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Sydney X. Lu, MD PhD
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Journal Articles

A Pilot Study Evaluating Lenalidomide and CC-486 in Combination with Radiotherapy for Patients with Plasmacytoma (LENAZART study)

Urvi A Shah, MD, Kelly Werner, RN, Elizabet Tavitian, BS, Sean Devlin, PhD, Sham Mailankody, MBBS, Neha Korde, MD, Malin Hultcrantz, MD PhD, Carlyn Tan, MD, Sydney X. Lu, MD PhD, Eric L Smith, MDPhD, Francesco Maura, MD, Dhwani Patel, MD, Gunjan L. Shah, MDMS, Oscar B Lahoud, MD, Michael Scordo, MD, Richard J Lin, MDPhD, Parastoo B. Dahi, MD, Heather J Landau, MD, David J. Chung, MD PhD, Hani Hassoun, MD, Jonathan Landa, MD, Bernard O'Malley, Christopher Barker, MD, Taha Merghoub, PhD, Sergio A. Giralt, MD, Ola Landgren, MD PhD, Joachim Yahalom, MD, Alexander M. Lesokhin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–10.
https://doi.org/10.1182/blood-2020-141131
Published: 2020
Journal Articles

Long-Term Sustained Minimal Residual Disease (MRD) Negativity in Patients with Multiple Myeloma Treated with Continuous Lenalidomide Maintenance Therapy: A Clinical and Correlative Phase 2 Study

Benjamin Diamond, MD, Neha Korde, MD, Alexander M. Lesokhin, MD, Eric L Smith, MDPhD, Urvi A Shah, MD, Sham Mailankody, MBBS, Malin Hultcrantz, MD PhD, Hani Hassoun, MD, Sydney X. Lu, MD PhD, Carlyn Tan, MD, Donna Massey, MSN, RN, Meghan Salcedo, BSN, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Julia Schlossman, BA, Aisara Chansakul, BS, Angela Harrison, MS, Amanda Kathryn Ciardiello, Elizabet Tavitian, BS, Tala Shekarkhand, BS, Casey Piacentini, BS, Even H Rustad, MD PhD, Venkata D Yellapantula, Francesco Maura, MD, Tim J Peterson, PharmD, Andriy Derkach, PhD, Sean Devlin, PhD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan L. Shah, MDMS, Oscar B Lahoud, MD, Katie Thoren, Kazunori Murata, Lakshmi Ramanathan, PhD, Maria E. Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio A. Giralt, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-140152
Published: 2020
Journal Articles

VRd Versus KRd Safety Profiles in Newly Diagnosed Multiple Myeloma Patients Using Real-World Evidence Data from a Single Institution: VRd Has High Rates of Chronic Neuropathy, and KRd Has Low Rates of Cardiopulmonary or Renal Toxicities When Using Optimized IV Fluid Management Coupled with Baseline Cardiac Workup

Carlyn Tan, MD, Benjamin Diamond, MD, Malin Hultcrantz, MD PhD, Neha Korde, MD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Hani Hassoun, MD, Urvi A Shah, MD, Sydney X. Lu, MD PhD, Dhwani Patel, MD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Andriy Derkach, PhD, Sergio A. Giralt, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-141988
Published: 2020
Journal Articles

Weekly Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab (wKRd-D) Combination Therapy in Newly Diagnosed Multiple Myeloma: Final Results from a Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Hani Hassoun, MD, Carlyn Tan, MD, Urvi A Shah, MD, Sydney X. Lu, MD PhD, Benjamin Diamond, MD, Meghan Salcedo, RN, Kelly Werner, RN, Jenna Rispoli, RN, Julia Caple, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Isabel Concepcion, NP, Ciardello Amanda, MS, Aisara Chansakul, BS, Julia Schlossman, BA, Elizabet Tavitian, BS, Tala Shekarkhand, BS, Angela Harrison, MS, Casey Piacentini, BS, Even H Rustad, MD PhD, Venkata Yellapantula, PhD, Francesco Maura, MD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E. Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Andriy Derkach, PhD, Sergio A. Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-142466
Published: 2020
Journal Articles

ZRSR2 Mutation Induced Minor Intron Retention Drives MDS and Diverse Cancer Predisposition Via Aberrant Splicing of LZTR1

Daichi Inoue, MDPhD, Jacob T. Polaski, Justin Taylor, MD, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J. Hogg, PhD BSc, Yasutaka Hayashi, MDPhD, Jose Mario Bello Pineda, Alexander V Penson, PhD, Ettaib El Marabti, Caroline Erickson, Miki Fukumoto, Hiromi Yamazaki, PhD, Chie Fukui, Sydney X. Lu, MD PhD, Benjamin H. Durham, Bo Liu, PhD, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, PhD, Guo-Liang Chew, Frank McCormick, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-136445
Published: 2020
Journal Articles

Association of Patient Activity Bioprofiles with Hrqol and Clinical Responses: A Prospective Novel Trial Using Mobile Wearables in Newly Diagnosed Multiple Myeloma Patients

Neha Korde, MD, Elizabet Tavitian, BS, Andriy Derkach, PhD, Andrew Zarski, Meghan Salcedo, BSN, RN, Sham Mailankody, MBBS, Hani Hassoun, MD, Alexander M. Lesokhin, MD, Nikoletta Lendvai, MDPhD, Eric L Smith, MDPhD, Malin Hultcrantz, MD PhD, Sydney X. Lu, MD PhD, Carlyn Tan, MD, Urvi A Shah, MD, Benjamin Diamond, MD, Dhwani Patel, MD, Gunjan L. Shah, MDMS, Sergio A. Giralt, MD, Sean Devlin, PhD, Thomas Atkinson, Joseph Lengfellner, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–28.
https://doi.org/10.1182/blood-2020-142082
Published: 2020
Journal Articles

