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Stephen V. Frye, PhD
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Journal Articles

Mertk Inhibition Promotes Anti-Leukemia Immunity By Reversing T Cell Suppression Via the PD-1 Axis

Alisa Lee-Sherick, MD, Kristen Jacobsen, PhD, Curtis J. Henry, PhD, Rebecca Parker, Xiaodong Wang, PhD, Stephen V Frye, PhD, H. Shelton Earp, MD, Deborah DeRyckere, PhD, Douglas K Graham, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4019.
https://doi.org/10.1182/blood-2018-99-119818
Published: 2018
Journal Articles

Bone Marrow Stromal Cell Mediated Resistance to Mertk Inhibition in Acute Myeloid Leukemia

Katherine A Minson, MD, Madeline G Huey, BA, Annie Qiu, Xiaodong Wang, PhD, Stephen V Frye, PhD, H. Shelton Earp, MD, Deborah DeRyckere, PhD, Douglas K Graham, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3823.
https://doi.org/10.1182/blood.V130.Suppl_1.3823.3823
Published: 2017
Journal Articles

Mertk Is a Therapeutic Target in Early T-Precursor Acute Lymphoblastic Leukemia

Ryan J Summers, MD, Katherine A Minson, MD, Stephen V Frye, PhD, Xiaodong Wang, PhD, H. Shelton Earp, III, MD, Deborah DeRyckere, PhD, Douglas K. Graham, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2536.
https://doi.org/10.1182/blood.V130.Suppl_1.2536.2536
Published: 2017
Journal Articles

MRX2843, a Novel Dual MerTK-FLT3 Inhibitor with Activity Against Resistance-Conferring FLT3 Mutations in Acute Myeloid Leukemia

Katherine A Minson, MD, Catherine C Smith, MD, Alisa B. Lee-Sherick, MD, Deborah DeRyckere, PhD, Elisabeth Lasater, PhD, Amanda A. Hill, Xiaodong Wang, PhD, Stephen V. Frye, PhD, H. Shelton Earp, MD, Neil P. Shah, MD PhD, Douglas K. Graham, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3757.
https://doi.org/10.1182/blood.V124.21.3757.3757
Published: 2014
Journal Articles

UNC2025, a Small Molecule MerTK and Flt3 Tyrosine Kinase Inhibitor, Decreases Disease Burden, Prolongs Survival, and Promotes Sensitivity to Chemotherapy in Xenograft Models of Acute Leukemia

Deborah DeRyckere, PhD, Alisa B. Lee-Sherick, MD, Amanda A. Hill, Lauren Page, BS, Xiaodong Wang, PhD, Stephen V. Frye, PhD, H. Shelton Earp, MD, Douglas K. Graham, MD PhD
Journal: Blood
Blood (2014) 124 (21): 998.
https://doi.org/10.1182/blood.V124.21.998.998
Published: 2014