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Simón Méndez-Ferrer, PhD
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Journal Articles

Effects of Tamoxifen on the Mutant Allele Burden and Disease Course in Patients with Myeloproliferative Neoplasms - Results of the Tamarin Study

Claire Harrison, DM, FRCP, FRCPath, Joanna Baxter, PhD, Rebecca H. Boucher, BSc, MSc, PhD, Thomas McKerrell, MD PhD, Aimee Jackson, BSc, MSc, Rachel S Fletcher, PhD, Adam J. Mead, MD PhD, Steve Knapper, BMBCh, MRCP, FRCPath, DM, Joanne Ewing, MD PhD, Nauman M Butt, MD, Manish Jain, MBBS, MRCP, FRCpath, Sebastian Francis, MBChB, FRCPath, MD, Fiona J Clark, FRCP, FRCPath, Jason Coppell, MBBS, Mary Frances McMullin, MDFRCP, FRCPath, Frances Wadelin, MB ChB, PhD FRCPath, Srinivasan Narayanan, FRCP, FRCPath, Dragana Milojkovic, Mark W. Drummond, PhD FRCPath, Mallika Sekhar, MBBS, MD, Maike Paramor, James Roberts, BSc, Rachel Glover, BSc, Erica Harris, MSc, Luigi Grassi, PhD, Alba Rodriguez-Meira, PhD, Jason Carroll, PhD FMedSci, José-Ezequiel Martín, PhD, Giuditta Corbizi Fattori, PhD, Zijian Fang, BSc, Anna L Godfrey, BMBCh, PhD, Simón Méndez-Ferrer, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–35.
https://doi.org/10.1182/blood-2020-134764
Published: 2020
Journal Articles

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Ya-Hsuan Ho, Raquel del Toro, PhD, José Rivera-Torres, PhD, Justyna Rak, PhD, Claudia Korn, PhD, Andrés García-García, PhD, Lucia Kubovcakova, PhD, David Macías, PhD, Lorena Arranz, PhD, Cristina González-Gómez, Monika Wittner, PhD, Ronny Nienhold, PhD, Amie K Waller, Holly R Foster, Carlos Lopez-Otin, Randall S Johnson, PhD, Claus Nerlov, PhD, William Vainchenker, MD PhD, Cedric Ghevaert, MD PhD, Fawzia Louache, PhD, Radek C. Skoda, MD, Vicente Andrés, PhD, Simon Mendez-Ferrer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3842.
https://doi.org/10.1182/blood-2018-99-116015
Published: 2018
Journal Articles

Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

Claudia Korn, PhD, Justyna Rak, PhD, Andrés García-García, PhD, Claire Fielding, Reema Khorshed, PhD, Sara González-Antón, Juan Li, PhD, Ruggiero Norfo, PhD, E Joanna Baxter, PhD, Thomas McKerrell, MD PhD, Thomas Roberts, Hesham Eldaly, MD, Anna L Godfrey, PhD, Aracely Castillo-Venzor, Anjali Kusumbe, PhD, Adam J. Mead, MD PhD, Anthony R Green, David Kent, PhD, Cristina Lo Celso, PhD, Simon Mendez-Ferrer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 98.
https://doi.org/10.1182/blood-2018-99-113495
Published: 2018
Journal Articles

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

Valentina Salvestrini, PhD, Valentina Pensato, Marilena Ciciarello, PhD, Giorgia Simonetti, PhD, Dorian Forte, Simon Mendez-Ferrer, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 2560.
https://doi.org/10.1182/blood-2018-99-111806
Published: 2018
Journal Articles

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

Beatrice Drexler, MD, Jakob Passweg, MD, Martin Bigler, Alexandre PA Theocharides, MD, Nathan Cantoni, MD, Peter Keller, MD, Georg Stuessi, MD, Axel Rüfer, MD, Rudolf A. Benz, MD, Geneviève Favre, MD, Alexandar Tzankov, MD, Pontus Lundberg, PhD, Andrea Fuhrer, PhD, Christine Biaggi, Markus G Manz, MD, Mario Bargetzi, MD, Simon Mendez-Ferrer, PhD, Radek C. Skoda, MD
Journal: Blood
Blood (2016) 128 (22): 3108.
https://doi.org/10.1182/blood.V128.22.3108.3108
Published: 2016
Journal Articles

Noncellular Niche Influences: Nervous System Mediators, Metabolic Mediators, and Hypoxia/Oxidative Stress

Simón Méndez-Ferrer, PhD
Journal: Blood
Blood (2015) 126 (23): SCI-26.
https://doi.org/10.1182/blood.V126.23.SCI-26.SCI-26
Published: 2015
Journal Articles

Spatiotemporal Regulation of Hematopoietic Stem Cell Niches By Dual Cholinergic Signaling

Andres Garcia-Garcia, BSc, Simon Mendez-Ferrer, PhD
Journal: Blood
Blood (2015) 126 (23): 662.
https://doi.org/10.1182/blood.V126.23.662.662
Published: 2015
Journal Articles

Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Shiri Gur Cohen, PhD, Joel A. Spencer, PhD, Amir Schajnovitz, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Yookyung Jung, PhD, Guy Ledergor, MD, Idan Milo, PhD, Michael Gustave Poulos, PhD, Maria Garcia Fernandez, PhD, Alexander Kalinkovich, MDPhD, Aya Ludin, Orit Kollet, PhD, Guy Shakhar, PhD, Simon Mendez-Ferrer, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Ralf H. Adams, PhD, David T. Scadden, MD, Charles P. Lin, Tsvee Lapidot, PhD
Journal: Blood
Blood (2015) 126 (23): 664.
https://doi.org/10.1182/blood.V126.23.664.664
Published: 2015
Journal Articles

Are MSCs Stem Cells? Demonstration of in Vitro and in Vivo Stem Cell Properties of Highly Enriched lin neg /CD45 neg /CD271 pos /CD140a low/Neg Mesenchymal Stromal Cells from Adult Human Bone Marrow

Roshanak Ghazanfari, MS, Hongzhe Li, PhD, Dimitra Zacharaki, MS, Simón Méndez-Ferrer, PhD, Stefan Scheding, MD
Journal: Blood
Blood (2014) 124 (21): 4374.
https://doi.org/10.1182/blood.V124.21.4374.4374
Published: 2014
Journal Articles

Granulocyte Colony-Stimulating Factor (G-CSF) Stimulates Sympathetic Nervous System Activity in the Bone Marrow

Michela Battista, PhD, Simon Mendez-Ferrer, PhD, Paul S. Frenette, M.D.
Journal: Blood
Blood (2008) 112 (11): 2419.
https://doi.org/10.1182/blood.V112.11.2419.2419
Published: 2008
Journal Articles

Circadian Traffic of Hematopoietic Stem Cells Is Orchestrated by the Molecular Clock and Mediated by β 3 Adrenergic Signals from the Sympathetic Nervous System.

Simon Mendez-Ferrer, PhD, Daniel Lucas, PhD, Michela Battista, PhD, Jungeun Jang, MS, Paul Frenette, MD
Journal: Blood
Blood (2007) 110 (11): 219.
https://doi.org/10.1182/blood.V110.11.219.219
Published: 2007