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Takashi Taga, MD
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KRAS mutations Frequently Coexist with High-Risk MLL Fusions and Are Independent Adverse Prognostic Factors in MLL -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, Kenichi Yoshida, MDPhD, Kana Nakatani, Yutarou Harata, Moe Higashitani, Yuri Ito, Yasuhiko Kamikubo, Yusuke Shiozawa, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, Hiroko Tanaka, BA, Ai Okada, Yasuhito Nannya, MD PhD, June Takeda, MD, Hiroo Ueno, MD PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Akio Tawa, MD PhD, Satoru Miyano, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-134648
Published: 2020
Journal Articles

Etoposide, Cytarabine and Mitoxantrone- or Fludarabine, Cytarabine and Granulocyte Colony-Stimulating Factor-Based Intensive Reinduction Chemotherapy Is Recommended for Children with Relapsed Acute Myeloid Leukemia: The Results from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R Study

Hiroshi Moritake, MD PhD, Shiro Tanaka, PhD, Takako Miyamura, MD PhD, Hideki Nakayama, MD, Norio Shiba, MD PhD, Akira Shimada, MDPhD, Kiminori Terui, MD PhD, Yuki Yuza, MD PhD, Katsuyoshi Koh, MD, Hiroaki Goto, MD, PhD, Harumi Kakuda, MD PhD, Akiko M Saito, MD PhD, Daisuke Hasegawa, MD PhD, Shotaro Iwamoto, MD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-133272
Published: 2020
Journal Articles

Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Toshihiko Imamura, MD PhD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Yukie Tanaka, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD PhD, Shuhei Karakawa, MD PhD, Shogo Kobayashi, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD PhD, Takashi Koike, MD, Shinya Rai, MD PhD, Katsutsugu Umeda, MD PhD, Hideki Sano, MD, Yujin Sekinaka, MD PhD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Fumihiko Kimura, MD PhD, Hideki Nakayama, MD, Yozo Nakazawa, MD PhD, Takashi Taga, MD PhD, Tomohiko Taki, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Katsuyoshi Koh, MD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-139312
Published: 2020
Journal Articles

Clinical Features of Children with Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis in Japan: Retrospective Nationwide Survey

Hisashi Ishida, MD PhD, Takeo Sarashina, MD PhD, Risa Matsumura, Katsutsugu Umeda, MD, PhD, Tetsuo Mitsui, MD PhD, Naoto Fujita, MD PhD, Daisuke Tomizawa, MD PhD, Kevin Y Urayama, PhD MPH, Yasushi Ishida, MD PhD, Takashi Taga, MD PhD, Masatoshi Takagi, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Toshihiko Imamura, MD PhD, Katsuyoshi Koh, MD, Akira Shimada, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2958.
https://doi.org/10.1182/blood-2019-123429
Published: 2019
Journal Articles

Predictive Factors of the Development of Leukemia in Patients with Transient Abnormal Myelopoiesis and Down Syndrome: The Jccg Study JPLSG TAM-10

Genki Yamato, MD PhD, Hideki Muramatsu, MD PhD, Tomoyuki Watanabe, PhD, Takao Deguchi, MD PhD, Shotaro Iwamoto, MD, Daisuke Hasegawa, MD PhD, Kiminori Terui, MD PhD, Takahiro Ueda, MD PhD, Tomoko Yokosuka, Tsutomu Toki, PhD, Shiro Tanaka, PhD, Ryu Yanagisawa, Katsuyoshi Koh, MD, Akiko M Saito, MD PhD, Keizo Horibe, MD PhD, Yasuhide Hayashi, MD PhD, Souichi Adachi, MD PhD, Shuki Mizutani, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Kenichiro Watanabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3833.
https://doi.org/10.1182/blood-2019-125465
Published: 2019
Journal Articles

Post-Induction Minimal Residual Disease Measured By Flow Cytometry and Deep Sequencing of Mutant GATA1 Are Both Significant Prognostic Factors for Children with Myeloid Leukemia and Down Syndrome: A Nationwide Prospective Study of the Japanese Pediatric Leukemia/Lymphoma Study Group

Takashi Taga, MD PhD, Shiro Tanaka, PhD, Kiminori Terui, MD PhD, Shotaro Iwamoto, MD, Hidefumi Hiramatsu, MD PhD, Takako Miyamura, MD PhD, Yoshiko Hashii, MD PhD, Daisuke Hasegawa, MD PhD, Hiroshi Moritake, MD PhD, Hideki Nakayama, MD, Hiroyuki Takahashi, MD PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Tsutomu Toki, PhD, Etsuro Ito, MD PhD, Katsuyoshi Koh, MD, Daiichiro Hasegawa, MD PhD, Asahito Hama, MD PhD, Akiko M Saito, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3848.
https://doi.org/10.1182/blood-2019-123302
Published: 2019
Journal Articles

