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Journal Articles

Platelet Decrease and Efficacy of Platelet-Rich Plasma Return for Peripheral Blood Stem Cell Apheresis

Takahiro Shima, MD PhD, Teppei Sakoda, MD, Tomoko Henzan, MD, Yuya Kunisaki, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD, Toshihiro Miyamoto, MD PhD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-142316

Published: 2020

Journal Articles

A Fast and Accurate Diagnostic Method for Ph-like ALL Using the Ncounter System

Kensuke Sasaki, MD, Kohta Miyawaki, MD PhD, Yuichiro Semba, MD PhD, Koji Kato, MD PhD, Jumpei Nogami, PhD, Takeshi Sugio, MD PhD, Toshihiro Miyamoto, MD PhD, Yoshikiyo Ito, MD PhD, Koji Nagafuji, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 375.

https://doi.org/10.1182/blood-2019-129625

Published: 2019

Journal Articles

Paics Inhibition Is a Potential Therapeutic Strategy for MYC-Positive DLBCL

Kohta Miyawaki, MD PhD, Takuji Yamauchi, MD PhD, Takeshi Sugio, MD PhD, Kensuke Sasaki, MD, Hiroaki Miyoshi, MD PhD, Simon Osborne, PhD, Deborah Taylor, PhD, Koichi Ohshima, MD PhD, Koji Kato, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 396.

https://doi.org/10.1182/blood-2019-129613

Published: 2019

Journal Articles

CRISPR-Cas9 Screen Identifies XPO7 As a Potential Therapeutic Target for TP53 -Mutated AML

Yuichiro Semba, MD PhD, Takuji Yamauchi, MD PhD, Fumihiko Nakao, MD, Jumpei Nogami, PhD, Matthew C. Canver, MD PhD, Luca Pinello, PhD, Daniel E. Bauer, MD PhD, Koichi Akashi, MD PhD, Takahiro Maeda, MD PhD

Blood (2019) 134 (Supplement_1): 3784.

https://doi.org/10.1182/blood-2019-129623

Published: 2019

Journal Articles

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 2516.

https://doi.org/10.1182/blood-2019-129372

Published: 2019

Journal Articles

Somatic Mutations Potentiating RAS-MAPK Signaling Confer Resistant Potential Against FLT3-Inhibitors to Acute Myelogenous Leukemia

Masayasu Hayashi, MD PhD, Yoshikane Kikushige, MD PhD, Takuya Harada, MD, Toshihiro Miyamoto, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 910.

https://doi.org/10.1182/blood-2019-130694

Published: 2019

Journal Articles

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Fumihiko Nakao, MD, Takuji Yamauchi, MD PhD, Yuichiro Semba, MD PhD, Jumpei Nogami, PhD, Koichi Akashi, MD PhD, Takahiro Maeda, MD PhD

Blood (2019) 134 (Supplement_1): 912.

https://doi.org/10.1182/blood-2019-129237

Published: 2019

Journal Articles

Paics, a De Novo Purine Synthetic Enzyme, Is a Novel Target for AML Therapy

Takuji Yamauchi, MD PhD, Kohta Miyawaki, MD, Yuichiro Semba, MD PhD, Fumihiko Nakao, MD, Takeshi Sugio, MD PhD, Kensuke Sasaki, MD, Jumpei Nogami, PhD, Matthew C. Canver, MD PhD, Simon Osborne, PhD, Luca Pinello, PhD, Deborah Taylor, PhD, Daniel E. Bauer, MD PhD, Koichi Akashi, MD PhD, Takahiro Maeda, MD PhD

Blood (2019) 134 (Supplement_1): 1390.

https://doi.org/10.1182/blood-2019-127047

Published: 2019

Journal Articles

Rational Targeting of a NuRD Sub-Complex for Fetal Hemoglobin Induction Following Comprehensive in Situ Mutagenesis

