Page 1 | Search Results | Blood | American Society of Hematology

1-13 of 13

Sort by

Sort Order Select

Journal Articles

Oncogenesis of CRLF2 Overexpression and Effect of JAK2 Inhibitor in CRLF2 Overexpressed B-Cell Acute Lymphoblastic Leukemia

Yan Gu, MD, Chunhua Song, MD, Sinisa Dovat, MD PhD, Qinglong Guo, PhD, Qinyu Ge, PhD, Zheng Ge, MD PhD

Blood (2019) 134 (Supplement_1): 2757.

https://doi.org/10.1182/blood-2019-125259

Published: 2019

Journal Articles

CK2 Inhibitor CX4945 Shows Strong In Vivo Synergistic Anti-Leukemia Activity with Rapamycin in B-ALL Due to Enhanced Ikaros Mediated Repression of mTOR Pathway

Chandrika Gowda, MBBS, Chunhua Song, MD, Yali Ding, PhD, Pavan kumar Dhanyamraju, PhD, Soumya Iyer, PhD, Jonathon Payne, Yevgeniya Bamme, MD, Arati Sharma, PhD, Kimberly J. Payne, PhD, Sinisa Dovat, MD PhD

Blood (2019) 134 (Supplement_1): 2634.

https://doi.org/10.1182/blood-2019-131790

Published: 2019

Journal Articles

CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape

Chandrika Gowda, MBBS, Chunhua Song, MD, Sadie Steffens, PhD, Yali Ding, PhD, Bo Zhang, Feng Yue, PhD, Soumya Iyer, PhD, Pavan kumar Dhanyamraju, PhD, Jonathon Payne, Morgann Reed, BS, Kimberly J. Payne, PhD, Sinisa Dovat, MD PhD

Blood (2019) 134 (Supplement_1): 2522.

https://doi.org/10.1182/blood-2019-131200

Published: 2019

Journal Articles

High-Dose TSLP Induces Co-Receptor Internalization and Signal Shutdown in Ph-like B-ALL with Overexpression of CRLF2

WayAnne B. Watson, Hossam Alkashgari, MD, Cornelia Stoian, PhD, Jacqueline S. Coats, Ineavely Baez, Hannah Choi, Benjamin Becerra, DrPH, Rishikesh Chavan, MD, Muhammad Omair Kamal, MD, Shadi Farzin Gohar, MD, Xianmei Meng, PhD, Sinisa Dovat, MD PhD, Kimberly J. Payne, PhD, Hoda Erjaee, DVM, PhD

Blood (2018) 132 (Supplement 1): 4024.

https://doi.org/10.1182/blood-2018-99-114336

Published: 2018

Journal Articles

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Charyguly Annageldiyev, Krishne Gowda, Dhimant Desai, Viola Devine, Daniel Brosius, Chandrika Gowda, MBBS, Sinisa Dovat, MD PhD, Shantu Amin, David F. Claxton, MD, Arati Sharma, PhD

Blood (2018) 132 (Supplement 1): 1440.

https://doi.org/10.1182/blood-2018-99-117376

Published: 2018

Journal Articles

Targeting High Dynamin2 Expression By Restoring Ikaros Function in Acute Lymphoblastic Leukemia

Zheng Ge, MD PhD, Jianyong Li, Baoan Chen, PhD Professor, Sinisa Dovat, MD PhD, Chunhua Song, PhD

Blood (2016) 128 (22): 2713.

https://doi.org/10.1182/blood.V128.22.2713.2713

Published: 2016

Journal Articles

A Patient-Derived Xenograft Model for Identifying Therapies and Defining Mechanisms of TSLP-Induced CRLF2 Signals in Ph-like B-ALL

Olivia L Francis, BS,PhD, Terry-Ann MIlford, BS, Ineavely Baez, BS, Jacqueline Coats, BS, Christopher L. Morris, MD PhD, Ross Fisher, MD, Benjamin Joseph Van Handel, BS, PhD, Ruijun Su, MD PhD, Batul T. Suterwala, MD, Shadi Farzingohar, MD, Sinisa Dovat, MD,PhD, Kimberly Payne, PhD

Blood (2015) 126 (23): 2633.

https://doi.org/10.1182/blood.V126.23.2633.2633

Published: 2015

Journal Articles

Epigenetic Regulation of Cell Cycle-Promoting Genes By Ikaros and HDAC1 in Acute Lymphoblastic Leukemia

Sunil Muthusami, MD, Chunhua Song, MD, PhD, Xiaokang Pan, Ph. D., Chandrika S. Gowda, MD, Kimberly J Payne, PhD, Sinisa Dovat, MD,PhD

Blood (2014) 124 (21): 3571.