Recurrent Gene Mutations in Pediatric Patients with AML By Targeted Sequencing ―the Jccg Study, JPLSG AML-05―

Taeko Kaburagi, MD, Genki Yamato, MD PhD, Norio Shiba, Kenichi Yoshida, MD PhD, Yusuke Hara, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Seishi Ogawa, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2697.
https://doi.org/10.1182/blood-2019-126545
Published: 2019
Journal Articles

Clinical Features of Pediatric Acute Myeloid Leukemia with TP53 and CDKN2A / 2B copy Number Alterations

Yusuke Hara, Tomohiko Taki, MD PhD, Genki Yamato, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD PhD, Norio Shiba, MD PhD, Taeko Kaburagi, MD, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Machiko Kawamura, MD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MD PhD, Tsutomu Toki, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2727.
https://doi.org/10.1182/blood-2019-126263
Published: 2019
Journal Articles

Significant Features of DNA Methylation at Bivalent Promotor and Repressed Polycomb Regions in Pediatric AML-the Jccg Study, JPLSG AML-05-

Genki Yamato, Tomoko Kawai, PhD, Norio Shiba, Yusuke Hara, Kentaro Ohki, MD PhD, Taeko Kaburagi, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Akira Shimada, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Souichi Adachi, MD PhD, Takashi Taga, MD PhD, Keizo Horibe, MD PhD, Seishi Ogawa, MD PhD, Kenichiro Hata, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2739.
https://doi.org/10.1182/blood-2019-125025
Published: 2019
Journal Articles

The Detection of Minor Clones with Somatic KIT D816V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/Lymphoma Study Group

Koji Sasaki, MD, Yuri Uchiyama, MD PhD, Junji Ikeda, Masahiro Yoshitomi, Yuko Shimosato-Wada, Mayu Tokumasu, Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kentaro Oki, MD PhD, Genki Yamato, MD PhD, Yusuke Hara, Akitoshi Kinoshita, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, MD PhD, Naomichi Matsumoto, MD PhD, Shuichi Ito, MD PhD, Yasuhide Hayashi, MD PhD, Norio Shiba
Journal: Blood
Blood (2019) 134 (Supplement_1): 1419.
https://doi.org/10.1182/blood-2019-127656
Published: 2019
Journal Articles

Coexistence and Prognostic Significance of EVI1 Expression and Driver Mutations in KMT2A -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kana Nakatani, Yasuhiko Kamikubo, MD, PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Nobutaka Kiyokawa, MD PhD, Seishi Ogawa, MD PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1409.
https://doi.org/10.1182/blood-2019-124652
Published: 2019
Journal Articles

Effect of Age on the Prognosis of Molecular Abnormalities in Pediatric Acute Myeloid Leukemia

Yusuke Hara, MD PhD, Norio Shiba, MD PhD, Genki Yamato, MD PhD, Kentaro Ohki, MD PhD, Manabu Sotomatsu, MD PhD, Ken Tabuchi, MD, Daisuke Tomizawa, MD PhD, Tomohiko Taki, MD PhD, Akitoshi Kinoshita, MD PhD, Nobutaka Kiyokawa, MD PhD, Hirokazu Arakawa, MD PhD, Masabumi Shibuya, MD PhD, Takashi Taga, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, MD PhD, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1506.
https://doi.org/10.1182/blood-2018-99-118097
Published: 2018
Journal Articles

Comprehensive Analysis of 343 Genes Using Targeted Sequencing Panel By Next-Generation Sequencer in 77 Pediatric AML Patients with Normal and Complex Karyotypes: Jccg Study, JPLSG AML-05

Taeko Kaburagi, Genki Yamato, MD PhD, Norio Shiba, MD, Kenichi Yoshida, MD PhD, Yusuke Hara, MD PhD, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MDPhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1530.
https://doi.org/10.1182/blood-2018-99-114632
Published: 2018
Journal Articles

