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Shubhranshu Debnath
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Journal Articles

Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171

Agatheeswaran Subramaniam, Kristijonas Žemaitis, Mehrnaz Safaee Talkhoncheh, David Yudovich, Alexandra Bäckström, Shubhranshu Debnath, Jun Chen, Mayur Vilas Jain, Roman Galeev, Massimiliano Gaetani, Roman A. Zubarev, Jonas Larsson
Journal: Blood
Blood (2020) 136 (19): 2151–2161.
https://doi.org/10.1182/blood.2020005827
Published: 2020
Includes: Supplemental data
Journal Articles

Small Molecule Screens Identify CDK8-Inhibitors As Candidate Diamond-Blackfan Anemia Drugs

Jun Chen, MD PhD, Kavitha Siva, PhD, Tomasz Rzymski, PhD, Lars Johansson, Thomas Lundbäck, Lorena Nunez Villacis, Fredrik Ek, PhD, Bingrui Wang, Amee J George, PhD, Yang Wan, Lihong Shi, Melissa IIsley, Agatheeswaran Subramaniam, PhD, Mayur Jain, PhD, Shubhranshu Debnath, PhD, Abdul Ghani Alattar, Hanna Axelsson, Milena Mazan, PhD, Eliza Majewska, Ulf R. Tedgard, MD PhD, Marcin W. Wlodarski, MD PhD, Anna-Lena Gustavsson, Roger Olsson, Michal Mikula, Xiaofan Zhu, PhD, Krzysztof Brzózka, PhD, Ross Hannan, PhD, Johan Flygare, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 753.
https://doi.org/10.1182/blood-2018-99-114570
Published: 2018
Journal Articles

Inhibition of Lysine-Specific Demethylase 1A (LSD1) Supports Human HSCs in Culture By Preserving Their Immature State

Agatheeswaran Subramaniam, PhD, Mehrnaz Safaee Talkhoncheh, Kristijonas Zemaitis, Shubhranshu Debnath, PhD, Jun Chen, MD PhD, Mayur Jain, PhD, Roman Galeev, MD, Jonas Larsson, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 194.
https://doi.org/10.1182/blood-2018-194
Published: 2018
Journal Articles

Gene Therapy Corrects the Lethal Bone Marrow Failure in a Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia

Pekka Jaako, Shubhranshu Debnath, Karin Olsson, Axel Schambach, MD, PhD, Christopher Baum, MD, Johan Flygare, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 513.
https://doi.org/10.1182/blood.V120.21.513.513
Published: 2012
Journal Articles

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

Brief Report
Pekka Jaako, Shubhranshu Debnath, Karin Olsson, David Bryder, Johan Flygare, Stefan Karlsson
Journal: Blood
Blood (2012) 120 (11): 2225–2228.
https://doi.org/10.1182/blood-2012-05-431437
Published: 2012
Includes: Supplemental data
Journal Articles

Bone Marrow Failure in RPS19-Deficient Mice Is Partly Caused by p53 Activation and Responds to L-Leucine Treatment

Pekka Jaako, Shubhranshu Debnath, Karin Olsson, Johan Flygare, Stefan Karlsson, M.D., Ph.D., Prof.
Journal: Blood
Blood (2011) 118 (21): 727.
https://doi.org/10.1182/blood.V118.21.727.727
Published: 2011