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Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD

Blood (2017) 130 (Supplement 1): 38.

https://doi.org/10.1182/blood.V130.Suppl_1.38.38

Published: 2017

Journal Articles

Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy

Blood (2015) 126 (23): 817.

https://doi.org/10.1182/blood.V126.23.817.817

Published: 2015

Journal Articles

Resolving the Biological Heterogeneity of B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between DLBCL and BL (BCL-U) Using Quantitative Profiles of Oncogenic Signaling Networks

Christopher Daniel Carey, MD,, Daniel Gusenleitner, MS, Zhang Xuan, BA, Aliyah R Sohani, MD, Olga Weinberg, MD, Hongbo Yu, MD, Ben Chen, MD PhD, Bruce Woda, MD, Kai Fu, MD PhD, Stefano Monti, PhD, Scott J. Rodig, MD, PhD

Blood (2015) 126 (23): 3903.

https://doi.org/10.1182/blood.V126.23.3903.3903

Published: 2015

Journal Articles

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Blood (2015) 126 (23): 3922.

https://doi.org/10.1182/blood.V126.23.3922.3922

Published: 2015

Journal Articles

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Blood (2014) 124 (21): 74.

https://doi.org/10.1182/blood.V124.21.74.74

Published: 2014

Journal Articles

Preclinical Analyses Of The Chemical JAK2 Inhibitor, SAR302503, In Classical Hodgkin Lymphoma and Primary Mediastinal Large B-Cell Lymphoma

Yansheng Hao, MD, PhD, Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Heather Sun, Scott J. Rodig, MD, PhD, Margaret A Shipp, MD

Blood (2013) 122 (21): 4230.

https://doi.org/10.1182/blood.V122.21.4230.4230

Published: 2013

Journal Articles

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, McKeown Michael, Charles Y. Lin, PhD, Stefano Monti, PhD, Margaretha GM Roemer, Jun Qi, Peter B. Rahl, PhD, Heather Sun, Kelly T. Yeda, Andrew L. Kung, MD, PhD, Scott J. Rodig, MD, PhD, Richard A. Young, PhD, Margaret A. Shipp, MD, James E. Bradner, MD

Blood (2013) 122 (21): 3021.

https://doi.org/10.1182/blood.V122.21.3021.3021

Published: 2013

Journal Articles

CXCR4 Upregulation Is a Biomarker Of Sensitivity To Targeted Inhibition Of B-Cell Receptor Signaling In Diffuse Large B-Cell Lymphoma

Linfeng Chen, PhD, Yansheng Hao, MD, PhD, Jing Ouyang, PhD, Bjoern Chapuy, MD, PhD, Donna S. Neuberg, ScD, Thomas M Habermann, MD, Przemyslaw Juszczynski, MD, PhD, Scott J Rodig, MD, PhD, Stefano Monti, PhD, Margaret A Shipp, MD

Blood (2013) 122 (21): 631.

https://doi.org/10.1182/blood.V122.21.631.631

Published: 2013

Journal Articles

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Kunihiko Takeyama, MD, PhD, Scott J Rodig, MD, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Haig Inguilizian, MD, Craig Mermel, Treeve Currie, Ahmet Dogan, MD, PhD, Jeffery Kutok, MD, PhD, Rameen Beroukhim, MD, PhD, Donna S. Neuberg, ScD, Thomas M Habermann, MD, Gad Getz, PhD, Andrew L. Kung, MD, PhD, Todd R. Golub, MD, Margaret A. Shipp, MD

Blood (2012) 120 (21): 1534.

https://doi.org/10.1182/blood.V120.21.1534.1534

Published: 2012

Journal Articles

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Bjoern Chapuy, MD, PhD, Michael R Green, PhD, Jun Lu, PhD, Stefano Monti, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Scott J Rodig, Treeve Currie, Kunihiko Takeyama, MD, PhD, Todd R Golub, MD, PhD, Jeffery Kutok, MD, PhD, Margaret A. Shipp, MD

Blood (2010) 116 (21): 746.

https://doi.org/10.1182/blood.V116.21.746.746

Published: 2010

Journal Articles

Integrative Analysis Reveals Multiple Alterations of p53 Signaling Pathway Components In Primary Diffuse Large B-Cell Lymphomas

Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Kunihiko Takeyama, MD, PhD, Gad Getz, Scott J Rodig, Jeffery Kutok, MD, PhD, Todd R Golub, Margaret A. Shipp, MD

Blood (2010) 116 (21): 635.

https://doi.org/10.1182/blood.V116.21.635.635

Published: 2010

Journal Articles

Expression and Targeted Inhibition of the Immunoregulatory Carbohydrate-Binding Lectin, Galectin 1, in EBV-Driven Post-Transplant Lymphoproliferative Disorders.

Jing Ouyang, PhD, Przemyslaw Juszczynski, MD, PhD, Evan O'Donnell, Myriam Armant, PhD, Scott J. Rodig, MD, PhD, Kunihiko Takeyama, MD, PhD, Stefano Monti, PhD, Gabriel Rabinovich, PhD, Jeffery Lorne Kutok, MD, PhD, Jerome Ritz, MD, Margaret A. Shipp, MD

Blood (2009) 114 (22): 96.

https://doi.org/10.1182/blood.V114.22.96.96

Published: 2009

Journal Articles

Hodgkin’s Lymphoma Reed Sternberg Cells over Express the T-Cell Inhibitory Carbohydrate-Binding Lectin, Galectin 1: Role of AP-1 and Likely Mechanism of Tumor Immune Escape.