Mir Hossain, PhD, Falak Sher, PhD, Davide Seruggia, PhD, Vivien Schoonenberg, BS, Mitchel A. Cole, BS, Paolo Cifani, PhD, Laura Dassama, PhD, Claudio Macias-Trevino, BS, Matthew C. Canver, MD PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Luca Pinello, PhD, Takahiro Maeda, MD PhD, Alex Kentsis, MD PhD, Stuart H. Orkin, MD, Daniel E. Bauer, MD PhD

Blood (2018) 132 (Supplement 1): 2342.

https://doi.org/10.1182/blood-2018-99-117043

Published: 2018

Journal Articles

Erythropoietin Signaling Regulates Heme Biosynthesis

Jacky Chung, PhD, Johannes G. Wittig, Alireza Ghamari, Manami Maeda, MD, PhD, Harvey Lodish, PhD, Daniel E. Bauer, MD, PhD, Stuart H. Orkin, MD, Alan B. Cantor, MD, PhD, Takahiro Maeda, MD PhD, Harry A. Dailey, PhD, Barry H. Paw, MD, PhD

Blood (2016) 128 (22): 543.

https://doi.org/10.1182/blood.V128.22.543.543

Published: 2016

Journal Articles

Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing)

Blood (2015) 126 (23): 638.

https://doi.org/10.1182/blood.V126.23.638.638

Published: 2015

Journal Articles

The LRF/ZBTB7A Transcription Factor Is a BCL11A-Independent Repressor of Fetal Hemoglobin

Blood (2015) 126 (23): 2.

https://doi.org/10.1182/blood.V126.23.2.2

Published: 2015

Journal Articles

Clathrin Assembly Protein CALM Is Necessary for Leukemia Cell Proliferation and Erythroid Development Via Regulating Transferrin Receptor Endocytosis

Yuichi Ishikawa, MD, PhD, Manami Maeda, MD, PhD, Min Li, PhD, Sung-Uk Lee, PhD, Julie Teruya Feldstein, MD, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD, Mitchell J. Weiss, MD, PhD, John E Heuser, MD, Takahiro Maeda, MD, PhD

Blood (2011) 118 (21): 244.

https://doi.org/10.1182/blood.V118.21.244.244

Published: 2011

Journal Articles

LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation

Sung-Uk Lee, PhD, Manami Maeda, MD, PhD, Anne E. Wilson, Min Li, PhD, Yuichi Ishikawa, MD, PhD, Adrian M. Judd, PhD, Nagisa Sakurai, PhD, Emma Fiorini, PhD, Freddy Radtke, PhD, Minhong Yan, PhD, Hugh Robson Macdonald, PhD, Ching-Cheng Chen, Takahiro Maeda, MD, PhD

Blood (2011) 118 (21): 44.

https://doi.org/10.1182/blood.V118.21.44.44

Published: 2011

Journal Articles

Clathrin Assembly Protein CALM Plays a Key Role In Erythroid Differentiation Via Regulating Transferrin Receptor Endocytosis

Yuichi Ishikawa, MD, PhD, Manami Maeda, MD, PhD, Min Li, PhD, Sung-Uk Lee, PhD, Julie Teruya Feldstein, MD, Yumiko Mori, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD, John E Heuser, MD, Takahiro Maeda, MD, PhD

Blood (2010) 116 (21): 4256.

https://doi.org/10.1182/blood.V116.21.4256.4256

Published: 2010

Journal Articles

Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool.

Sung-UK Lee, PhD, Min Li, PhD, Manami Maeda, Nagisa Sakurai, Yuichi Ishikawa, MD, PhD, Freddy Radtke, Minhong Yan, Hugh Robson Macdonald, Takahiro Maeda, MD, PhD

Blood (2010) 116 (21): 2633.

https://doi.org/10.1182/blood.V116.21.2633.2633

Published: 2010

Journal Articles

Characterization of Leukemia-Initiating Cells in a Transgenic Model of Chronic Phase Chronic Myelogenous Leukemia (CML).

