Alhan, MD, Theresia M Westers, PhD, Jan Koedam, Gert Ossenkoppele, MD, PhD, Arjan A. Van de Loosdrecht, MD, PhD

Blood (2011) 118 (21): 5032.

https://doi.org/10.1182/blood.V118.21.5032.5032

Published: 2011

Journal Articles

Decreased Expression of CD62L and CD54 Correlates with Poor Cytogenetic Risk Group In Myelodysplastic Syndromes

Canan Alhan, MD, Theresia M. Westers, PhD, Claudia Cali, Floortje L. Kessler, Monique Terwijn, Gert J. Ossenkoppele, MD, PhD, Sonja Zweegman, Arjan A. Van de Loosdrecht, MD, PhD

Blood (2010) 116 (21): 2915.

https://doi.org/10.1182/blood.V116.21.2915.2915

Published: 2010

Journal Articles

Immunomodulatory Effects of Azacitidine Treatment In High Risk Myelodysplastic Syndrome

Hetty J Bontkes, Canan Alhan, Corien Eeltink, Theresia M. Westers, PhD, Gert J. Ossenkoppele, MD, PhD, Arjan A. Van de Loosdrecht, MD, PhD

Blood (2010) 116 (21): 1860.

https://doi.org/10.1182/blood.V116.21.1860.1860

Published: 2010

Journal Articles

Expansion of AML Blasts Induces CD14 Expression and Facilitates Leukemic DC Development for Therapeutic Application In AML

Willemijn van den Ancker, Pepijn G.J.T.B. Wijnands, Theresia M. Westers, PhD, Hetty J. Bontkes, PhD, Sandra van Wetering, PhD, Ada M. Kruisbeek, PhD, Gert J. Ossenkoppele, MD, PhD, Tanja D. de Gruijl, PhD., Arjan A. Van de Loosdrecht, MD, PhD

Blood (2010) 116 (21): 2193.

https://doi.org/10.1182/blood.V116.21.2193.2193

Published: 2010

NARROW

Machine Learning-Based Flow Cytometry Diagnostics in Myelodysplastic Syndromes: Validation in the HOVON89 Clinical Trial (EudraCT 2008-002195-10)

Durable Responses and Survival in High Risk AML and MDS Patients Treated with an Allogeneic Leukemia-Derived Dendritic Cell Vaccine

Immunophenotypically Aberrant Stem Cells in Myelodysplastic Syndromes: A Biomarker for Leukemic Progression

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Flow Cytometric Response Monitoring in MDS with Del(5q) Using a Simple 5-Parameter-Score - an Elnet Imds-Flow Experience

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Erythroid Lineage Analysis By Flow Cytometry Is of Highly Additive Value for MDS Diagnosis: A Study on Behalf of the HOVON89 Study Group

Flow Cytometric Immunophenotyping in Myelodysplasia: Discovery and Diagnosis

Immunologic Recovery Following Consolidation with 90Yttrium Ibritumomab Tiuxetan (Zevalin®)-BEAM and Autologous Stem Cell Transplantation for Transformed B Cell Non-Hodkgin’s Lymphoma

Diagnostic Application of Immunophenotypic Analysis of Erythroid Dysplasia in Myelodysplastic Syndromes. a Report on Behalf of the European Leukemianet-IMDS-Flow Cytometry Working Group

Validation Of a Multi-Diagnostic Approach Including Flow Cytometry To Identify Specific Risk Categories Within Low and Intermediate-1 Risk Myelodysplastic Syndromes Within a Prospective Clinical Trial: A Study On Behalf Of The HOVON89 Study Group

Flow Cytometry Is Highly Predictive In Excluding Myelodysplastic Syndromes In Patients With Indeterminable Cytopenia: A Prospective Analysis Of 316 Patients

Microrna Profiling Classifies Acute Leukemias of Ambiguous Lineage As Either Acute Myeloid Leukemia or Acute Lymphoid Leukemia

A Five Parameter Based Flow Cytometric Scoring System Refines the Revised International Prognostic Scoring System for Myelodysplastic Syndromes

Treatment with Lenalidomide in Myelodysplastic Syndromes with 5q Deletion; Results From the Patient Named Program (PNP) in the Netherlands

Decreased Expression of CD62L and CD54 Correlates with Poor Cytogenetic Risk Group In Myelodysplastic Syndromes

Immunomodulatory Effects of Azacitidine Treatment In High Risk Myelodysplastic Syndrome

Expansion of AML Blasts Induces CD14 Expression and Facilitates Leukemic DC Development for Therapeutic Application In AML

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American Society of Hematology

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American Society of Hematology

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