Przemyslaw Juszczynski, MD, PhD, Jing Ouyang, PhD, Jeffery L. Kutok, MD, PhD, Stefano Monti, PhD, Wen Chen, MD, Paola Dal Cin, PhD, Jeremy S. Abramson, MD, Kunihiko Takeyama, MD, PhD, Todd R. Golub, MD, Jon C. Aster, MD, PhD, Gabriel A. Rabinovich, PhD, Margaret A. Shipp, MD

Blood (2006) 108 (11): 469.

https://doi.org/10.1182/blood.V108.11.469.469

Published: 2006

Journal Articles

Inactivation of the PRDM1/BLIMP1 Gene in Non-GC-Type Diffuse Large B-Cell Lymphoma.

Laura Pasqualucci, MD, Mara Compagno, PhD, Jane Houldsworth, PhD, Stefano Monti, PhD, Adina Grunn, Margaret A. Shipp, MD, Riccardo Dalla-Favera, MD

Blood (2005) 106 (11): 2614.

https://doi.org/10.1182/blood.V106.11.2614.2614

Published: 2005

Journal Articles

Signatures of Response to the Proteasome Inhibitor Bortezomib in Diffuse Large B-Cell Lymphoma.

Friedrich Feuerhake, MD, Stefano Monti, PhD, Jonathan Blank, PhD, Erxi Wu, MD, Wen Chen, MD, Todd R. Golub, MD, PhD, Margaret A. Shipp, MD

Blood (2005) 106 (11): 608.

https://doi.org/10.1182/blood.V106.11.608.608

Published: 2005

Journal Articles

FAS Death Domain Deletions and Increased c-FLIPlong Expression Occur in Different Subtypes of Diffuse Large B-Cell Lymphoma.

Hidenobu Takahashi, MD, PhD, Friedrich Feuerhake, MD, Jeffery L. Kutok, MD, PhD, Stefano Monti, PhD, Paola S. Dal Cin, PhD, Donna Neuberg, Sc.D, Jon C. Aster, MD, PhD, Margaret A. Shipp, MD

Blood (2005) 106 (11): 416.

https://doi.org/10.1182/blood.V106.11.416.416

Published: 2005

Journal Articles

Molecular Profiling of Diffuse Large B-Cell Lymphoma Identifies Robust Subtypes Including One Characterized by Host Inflammatory Response.

Blood (2004) 104 (11): 25.

https://doi.org/10.1182/blood.V104.11.25.25

Published: 2004

Journal Articles

NFκB Activation in Primary Mediastinal Large B-Cell Lymphoma: Nuclear Localization of c-REL and Coordinate Upregulation of NFκB Target Genes.

Friedrich Feuerhake, MD, Jeffery L. Kutok, MD, PhD, Stefano Monti, PhD, Giorgio Cattoretti, MD, Paul Kurtin, MD, Geraldine S. Pinkus, MD, Laurence de Leval, MD, Nancy L. Harris, MD, Kerry J. Savage, MD, Thomas M. Habermann, MD, Riccardo Dalla-Favera, MD, Todd R. Golub, MD, Jon C. Aster, MD, PhD, Margaret A. Shipp, MD, PhD

Blood (2004) 104 (11): 243.

https://doi.org/10.1182/blood.V104.11.243.243

Published: 2004

NARROW

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy

Resolving the Biological Heterogeneity of B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between DLBCL and BL (BCL-U) Using Quantitative Profiles of Oncogenic Signaling Networks

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Preclinical Analyses Of The Chemical JAK2 Inhibitor, SAR302503, In Classical Hodgkin Lymphoma and Primary Mediastinal Large B-Cell Lymphoma

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

CXCR4 Upregulation Is a Biomarker Of Sensitivity To Targeted Inhibition Of B-Cell Receptor Signaling In Diffuse Large B-Cell Lymphoma

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Integrative Analysis Reveals Multiple Alterations of p53 Signaling Pathway Components In Primary Diffuse Large B-Cell Lymphomas

Expression and Targeted Inhibition of the Immunoregulatory Carbohydrate-Binding Lectin, Galectin 1, in EBV-Driven Post-Transplant Lymphoproliferative Disorders.

Hodgkin’s Lymphoma Reed Sternberg Cells over Express the T-Cell Inhibitory Carbohydrate-Binding Lectin, Galectin 1: Role of AP-1 and Likely Mechanism of Tumor Immune Escape.

Inactivation of the PRDM1/BLIMP1 Gene in Non-GC-Type Diffuse Large B-Cell Lymphoma.

Signatures of Response to the Proteasome Inhibitor Bortezomib in Diffuse Large B-Cell Lymphoma.

FAS Death Domain Deletions and Increased c-FLIPlong Expression Occur in Different Subtypes of Diffuse Large B-Cell Lymphoma.

Molecular Profiling of Diffuse Large B-Cell Lymphoma Identifies Robust Subtypes Including One Characterized by Host Inflammatory Response.

NFκB Activation in Primary Mediastinal Large B-Cell Lymphoma: Nuclear Localization of c-REL and Coordinate Upregulation of NFκB Target Genes.

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American Society of Hematology

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American Society of Hematology

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