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Journal Articles

Venetoclax Combined with Daunorubicin and Cytarabine (2 + 6) in Acute Myeloid Leukemia: Updated Results of a Phase II Trial

Xiaohui Suo, Dongmei Wang, Fang Zheng, Suping Zhang, Congcong Zhang, Yinling Li, Rui Shi, Yan Wu, Sisi Yang, Liyun Zhao, Zongjiu Jiao, Jie Liu, Ling Zhang, Ling Li, Zhihua Zhang, Xinxiao Lu, Linyu Yuan, Sifeng Gao, Jilei Zhang, Xingli Zhao, Guanchen Bai, Yingchang Mi, Kaiqi Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 969.
https://doi.org/10.1182/blood-2023-179205
Published: 2023
Journal Articles

Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia

Yun Chen, Liguang Chen, Jian Yu, Emanuela M. Ghia, Michael Y. Choi, Ling Zhang, Suping Zhang, Elsa Sanchez-Lopez, George F. Widhopf, II, Karen Messer, Laura Z. Rassenti, Catriona Jamieson, Thomas J. Kipps
Journal: Blood
Blood (2019) 134 (13): 1084–1094.
https://doi.org/10.1182/blood.2019001366
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Cirmtuzumab Inhibits Non-Canonical Wnt Signaling without Enhancing Canonical Wnt/β-Catenin Signaling in Chronic Lymphocytic Leukemia

Han Zhang, PhD, Suping Zhang, PhD, Emanuela M. Ghia, PhD, Michael Y. Choi, MD, Jieyu Zhang, MS, Liguang Chen, PhD, George F. Widhopf II, PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2652.
https://doi.org/10.1182/blood-2018-99-119606
Published: 2018
Journal Articles

Treatment for X-Linked Agammaglobulinemia with Allogeneic Umbilical Cord Blood Stem Cell Transplantation from HLA-Matched Sibling Confirmed Healthy through Prenatal Diagnosis

Dingming Wan, Ran Zhang, Meng Wang, Li Li, Weijie Cao, Suping Zhang, Kai Sun, MD, Xiaona Chen, Na Zhang
Journal: Blood
Blood (2018) 132 (Supplement 1): 5771.
https://doi.org/10.1182/blood-2018-99-116135
Published: 2018
Journal Articles

Structural Features of ROR1 Required for Complexing with ROR2 and Enhancing Chemokine-Induced Migration and Leukemia-Cell Proliferation, Which Can be Blocked By the Anti-ROR1 Mab Cirmtuzumab (UC-961)

Jian Yu, PhD, Liguang Chen, MD PhD, George F. Widhopf, II, PhD, Suping Zhang, PhD, Bing Cui, PhD, Rongrong Wu, PhD, Ling Zhang, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1741.
https://doi.org/10.1182/blood.V126.23.1741.1741
Published: 2015
Journal Articles

Loss of Autophagy Leads to Megakaryocytes Differentiation Failure and Defective Platelets Function

Yan Cao, BS, Jinyang Cai, MS, Xin Li, BS, Yixuan Fang, BS, Suping Zhang, MD PhD, Na Yuan, BS, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 4148.
https://doi.org/10.1182/blood.V124.21.4148.4148
Published: 2014
Journal Articles

Autophagy Collaborates with Ubiquitination to Down-Regulate Oncoprotein E2A/Pbx1 in B Cell Acute Lymphoblastic Leukemia

Suping Zhang, MD PhD, Lin Song, BS, Na Yuan, BS, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Xin Li, BS, Zhijian Wang, MS, Jinyang Cai, MS, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 5276.
https://doi.org/10.1182/blood.V124.21.5276.5276
Published: 2014
Journal Articles

Bafilomycin A1 Targets Both Autophagy and Apoptosis Pathways in Pediatric t(1;19) Pre-B Acute Lymphoblastic Leukemia Cells

Na Yuan, BS, Lin Song, BS, Suping Zhang, MD PhD, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Zhijian Wang, MS, Xin Li, BS, Jinyang Cai, MS, Yi Zhang, PhD, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 3699.
https://doi.org/10.1182/blood.V124.21.3699.3699
Published: 2014
Journal Articles

