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Tatiana Kouznetsova
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Journal Articles

RN-1, a Potent and Selective LSD1 Inhibitor, Induces High Levels of Fetal Hemoglobin (HbF) in Anemic Baboons ( P. anubis )

Angela Rivers, MD PhD, Kestis Vaitkus, Maria Armila Ruiz, B.S., Vinzon Ibanez, Tatiana Kouznetsova, M.S., Joseph DeSimone, PhD, Donald Lavelle, PhD
Journal: Blood
Blood (2014) 124 (21): 336.
https://doi.org/10.1182/blood.V124.21.336.336
Published: 2014
Journal Articles

Elevated Levels Of γ-Globin Gene Promoter 5-Hydroxymethylcytosine are Associated With Increased DNA Hypomethylation and HbF Expression

Maria Armila Ruiz, BS, Angela Rivers, MD, PhD, Kestis Vaitkus, Tatiana Kouznetsova, M.S., Nadim Mahmud, MD, PhD, Joseph DeSimone, PhD, Donald Lavelle, PH.D.
Journal: Blood
Blood (2013) 122 (21): 438.
https://doi.org/10.1182/blood.V122.21.438.438
Published: 2013
Journal Articles

RN-1, a New and Potent Lsd-1 Inhibitor, Increases γ-Globin Expression In a Humanized Sickle Cell Mouse Model

Angela Rivers, MD, PhD, Maria Armila Ruiz, BS, Kestis Vaitkus, Tatiana Kouznetsova, M.S., Joseph DeSimone, PhD, Donald Lavelle, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 561.
https://doi.org/10.1182/blood.V122.21.561.561
Published: 2013
Journal Articles

Dynamic Regulation of 5-Hydroxymethylcytosine At the γ-Globin Promoter During Erythroid Differentiation

Maria Armila Ruiz, B.S., Kestis Vaitkus, Aparna Vasanthakumar, PhD, Angela Rivers, MD, PhD, Tatiana Kouznetsova, M.S., Joseph DeSimone, PhD, Lucy A. Godley, MD, PhD, Donald Lavelle, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 824.
https://doi.org/10.1182/blood.V120.21.824.824
Published: 2012
Journal Articles

Quantitative Analysis of Tissue and Developmental Stage-Specific Differences in DNA Methylation throughout the β-Globin Gene Locus by DNA MassARRAY,

Maria Armila Ruiz, B.S., Kestutis Vaitkus, B.S., Tatiana Kouznetsova, B.S., Joseph DeSimone, PhD, Yogen Saunthararajah, MD, Donald Lavelle, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3196.
https://doi.org/10.1182/blood.V118.21.3196.3196
Published: 2011
Journal Articles

Oral Administration of Low-Dose Decitabine and Tetrahydrouridine In Combination Increases Fetal Hemoglobin to Therapeutic Levels In the Absence of Cytotoxicity and Reduces Inter-Individual Drug Bioavailability In Baboons

Donald Lavelle, Ph.D., Kestutis Vaitkus, B.S., Maria Armila Ruiz, B.S., Cassandra List, B.S., Tatiana Kouznetsova, B.S., Joseph DeSimone, PhD, Yogen Saunthararajah, MD
Journal: Blood
Blood (2011) 118 (21): 2147.
https://doi.org/10.1182/blood.V118.21.2147.2147
Published: 2011
Journal Articles

γ-Globin Gene (HBG) Promoter Methylation and Gene Expression Is Affected by the Micro-Environment In Adult but Not Fetal Erythroid Cells

Donald Lavelle, Ph.D., Yogenthiran Saunthararajah, MD, Nadim Mahmud, MBBS, PhD, Vinzon Ibanez, PhD, Maria Armila Ruiz, PhD, Kestis Vaitkus, PhD, Tatiana Kouznetsova, Joseph DeSimone, PhD
Journal: Blood
Blood (2010) 116 (21): 4271.
https://doi.org/10.1182/blood.V116.21.4271.4271
Published: 2010
Journal Articles

Differences in BCL11A SUMOylation Are Associated with Differences in γ-Globin Expression in Primary Erythroid Cells.

Tatiana Kouznetsova, Kestis Vaitkus, Vinzon Ibanez, Joseph DeSimone, Donald Lavelle
Journal: Blood
Blood (2009) 114 (22): 458.
https://doi.org/10.1182/blood.V114.22.458.458
Published: 2009
Journal Articles

Exportin 4, a Potential Amplifier of TGF-β Signaling, Is Increased in Primary Baboon Bone Marrow Erythroblasts Following Decitabine Treatment.

Donald Lavelle, PhD, Tatiana Kouznetsova, M.S., Kestis Vaitkus, Peter Larsen, M.S., Maria Hankewych, B.S., Joseph DeSimone, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 1582.
https://doi.org/10.1182/blood.V108.11.1582.1582
Published: 2006