Recurrent Genomic Aberrations of D-Type Cyclins Are Therapeutic Targets of CDK4/6 Inhibitors in t(8;21) and MLL -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kazutaka Fukumura, PhD, Kana Nakatani, Yuki Noguchi, Saho Takasaki, Mina Noura, Yusuke Shiozawa, MD, PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Ai Okada, Yasuhito Nannya, MD PhD, June Takeda, MD, Hiroo Ueno, MD, Norio Shiba, MD PhD, Genki Yamato, MD PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Akio Tawa, MD PhD, Yasuhide Hayashi, MD PhD, Hiroyuki Mano, MD, PhD, Satoru Miyano, PhD, Yasuhiko Kamikubo, MD, PhD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2018-99-111073
Published: 2018
Journal Articles

Negative CD19 Expression Is Associated with Inferior Relapse-Free Survival in RUNX1-RUNX1T1 -Positive Acute Myeloid Leukemia; The Japanese Pediatric Leukemia/Lymphoma Study Group Experience from the AML-05 Study

Toshihiko Imamura, MD PhD, Kenichi Sakamoto, MD PhD, Norio Shiba, MD PhD, Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MD PhD, Yoshiko Hashii, MD, PhD, Akiko Saito, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2810.
https://doi.org/10.1182/blood-2018-99-115553
Published: 2018
Journal Articles

Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD, Shuhei Karakawa, MD, Shogo Kobayashi, MD, Hideki Sano, MD, Takashi Koike, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD, PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Hideki Nakayama, MD, Yozo Nakazawa, MD, PhD, Toshihiko Imamura, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Katsuyoshi Koh, MD, Atsushi Manabe, MD PhD, Tomohiko Taki, MD PhD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2824.
https://doi.org/10.1182/blood-2018-99-118627
Published: 2018
Journal Articles

Hematopoietic Stem-Cell Transplantation in Children with Refractory Acute Myeloid Leukemia

Yasuhiro Okamoto, MD, Kazuko Kudo, MD PhD, Ken Tabuchi, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Hiroaki Goto, MD, Hiromasa Yabe, MD, PhD, Yozo Nakazawa, MD, PhD, Katsuyoshi Koh, MD, Kazuhiro Ikegame, MD PhD, Nao Yoshida, MD PhD, Naoyuki Uchida, MD PhD, Kenichiro Watanabe, MD PhD, Yuuki Koga, MD PhD, Masami Inoue, MD, Koji Kato, MD PhD, Yoshiko Atsuta, MD PhD, Hiroyuki Ishida, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4632.
https://doi.org/10.1182/blood-2018-99-111322
Published: 2018
Journal Articles

Hematopoietic Cell Transplantation for Children with Acute Megakaryoblastic Leukemia without Down Syndrome

Asahito Hama, Takashi Taga, MD PhD, Daisuke Tomizawa, MD PhD, Hideki Muramatsu, MD PhD, Daiichiro Hasegawa, MD PhD, Souichi Adachi, MD PhD, Nao Yoshida, MD PhD, Maiko Noguchi, MD, Masami Inoue, MD, Keiko Oakada, MD, Katsuyoshi Koh, MD, Yoshiko Atsuta, MD PhD, Hiroyuki Ishida, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4671.
https://doi.org/10.1182/blood-2018-99-114062
Published: 2018
Journal Articles

Biology and Prognostic Markers in Young Children with Acute Myeloid Leukemia -the Jccg Study, JPLSG AML-05-

Yusuke Hara, Norio Shiba, MD, Genki Yamato, MD, Jun Okubo, MD PhD, Kentaro Ohki, MD PhD, Myoung-Ja Park, MD PhD, Manabu Sotomatsu, MD PhD, Daisuke Tomizawa, MD PhD, Tomohiko Taki, MD PhD, Akitoshi Kinoshita, MD PhD, Nobutaka Kiyokawa, MD PhD, Takashi Taga, MD PhD, Hirokazu Arakawa, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1392.
https://doi.org/10.1182/blood.V130.Suppl_1.1392.1392
Published: 2017
Journal Articles

RNA Sequencing Illustrates the Genetic Backgrounds of Pediatric Acute Myeloid Leukemia

Norio Shiba, MD, Kenichi Yoshida, MD PhD, Yusuke Hara, Genki Yamato, MD, Masashi Sanada, MD PhD, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Jun Okubo, MD PhD, Myoung-JA PARK, Daisuke Tomizawa, MD PhD, Tomohiko Taki, MD PhD, Manabu Sotomatsu, MD PhD, Keizo Horibe, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Akio Tawa, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1410.
https://doi.org/10.1182/blood.V130.Suppl_1.1410.1410
Published: 2017