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Bing Cui, Liguang Chen, Suping Zhang, Marek Mraz, Jessie-F. Fecteau, Jian Yu, Emanuela M. Ghia, Ling Zhang, Lei Bao, Laura Z. Rassenti, Karen Messer, George A. Calin, Carlo M. Croce, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (4): 546–554.
https://doi.org/10.1182/blood-2014-03-559690
Published: 2014
Includes: Supplemental data
Journal Articles

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Bing Cui, Ph.D, George F. Widhopf, II, PhD, Charles E. Prussak, Ph.D., Christina C.N. Wu, PhD, Anil Sadarangani, PhD, Suping Zhang, PhD, Fitzgerald Lao, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1637.
https://doi.org/10.1182/blood.V122.21.1637.1637
Published: 2013
Journal Articles

A6 Peptide Is Selectively Cytotoxic For Chronic Lymphocytic Leukemia Cells

Suping Zhang, PhD, Hsien Lai, BS, Grace Liu, Laura Rassenti, PhD, Michael Y. Choi, MD, Stephen B Howell, MD, Malcolm Finlayson, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5303.
https://doi.org/10.1182/blood.V122.21.5303.5303
Published: 2013
Journal Articles

Impact of oxygen concentration on growth of mesenchymal stromal cells from the marrow of patients with chronic lymphocytic leukemia

Brief Report
Jessie-F. Fecteau, Davorka Messmer, Suping Zhang, Bing Cui, Liguang Chen, Thomas J. Kipps
Journal: Blood
Blood (2013) 121 (6): 971–974.
https://doi.org/10.1182/blood-2012-08-447813
Published: 2013
Includes: Supplemental data
Journal Articles

Human ROR1 Activates AKT and Accelerates Leukemia Cell Proliferation

Suping Zhang, PhD, Liguang Chen, MD, PhD, Ling Zhang, Jian Yu, PhD, Laura Z. Rassenti, Ph.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3872.
https://doi.org/10.1182/blood.V120.21.3872.3872
Published: 2012
Journal Articles

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Suping Zhang, PhD, Christina C.N. Wu, Ph.D., Jessie-Farah Fecteau, Ph.D., Bing Cui, PhD, Rongrong Wu, Laura Z. Rassenti, Ph.D., Fitzgerald S. Lao, B.S., Rommel Tawatao, B.S., Stefan Weigland, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 927.
https://doi.org/10.1182/blood.V118.21.927.927
Published: 2011
Journal Articles

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

Bing CUi, PhD, George F. Widhopf, II, PhD, Jian Yu, PhD, Daniel Martinez, BS, Esther Avery, B.S., Suping Zhang, PhD, Liguang Chen, MD, PhD, Rongrong Wu, Christina C.N. Wu, Ph.D., Charles Prussak, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 984.
https://doi.org/10.1182/blood.V118.21.984.984
Published: 2011
Journal Articles

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Jessie-Farah Fecteau, Ph.D., Davorka Messmer, PhD, Suping Zhang, PhD, Bing Cui, PhD, Liguang Chen, MD, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 2839.
https://doi.org/10.1182/blood.V118.21.2839.2839
Published: 2011
Journal Articles

Efficient Gene Delivery to Chronic Lymphocytic Leukemia (CLL) Cells with Microbubbles Bearing ROR1 Antibody

Suping Zhang, PhD, Wenjin Cui, PhD, Robert Mattrey, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 2857.
https://doi.org/10.1182/blood.V118.21.2857.2857
Published: 2011
Journal Articles

Association Between the Proficiency of B-Cell Receptor Signaling and the Relative Expression Levels of ZAP-70, SHIP-1, and Mir-155 in Chronic Lymphocytic Leukemia

Liguang Chen, MD, PhD, Bing Cui, PhD, Suping Zhang, PhD, George Chen, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3155.
https://doi.org/10.1182/blood.V112.11.3155.3155
Published: 2008