Bin Zhang, MD, PhD, Yin Wei Ho, Sung-UK Lee, PhD, Takahiro Maeda, MD, PhD, Claudia Huettner, PhD, Ravi Bhatia, MD

Blood (2009) 114 (22): 858.

https://doi.org/10.1182/blood.V114.22.858.858

Published: 2009

Journal Articles

LRF Regulates Self-Renewal of Hematopoietic Stem Cells by Blocking Notch1-Mediated T Cell Differentiation

Sung-UK Lee, PhD, Manami Maeda, MD, PhD, Nagisa Sakurai, PhD, Julie Teruya-Feldstein, MD, Freddy Radtke, PhD, Takahiro Maeda, MD, PhD

Blood (2008) 112 (11): 75.

https://doi.org/10.1182/blood.V112.11.75.75

Published: 2008

Journal Articles

The Proto-Oncogene LRF Is Essential for Normal Mature B Cell Development and Germinal Center Formation.

Nagisa Sakurai, PhD, Manami Maeda, MD, PhD, Sung-UK Lee, PhD, Julie Teruya-Feldstein, MD, Takahiro Maeda, MD, PhD

Blood (2008) 112 (11): 1788.

https://doi.org/10.1182/blood.V112.11.1788.1788

Published: 2008

Journal Articles

LRF/Pokemon Plays a Pivotal Role in B Versus T Lymphoid Lineage Fate Decision at the Early Lymphoid Progenitor Stage by Opposing Notch1 Signaling.

Takahiro Maeda, MD, PhD, Taha Merghoub, PhD, Lin Dong, MD, Manami Maeda, MD.PhD., Robin Hobbs, PhD, Johannes Zakrzewski, MD, Marcel van den Brink, MD.PhD., Hirokazu Shigematsu, MD.PhD., Koichi Akashi, MD.PhD., Arthur Zelent, PhD, Julie Teruya-Feldstein, MD, Giorgio Cattoretti, MD, Pier Paolo Pandolfi, MD.PhD.

Blood (2006) 108 (11): 778.

https://doi.org/10.1182/blood.V108.11.778.778

Published: 2006

NARROW

Platelet Decrease and Efficacy of Platelet-Rich Plasma Return for Peripheral Blood Stem Cell Apheresis

A Fast and Accurate Diagnostic Method for Ph-like ALL Using the Ncounter System

Paics Inhibition Is a Potential Therapeutic Strategy for MYC-Positive DLBCL

CRISPR-Cas9 Screen Identifies XPO7 As a Potential Therapeutic Target for TP53 -Mutated AML

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

Somatic Mutations Potentiating RAS-MAPK Signaling Confer Resistant Potential Against FLT3-Inhibitors to Acute Myelogenous Leukemia

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Paics, a De Novo Purine Synthetic Enzyme, Is a Novel Target for AML Therapy

Rational Targeting of a NuRD Sub-Complex for Fetal Hemoglobin Induction Following Comprehensive in Situ Mutagenesis

Erythropoietin Signaling Regulates Heme Biosynthesis

Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing)

The LRF/ZBTB7A Transcription Factor Is a BCL11A-Independent Repressor of Fetal Hemoglobin

Clathrin Assembly Protein CALM Is Necessary for Leukemia Cell Proliferation and Erythroid Development Via Regulating Transferrin Receptor Endocytosis

LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation

Clathrin Assembly Protein CALM Plays a Key Role In Erythroid Differentiation Via Regulating Transferrin Receptor Endocytosis

Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool.

Characterization of Leukemia-Initiating Cells in a Transgenic Model of Chronic Phase Chronic Myelogenous Leukemia (CML).

LRF Regulates Self-Renewal of Hematopoietic Stem Cells by Blocking Notch1-Mediated T Cell Differentiation

The Proto-Oncogene LRF Is Essential for Normal Mature B Cell Development and Germinal Center Formation.

LRF/Pokemon Plays a Pivotal Role in B Versus T Lymphoid Lineage Fate Decision at the Early Lymphoid Progenitor Stage by Opposing Notch1 Signaling.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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