https://doi.org/10.1182/blood.V124.21.3571.3571

Published: 2014

Journal Articles

Chromatin State Shaping the Gene Expression Profiling in the Inducible Differentiation of Promyelocytic Leukemia Cells

Chunhua Song, MD, PhD, Lisa Chung, PhD, Xiaokang Pan, Ph. D., Li Zhanjun, PhD, Yali Ding, PhD, Mansi Sachdev, MD, Sunil Muthusami, MD, Chandrika S. Gowda, MD, Zheng Ge, MD, PhD, Sadie Steffens, Bi-Hua Tan, MD, PhD, Christina Kendziorski, PhD, Michael Newton, PhD, Sinisa Dovat, MD,PhD

Blood (2014) 124 (21): 5188.

https://doi.org/10.1182/blood.V124.21.5188.5188

Published: 2014

Journal Articles

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

Shojaee Seyedmehdi, PhD, Zhengshan Chen, MD PhD, Maike Buchner, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Hilde Schjerven, PhD, Lai N Chan, PhD, Phillip Koeffler, MD, Cheryl L. Willman, MD, Stephen Hunger, MD, Sinisa Dovat, MD,PhD, Elisabeth Paietta, PhD, Wolf-Karsten Hofmann, Ari M Melnick, MD, Warren S. Alexander, Steven M. Kornblau, MD, Markus Muschen, MDPhD

Blood (2014) 124 (21): 787.

https://doi.org/10.1182/blood.V124.21.787.787

Published: 2014

Journal Articles

TSLP-Induced Alterations of Multiple Signaling Pathways in Primary CRLF2 B-ALL Xenografts

Parveen Shiraz, MD, Olivia Francis, MS, Ineavely Delgado, BS, Shannalee R Martinez, BS, Jacqueline Coats, MS, Katherine Salcedo Conception, BS, Karina Mayagoitia, Elizabeth Ginelli, Terry-Ann Milford, MS, Ross Fisher, MD, Christopher L. Morris, MD PhD, Xiao-bing Zhang, PhD, Ruijun Su, MD PhD, Sinisa Dovat, MD,PhD, Kimberly J Payne, PhD

Blood (2014) 124 (21): 3783.

https://doi.org/10.1182/blood.V124.21.3783.3783

Published: 2014

Journal Articles

Epigenetic Control Of Cell Cycle-Promoting Genes By Ikaros and Casein Kinase II In B-Cell Acute Lymphoblastic Leukemia

Sinisa Dovat, MD, PhD, Chunhua Song, M.D., Ph.D, Xiaokang Pan, Ph. D., Yali Ding, Ph. D., Chandrika S. Gowda, MD, Marie S Bulathsinghala, Mansi Sachdev, M.D., Haijun Wang, Kimberly J Payne, PhD

Blood (2013) 122 (21): 3734.

https://doi.org/10.1182/blood.V122.21.3734.3734

Published: 2013

Journal Articles

Mechanisms of Ikaros-Mediated Tumor Suppression

Rahul Nahar, Parham Ramezani-Rad, Sinisa Dovat, MD, PhD, Maike Buchner, Thomas G Graeber, PhD, Markus Muschen

Blood (2011) 118 (21): 408.

https://doi.org/10.1182/blood.V118.21.408.408

Published: 2011

NARROW

Oncogenesis of CRLF2 Overexpression and Effect of JAK2 Inhibitor in CRLF2 Overexpressed B-Cell Acute Lymphoblastic Leukemia

CK2 Inhibitor CX4945 Shows Strong In Vivo Synergistic Anti-Leukemia Activity with Rapamycin in B-ALL Due to Enhanced Ikaros Mediated Repression of mTOR Pathway

CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape

High-Dose TSLP Induces Co-Receptor Internalization and Signal Shutdown in Ph-like B-ALL with Overexpression of CRLF2

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Targeting High Dynamin2 Expression By Restoring Ikaros Function in Acute Lymphoblastic Leukemia

A Patient-Derived Xenograft Model for Identifying Therapies and Defining Mechanisms of TSLP-Induced CRLF2 Signals in Ph-like B-ALL

Epigenetic Regulation of Cell Cycle-Promoting Genes By Ikaros and HDAC1 in Acute Lymphoblastic Leukemia

Chromatin State Shaping the Gene Expression Profiling in the Inducible Differentiation of Promyelocytic Leukemia Cells

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

TSLP-Induced Alterations of Multiple Signaling Pathways in Primary CRLF2 B-ALL Xenografts

Epigenetic Control Of Cell Cycle-Promoting Genes By Ikaros and Casein Kinase II In B-Cell Acute Lymphoblastic Leukemia

Mechanisms of Ikaros-Mediated Tumor Suppression

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only