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    Sirano Dhe-Paganon, PhD
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    Journal Articles

    Structure-Guided Design of DOT1L Methyltransferase Inhibitors By a Novel, Label Free Assay Platform

    Free
    Joanna S. Yi, MD, Alex Federation, Jun Qi, PhD, Sirano Dhe-Paganon, PhD, Michael Hadler, MSc, Xiang Xu, PhD, Anthony Varca, Roodolph St. Pierre, Scott A. Armstrong, MD PhD, James E. Bradner
    Journal: Blood
    Blood (2014) 124 (21): 4811.
    https://doi.org/10.1182/blood.V124.21.4811.4811
    Published: 2014
    Journal Articles

    Mutations In UBA3 Confer Resistance To The NEDD8-Activating Enzyme Inhibitor MLN4924 In Human Leukemic Cells

    Free
    G. Wei Xu, MD, PhD, Julia I. Toth, PhD, Sara R. da Silva, BSc, Stacey-Lynn Paiva, BSc, Julie L. Lukkarila, PhD, Rose Hurren, Neil Maclean, BSc, Mahadeo A. Sukhai, PhD, Rabindra N. Bhattacharjee, PhD, Carolyn A. Goard, PhD, Bruno C Medeiros, MD, Patrick T. Gunning, PhD, Sirano Dhe-Paganon, PhD, Matthew D. Petroski, PhD, Aaron Schimmer, PhD, MD
    Journal: Blood
    Blood (2013) 122 (21): 2527.
    https://doi.org/10.1182/blood.V122.21.2527.2527
    Published: 2013

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