VTE Rates and Safety Analysis of Newly Diagnosed Multiple Myeloma Patients Receiving Carfilzomib-Lenalidomide-Dexamethasone (KRD) with or without Rivaroxaban Prophylaxis

Katrina M Piedra, PharmD, Hani Hassoun, MD, Larry W. Buie, PharmD, BCOP, FASHP, Sean M. Devlin, PhD, Jessica Flynn, BS, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sydney X Lu, MD PhD, Sham Mailankody, MBBS, Urvi A Shah, MD, Eric L Smith, MD PhD, Ola Landgren, MD PhD, Neha Korde, MD, Tim J Peterson, PharmD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1835.
https://doi.org/10.1182/blood-2019-124403
Published: 2019
Journal Articles

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Daichi Inoue, MD PhD, Chew Guo-Liang, Bo Liu, PhD, Stanley C Lee, PhD, Brittany C Michel, Joey Pangallo, B.S., Andrew R D'Avino, Khrystyna North, Lillian E Bitner, BSc, Muran Xiao, Susumu Kobayashi, Akihide Yoshimi, MD PhD, Hana Cho, MSc, Sydney X Lu, MD PhD, Justin Taylor, MD, Cigall Kadoch, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 637.
https://doi.org/10.1182/blood-2019-124616
Published: 2019
Journal Articles

MALDI-TOF Mass Spectrometry in Serum for the Follow-up of Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab-Based Combination Therapy

Marion Eveillard, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Eric L Smith, MD PhD, Hani Hassoun, MD, Urvi A Shah, MD, Sydney X Lu, MD PhD, Neha Korde, MD, Ola Landgren, MD PhD, Katie Thoren, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4377.
https://doi.org/10.1182/blood-2019-128938
Published: 2019
Journal Articles

Long-Term Sustained Minimal Residual Disease (MRD) Negativity in Multiple Myeloma Patients Treated with Lenalidomide Maintenance Therapy: A Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Donna Mastey, RN, Alexander M. Lesokhin, MD, Eric L Smith, MD PhD, Urvi A Shah, MD, Sham Mailankody, MBBS, Malin Hultcrantz, MD PhD, Hani Hassoun, MD, Sydney X Lu, MD PhD, Meghan Salcedo, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Julia Schlossman, BA, Aisara Chansakul, BS, Angela Harrison, MS, Amanda Ciardiello, BS, Elizabeth Tavitian, BS, Tala Shekarkhand, BS, Even Rustad, MD, Venkata Yellapantula, PhD, Francesco Maura, MD, Tim J Peterson, PharmD, Sean M. Devlin, PhD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, PhD, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3127.
https://doi.org/10.1182/blood-2019-125842
Published: 2019
Journal Articles

An Observational, Retrospective Analysis of Retreatment with Carfilzomib in the Management of Patients with Multiple Myeloma

Tim J Peterson, PharmD, Neha Korde, MD, Hani Hassoun, MD, Sham Mailankody, MBBS, Alexander M. Lesokhin, MD, Malin Hultcrantz, MD PhD, Urvi A Shah, MD, Eric L Smith, MD PhD, Sydney X Lu, MD PhD, Heather J Landau, MD, Gunjan L. Shah, MD, Michael Scordo, MD, Oscar B Lahoud, MD, Sergio A Giralt, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5554.
https://doi.org/10.1182/blood-2019-124376
Published: 2019
Journal Articles

Weekly Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab (wKRd-D) Combination Therapy Provides Unprecedented MRD Negativity Rates in Newly Diagnosed Multiple Myeloma: A Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Hani Hassoun, MD, Eric L Smith, MD PhD, Urvi A Shah, MD, Sydney X Lu, MD PhD, Donna Mastey, RN, Meghan Salcedo, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Angela Harrison, MS, Aisara Chansakul, BS, Even H Rustad, MD, Venkata Yellapantula, PhD, Francesco Maura, MD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, PhD, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sean M. Devlin, PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 862.
https://doi.org/10.1182/blood-2019-126378
Published: 2019
Journal Articles

Therapeutic Targeting of an RNA Splicing Factor Network for the Treatment of Myeloid Neoplasms

Sydney X. Lu, MD PhD, Eric Wang, Alessandro Pastore, Chen Xufeng, PhD, Jochen Imig, PhD, Stanley C Lee, PhD, Yohana Ghebrechristos, Akihide Yoshimi, MD, Lillian E Bitner, BSc, Michelle Ki, BSc, Andreas Kloetgen, Kuan-Ting Lin, PhD, Raoul Tibes, MD PhD, Adrian R. Krainer, PhD, Taisuke Uehara, Takashi Owa, PhD, Iannis Aifantis, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 427.
https://doi.org/10.1182/blood-2018-99-111430
Published: 2018
Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 937.
https://doi.org/10.1182/blood-2018-99-111552
Published: 2018
Journal Articles

Bone Marrow-Based and Longitudinal Blood-Based MRD Tracking in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone (DKRd): A Correlative and Clinical Phase II Study

Ola Landgren, MD PhD, Katie Thoren, PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Nikoletta Lendvai, MD PhD, Sham Mailankody, MBBS, Eric L. Smith, MD PhD, Hani Hassoun, MD, Sydney X. Lu, MD PhD, Donna Mastey, RN, Meghan Salcedo, RN, Victoria Diab, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, Angela Harrison, MS, Even H Rustad, MD, Venkata Yellapantula, PhD, Theresia Akhlaghi, BS, Heather J. Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan L. Shah, MD MS, Oscar B Lahoud, MD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3281.
https://doi.org/10.1182/blood-2018-99-114311
Published: 2018