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Journal Articles

Pharmacologic overactivation of ALK activity by PTPN2/PTPN1 inhibition induces a combination of tumor-intrinsic oncogenic stress and immune responses to promote tumor eradication in ALK-positive lymphoma

Marta Rubin, Monica Maccagno, Martina Maggiore, Alice Pistone, Andrea Macioce, Roberta Tagliero, Gloria Arena, Simone Piane, Claudia Voena, Roberto Chiarle

Blood (2025) 146 (Supplement 1): 1772.

https://doi.org/10.1182/blood-2025-1772

Published: 2025

Journal Articles

Development of ALK-directed TCR-T cells with potent and specific anti-tumor activity against ALK-positive anaplastic large cell lymphoma

Simone Piane, Carmen Mecca, Nirmala Tilijia Pun, Ana Azambuja, Luca Alessandri, Phuc Bao Chi Nguyen, Elisa Bergaggio, Gabriele Saccu, Alessandro Gasparetto, Haley Ohlson, Claudia Voena, Marcos Simoes-Costa, Roberto Chiarle

Blood (2025) 146 (Supplement 1): 5909.

https://doi.org/10.1182/blood-2025-5909

Published: 2025

Journal Articles

Targeting CD24 “Don't Eat Me” Signal Restores Phagocytic Activity of Nurse-like Cells from Patients with Chronic Lymphocytic Leukemia

Andrea Aroldi, Mario Mauri, Daniele Ramazzotti, Simone Piane, Matteo Villa, Federica Malighetti, Chiara Borella, Elisa Bossi, Federica Cocito, Carolina Steidl, Luca Mologni, Rocco Piazza, Carlo Gambacorti-Passerini

Blood (2023) 142 (Supplement 1): 4197.

https://doi.org/10.1182/blood-2023-190359

Published: 2023